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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Phase II SBIR: Responding to NDM-1- Advancement of a new MBL inhibitor to IND

    SBC: VenatoRx Pharmaceuticals, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Multi drug resistance in Enterobacteriaceae is regarded as a healthcare crisis While carbapenems are among the most prescribed antibiotics for infections caused by these organisms carbapenem resistance conferred by zinc based metallo carbapenemases Amber Class B is a growing global health concern that threatens to erode the efficacy of these antibiotics both in th ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  2. Preserving beta-lactam utility vs pathogens producing any class of beta-lactamase

    SBC: VenatoRx Pharmaceuticals, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Multi drug resistance in Enterobacteriaceae is regarded as a healthcare crisis This crisis has been further amplified by the recent emergence of the NDM andquot super bug geneandquot a zinc based metallo lactamase Amber Class B in Enterobacteriaceae Members of this family of resistance enzymes are found on promiscuous plasmids with other MDR resistance mechanisms ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  3. Development of a Urine Test for the Early Detection of Liver Cancer

    SBC: JBS Science, Inc            Topic: NCI

    DESCRIPTION provided by applicant Development of a urine test for the early detection of liver cancer The need to develop an effective method of detecting hepatocellular carcinoma HCC is urgent HCC is the third leading cause of cancer deaths and has a year survival rate of less than If HCC is identified early the survival rate can be as high as The survival rate drops significantly however to as l ...

    SBIR Phase II 2013 Department of Health and Human Services
  4. In-Patient Pediatric Gastrojejunal Tube Cleaner Eliminating Surgical Intervention

    SBC: ACTUATED MEDICAL, INC.            Topic: NICHD

    DESCRIPTION provided by applicant In this Phase II NIH SBIR Actuated Medical Inc will complete the development of the Pedi GJ ClearTM device for clearing occlusions and restoring patency in situ to pediatric gastrojejunal feeding tubes GJ tubes eliminating the need to surgically replace clogged tubes Public Health Problem Enteral nutrition is provided for patients that have a functioning lower gas ...

    SBIR Phase II 2013 Department of Health and Human Services
  5. Novel schemes for highly reliable aerospace electromechanical primary actuation systems

    SBC: LCDRIVES CORP.            Topic: SB132005

    There is a need to achieve 10^-9 reliability for actuators for critical aerospace applications and this precludes single point failure for all but the simplest and most reliable electrical and mechanical components. LC Drives proposes a method of constructing a high reliability linear actuator for critical aerospace applications that is designed such that jams caused by conventional electrical a ...

    SBIR Phase I 2013 Department of DefenseDefense Advanced Research Projects Agency
  6. Peridynamics Based Multiscale Modeling of Damage in Thick Composites

    SBC: Advanced Cooling Technologies, Inc.            Topic: N132101

    Fiber reinforced composites are attractive for several light-weight defense and aerospace applications. However, their inherent anisotropy and complex failure mechanisms limit their use in high-performance structures or components. In order to accurately predict the damage behavior and durability of composite parts exposed to extreme conditions, there is a need to develop new analysis tools that c ...

    SBIR Phase I 2013 Department of DefenseNavy
  7. Development of a Recombinant Vaccine Against Streptococcus Pyogenes Infection and Disease

    SBC: VAXFORM, LLC            Topic: A12aT027

    A vaccine to protect against diseases resulting from infection with Streptococcus pyogenes is under development. This vaccine utilizes a recombinant fusion protein (SpeAB) comprising of genetically detoxified SpeA, a secreted toxin, and SpeB, a surface bound and secreted cysteine protease. During phase I investigations a lead vaccine formulation was determined by optimization of critical paramet ...

    STTR Phase II 2013 Department of DefenseArmy
  8. Heat-Pipe Embedded Exhaust Heat Recovery System

    SBC: Advanced Cooling Technologies, Inc.            Topic: A12016

    This Small Business Innovation Research (SBIR) program will develop a thermoelectric generator (TEG) that will improve the overall efficiency of 100-kW class generator sets (gensets) by 5-10%. Advanced Cooling Technologies, Inc. (ACT) proposes a novel heat-pipe embedded thermoelectric generator to convert exhaust heat directly into useful electrical energy. The proposed concept improves upon curre ...

    SBIR Phase II 2013 Department of DefenseArmy
  9. Wave Detection, Prediction, and Reaction System (WDPRS)

    SBC: DANIEL H. WAGNER ASSOCIATES, INCORPORATED            Topic: N10AT036

    In this Phase II SBIR project, Daniel H. Wagner Associates (DHWA), with NASAs Jet Propulsion Laboratory (JPL), MARK Resources, Inc. (MRI), and Spatial Integrated Systems (SIS) as our subcontractors, will develop a prototype lightweight, low-cost Wave Detection, Prediction, and Reaction System (WDPRS), and then test and evaluate its performance at-sea. The proposed WDPRS is designed to reduce the h ...

    SBIR Phase II 2013 Department of DefenseNavy
  10. Adaptive Gaming and Training Environment for Maintenance Operations

    SBC: SONALYSTS, INC.            Topic: AF121017

    ABSTRACT: The ultimate goal of this Phase II SBIR is to provide the Air Force with a game-based approach to train Air Force maintenance personnel. Sonalysts believes that the most cost-effective solution will include: The continued development of specifications for a SAM-T that uniquely uses game engine AI, scenario generation, IMI, IETMs, event management, performance tracking tools, and eve ...

    SBIR Phase II 2013 Department of DefenseAir Force

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