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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

Displaying 1 - 10 of 4542 results
  1. High throughput Electrophysiological Purification Array HEPA for cell based therapies

    SBC: BIOPICO SYSTEMS Inc.            Topic: NHLBI

    DESCRIPTION provided by applicant High throughput Electrophysiological Purification Array HEPA for cell based therapies Abstract Patient specific reprogrammed somatic cells induced pluripotent stem cells or iPSCs have raised hope for revolutionary regenerative treatments for heart lung and blood diseases and drug development applications For example these iPS cells can be differentiated ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  2. Plasmodium Falciparum Whole Sporozoite Malaria Vaccine

    SBC: SANARIA INC.            Topic: NIAID

    DESCRIPTION provided by applicant The ideal tool for eliminating Plasmodium falciparum Pf the causative agent of of all malaria deaths would be a highly effective vaccine that prevents blood stage infection and thereby prevents the disease and transmission The only immunogens demonstrated in humans to be able to induce andgt protective efficacy that is sustained months are ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  3. Development of the VirtualTAVR system for diagnostics and preventative strategies

    SBC: Dura LLC            Topic: NHLBI

    DESCRIPTION provided by applicant Since the first procedure in there has been an explosive growth in transcatheter aortic valve replacement TAVR Up to date more than TAVR had been performed worldwide Despite the increased global experience with TAVR severe adverse events associated with TAVR have been extensively documented including annulus rupture coronary occlusion para ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Nutritional Intervention for Age Related Muscular Function and Strength Losses

    SBC: MTI Biotech Incorporated            Topic: NIA

    DESCRIPTION provided by applicant Sarcopenia defined as age related loss of muscle mass and muscle function and strength is very prevalent among the elderly Sarcopenia is one of the largest public health problems facing a rapidly increasing aging population in the United States and leads to increased incidence of falls fractures and associated morbidities Previous observations from our la ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Randomized Prospective Phase II Clinical Trial of NVX in Association with Chemoradiation of Glioblastoma

    SBC: NUVOX PHARMA, L.L.C.            Topic: 102

    Glioblastoma multiforme GBM is a malignant primary brain tumor affecting about new cases per year in the U S Average survival is only about months Radiation RT is most commonly administered as fractions of Gray each over weeks with concomitant temozolomide TMZ GBM tumors are hypoxic The primary mechanism of RT is creation of singlet oxygen hypoxia within GBM adversel ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Selection-driven plant metabolites for treatment of CNS diseases

    SBC: NAPROGENIX, INC.            Topic: 150

    DESCRIPTION provided by applicant This project aims to demonstrate that the evolution of plant biosynthetic pathways can be accelerated and driven to favor the synthesis of ligands which interact with a specific human target protein This is achieved by subjecting mutant plant cells to selection pressures favoring the survival of mutants with the phenotype of interest As an example this appro ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  7. Promoting Responsible Drinking: An Internet-based, Interactive Computer Tailored Intervention

    SBC: Pro-Change Behavior Systems Inc            Topic: NIAAA

    DESCRIPTION provided by applicant Excessive alcohol use is associated with a range of serious and costly health social and economic consequences at the individual and societal level This program of research serves as a venue by which to produce and test an innovative science based and cost effective means to intervene in a private convenient and individualized way with employed adults wh ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  8. IGF OT IGF A SHARED DECISION MAKING TOOL TO PREVENT SUBSTANCE ABUSE N DA PERIOD OF PERFORMANCE SEPTEMBER MARCH BASE AWARD

    SBC: RINGFUL LLC            Topic: NIDA

    Not Available

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  9. IGF OT IGF EVORX TECHNOLOGIES INC

    SBC: EVORX TECHNOLOGIES, INC.            Topic: NCI

    Not Available

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. IGF OT IGF SBIR TOPIC

    SBC: MODULATION THERAPEUTICS, INC.            Topic: NCI

    Not Available

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health

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