Award Data

IN THE TREATMENT OF THE DYNAMIC PROBLEMS OF STRUCTURES, TWO ALTERNATE TESTING METHODS, BASED ON EXTERNAL AND EMBEDDED SENSORS, EXIST IN THE LITERATURE. IF THE SENSORS RESPOND TO THE CHANGES IN THE DYNAMIC CHARACTERISTICS OF THE STRUCTURE, AND/OR THE ENVIRONMENT, THEN THEY ARE REFERRED TO "SMART" STRUCTURES. SMART SENSORS AND SMART MATERIALS HAVE BEEN USED FOR DETECTING STRUCTURAL DAMAGES AND/OR CO ...

DESCRIPTION (provided by applicant): Calista Therapeutics has invented Calcaftor, a first-in-class peptide drug that can treat all Cystic Fibrosis (CF) patients. Calcaftor is validated in the gold standard pre-clinical model of CF using F508 -CFTR lung tissue harvested from CF transplant patients. Results from this model demonstrated a gt25 hour duration of action that enables once daily inhaled n ...

A novel method for preparing carbon electrode structures having applications in electrochemical double layer capacitors (EDLCs) is described. The method for preparing these structures employs carbon (graphite) nano fiber materials and results in an electrode having both high surface area and high electronic conductivity; two essential characteristics for EDLC electrodes. The fabrication process ...

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The overarching objective of this project is to develop an innovative technological tool that will facilitate the implementation of an evidence-based substance abuse prevention program and related health behavior risk programs among military personnel. PUBLIC HEALTH RELEVANCE

DESCRIPTION (provided by applicant): A Phase I SBIR program of preclinical development is proposed focusing on the development of an active specific immunotherapeutic called Cellarium for treatment of glial cell-based cancers. Successful completion of this project will establish the minimum level of therapeutic feasibility and lead to further development of the vaccine in preparation for f ...

This program proposes to demonstrate an ultra-low power design methodology and circuits for digital logic employing advanced dynamic voltage scaling (DVS) for asynchronous NULL Convention Logic (NCL) circuits operating in sub-threshold to super-threshold voltage regimes. The power supply voltages of logic block partitions will be independently set by on-chip voltage controllers based on the data p ...

DESCRIPTION (provided by applicant): Neonatal hypoxia-ischemia (HI) remains a major cause of acute perinatal brain injury, leading ultimately to neurologic dysfunction manifesting as cerebral palsy, mental retardation, and epilepsy. Cerebral oxygen deprivation and/or reduced blood flow due to umbilical cord occlusion, prolonged labor, and/or intracranial hemorrhage produce an inflammatory respons ...

This project is based on a novel computer graphics technology for man/machine interfaces that relies on machine learning techniques, neural-like networks, and object recognition IU techniques. The key idea is to use a few "example" views of an object or person, to teach the computer to generate other views, under user control. WIth our technology we will develop an interactive (multimedia) interfa ...

Investment castings have well served both the military and commercial markets in such areas as waveguides and splitters for microwave applications, and for connectors, housings, heat sinks and mechanical parts for electronics, optical, instrumentation, and medical devices. Tomorrow's higher RF millimeter wave and communications electronics products, and more compact optical, instrumentation and m ...