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Award Data
The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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AAV2-ASPA-Based Metabolic Intervention for Alzheimer's Disease
SBC: ASKLEPIOS BIOPHARMACEUTICAL, INC. Topic: NIAAbstract We propose to initiate preclinical development of a gene therapeutic targeted to Alzheimer's Disease. The World Health Organization's and Alzheimer's Disease International's report on Dementia (2012) recognizes that the global burden of AlzheimerDisease is forecast to worsen significantly with prevalence predicted to double every 20 years. Interventions that could prov ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
A biomarker of aging as a predictor of kidney transplant function
SBC: HEALTHSPAN DIAGNOSTICS, LLC Topic: NIAABSTRACT The number of kidney transplant candidates on the waiting list continues to increase each year, while the number of kidney donations remains stagnant. The enduring donor shortage compels clinicians to use kidneys from marginal donors, referred toas expanded criteria donors (ECD). ECD kidneys, obtained primarily from older donors, have a higher risk of delayed graft function and graft loss ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Affinity Capture Peptides for Clinical Mass Spectrometric Assays in Plasma
SBC: AFFINERGY, LLC Topic: NIGMSDESCRIPTION (provided by applicant): We will develop the first assay for multiplexed combinations of all 14 Bone Morphogenetic Proteins. Immunoassays are the gold standard for measuring proteins in clinical samples. However these antibody- based tests neither quantitate protein analyte variants, nor multiplex across large numbers of superfamily members. In addition, the availability of polyclona ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Alternative human cell-based models of fatty liver disease
SBC: Zen-Bio, Inc. Topic: NIDDKDESCRIPTION (provided by applicant): Obesity and Type 2 diabetes affect the lives of millions of people worldwide, add significantly to health-related expenditures, and are seemingly unmanageable health issues, since rates of occurrence are steadily increasing. In parallel with the increasing incidence of obesity and insulin resistance, is the occurrence of non-alcoholic fatty liver disease (NAFLD ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
A MicroRNA Approach to Screen for Sporadic Colon Cancer Exfoliately in Human Stoo
SBC: GEM TOX CONSULTANTS AND LABS, INC. Topic: NCIDESCRIPTION (provided by applicant): The aim of this submission is to develop a quantitative microRNA assay for screening right and left colon cancer in stool of patients, particularly at the early adenoma stage (e.g., polyps 3 1 cm with high grade dysplasia), which shows higher sensitivity than FOBT, and results in better compliance and is more economical than invasive colonoscopy. We studied ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
A New Dual-Gated MCT (DMCT) for Hybrid Electric Power Systems
SBC: POWER TECHNOLOGY SERVICES (PTS), INC. Topic: N/AN/A
SBIR Phase I 1996 Department of DefenseDefense Advanced Research Projects Agency -
A Novel Approach to the Treatment of Cardiac Arrhythmia: A Robotic Catheter for E
SBC: LifeSciTech, LLC Topic: NHLBIDESCRIPTION (provided by applicant): The primary objective of this Phase II research is to design, fabricate, and surgically evaluate a robotic catheter for endocardial ablation procedures. Phase I research successfully demonstrated the feasibility of this concept through the development of a tele-operated catheter prototype with shape memory alloy (SMA) actuated bending segments. Phase II researc ...
SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health -
A Novel Biomimetic Bone Cement For Immediately Loaded Dental Implants
SBC: SOUTHEAST TECHINVENTURES INC Topic: NIDCRDESCRIPTION (provided by applicant): The worldwide market for implant-based dental reconstruction products will approach nearly 3.5 billion by 2010 with an annual growth rate of 15%. Currently, an implant patient waits 3-14 months from the time of tooth extraction until a functioning crown is in place, resulting in significant inconvenience for the patient and high cost for the overall procedure. ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
A Novel, Compact, Wide Field of View, Multiphoton Microscope
SBC: LASER BIOPSY, INC. Topic: NCIDESCRIPTION (provided by applicant): Laser Biopsy Inc, (LBI) has a vision of improving the speed and quality of cancer diagnosis with reduced patient risk and reduced cost. LBI is developing a new medical imaging system that will enable pathologists to perform real-time diagnosis of biopsies taken during surgical procedures. Most cancer diagnoses are made by biopsying the suspicious lesions under ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
A novel therapeutic approach for Acute Lung Injury/ARDS
SBC: BIOMARCK PHARMACEUTICALS, LTD Topic: NHLBIDESCRIPTION (provided by applicant): The objective of the proposed project is to advance the development of novel peptides targeting MARCKS (Myristoylated Alanine-Rich C Kinase Substrate) protein as platform drug molecules for the treatment of Acute Lung Injury (ALI) and its more severe form, Acute Respiratory Distress Syndrome (ARDS), thereby providing the first pharmacologic therapeutic for this ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health