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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Molecular Evolution of Chondroitinase ABCI for SCI

    SBC: Acorda Therapeutics, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Spinal cord injury (SCI) is a devastating event affecting approximately 11,000 individuals each year in the US alone. Although most victims survive, the individual is often paralyzed for the rest of his or her life. Sixty percent of injuries occur in individuals between the ages of 16 and 30. Life-time medical costs average about $1.5 million dollars per patie ...

    SBIR Phase I 2005 Department of Health and Human Services
  2. Effects of Chondroitinase and Training in Acute SCI

    SBC: Acorda Therapeutics, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Spinal cord injury (SCI) inflicts trauma to the cells and tissues of the central nervous system and typically results in debilitating loss of function below the level of injury, for which no effective treatment exists. Chondroitin Sulfate Proteoglycans (CSPGs) an important component of the glial scar. The majority are potently inhibitory for axonal growth and ...

    SBIR Phase I 2005 Department of Health and Human Services
  3. Chimeric proteins for the treatment of spinal cord injury

    SBC: Acorda Therapeutics, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Spinal cord injury (SCI) inflicts trauma to the cells and tissues of the central nervous system and causes a severe and debilitating condition in the individual. Following SCI, limited regeneration of injured neurons results in permanent disability characterized by some loss of sensation, paralysis and autonomic dysfunction. One reason that neurons fail to rege ...

    SBIR Phase I 2005 Department of Health and Human Services
  4. Standardized Medicare/Medicaid Reimbursement for HCPP and other Small Payers

    SBC: Advanced Management Research            Topic: N/A

    N/A

    SBIR Phase II 1998 Department of Health and Human Services
  5. Electronic Image Trial Management System

    SBC: VIRTUALSCOPICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Delays in FDA drug approval are measured in lost lives (estimated to be hundreds of thousands over the last few decades) and increased costs to U.S. citizens for drugs that are eventually approved. One factor contributing to the delay in drug approvals is the widespread use of time-consuming and error-prone manual methods to deliver medical images (i.e. CT, MR, ...

    STTR Phase I 2009 Department of Health and Human Services
  6. Cardiac Regenerative Therapy with Cyclin A2

    SBC: VentriNova, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The morbidity and mortality due to cardiovascular disease is attributed to the lack of significant replicative potential of adult mammalian cardiomyocytes. Thus myocyte loss in response to ischemic injury typically results in scar formation and a decline of cardiac function that is usually irreversible. The cessation of myocyte proliferation is associated with ...

    STTR Phase I 2009 Department of Health and Human Services
  7. Hydronic, High-Speed, Focal Thermal Stimulator

    SBC: ALA SCIENTIFIC INSTRUMENTS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Cloning of hot and cold thermal receptors has advanced the understanding of the molecular basis of thermal sensation. Two (2) important remaining questions to be addressed are the identification of additional thermal receptor genes and the elucidation of the mechanism(s) that enable the receptor proteins to alter gating properties in response to changes in temp ...

    STTR Phase II 2005 Department of Health and Human Services
  8. A PATTERN RECOGNIZING EEG MONITORING DEVICE

    SBC: Alacron, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1989 Department of Health and Human Services
  9. 18 MC ANALOGS AS POTENTIAL ANTIADDICTIVE AGENTS

    SBC: ALBANY MOLECULAR RESEARCH, INC.            Topic: N/A

    N/A

    SBIR Phase I 1998 Department of Health and Human Services
  10. PIPER PROSTATE IMPLANT PLANNING ENGINE FOR RADIOTHERAPY

    SBC: Alpha Interventional, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1998 Department of Health and Human Services
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