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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. OPTIMAL ISLET MATRIX FOR IMMUNOISOLATED TRANSPLANTS

    SBC: Cytotherapeutics, Inc.            Topic: N/A

    THE LONG TERM OBJECTIVE OF THIS RESEARCH IS THE DEVELOPMENT AND INTRODUCTION INTO CLINICAL PRACTICE OF AN EFFECTIVE, AND BIOCOMPATIBLE IMPLANTABLE-HYBRID- ARTIFICIAL-PANCREAS WHICH IS CAPABLE OF SIGNIFICANT IMPROVEMENT IN THERAPY OF INSULIN DEPENDENT DIABETES. THE SPECIFIC AIM OF THIS PROJECT IS TO INVESTIGATE METHODS OF IMPROVING THE VIABILITY AND FUNCTION OF MACRO-ENCAPSULATED ISLETS. DEVELOPMEN ...

    SBIR Phase I 1991 Department of Health and Human Services
  2. CPR FOR FAMILIES\VIDEOTAPE DEVELOPMENT

    SBC: Institute For Behavioral Medic            Topic: N/A

    N/A

    SBIR Phase I 1991 Department of Health and Human Services
  3. Calcaftor, a CFTR stabilizer for Cystic Fibrosis treatment

    SBC: Calista Therapeutics, Inc.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Calista Therapeutics has invented Calcaftor, a first-in-class peptide drug that can treat all Cystic Fibrosis (CF) patients. Calcaftor is validated in the gold standard pre-clinical model of CF using F508 -CFTR lung tissue harvested from CF transplant patients. Results from this model demonstrated a gt25 hour duration of action that enables once daily inhaled n ...

    SBIR Phase I 2014 Department of Health and Human Services
  4. Inter-alpha-inhibitors in Hypoxic-Ischemic Brain Injury

    SBC: PROTHERA BIOLOGICS, LLC            Topic: NINDS

    DESCRIPTION (provided by applicant): Neonatal hypoxia-ischemia (HI) remains a major cause of acute perinatal brain injury, leading ultimately to neurologic dysfunction manifesting as cerebral palsy, mental retardation, and epilepsy. Cerebral oxygen deprivation and/or reduced blood flow due to umbilical cord occlusion, prolonged labor, and/or intracranial hemorrhage produce an inflammatory respons ...

    SBIR Phase I 2014 Department of Health and Human Services
  5. IGF::OT::IGF High-Impact Substance Abuse Prevention Technologies. SBIR Phase I. Period of Performance 7/16/2014-1/15/2015

    SBC: Pro-Change Behavior Systems Inc            Topic: NIDA

    The overarching objective of this project is to develop an innovative technological tool that will facilitate the implementation of an evidence-based substance abuse prevention program and related health behavior risk programs among military personnel. PUBLIC HEALTH RELEVANCE

    SBIR Phase I 2014 Department of Health and Human Services
  6. THIS PROJECT CONCERNS A UNIQUE APPROACH TO THE PRODUCTION OFHIGH ENERGY PRODUCT MAGNETS EMPLOYING RAPID SOLIDIFICATION METHODS.

    SBC: Stam Inc.            Topic: N/A

    THIS PROJECT CONCERNS A UNIQUE APPROACH TO THE PRODUCTION OFHIGH ENERGY PRODUCT MAGNETS EMPLOYING RAPID SOLIDIFICATION METHODS. RIBBONS OF RARE EARTH-COBALT ALLOYS ARE RAPIDLY SOLIDIFIED TO PRODUCE A MICRON-SIZED COLUMNAR MICROSTRUCTUREAND THE COERCIVE FORCE DURING MAGNETIZATION IS CONTROLLED BY DOMAIN NUCLEATION MECHANISM. THIS EFFORT PRODUCES HIGH- CURIE-POINT, HIGH-ENERGY-PRODUCT PERMANENT MAGN ...

    SBIR Phase I 1983 National Aeronautics and Space Administration
  7. Integration of Complex Geometry, 3D Woven Preforms via Innovative Stitching Technique

    SBC: T.E.A.M., INC.            Topic: H701

    Thick, 3D woven carbon/phenolic composites offer potential improvement over legacy thermal protection systems (TPS) for re-entry vehicle heat shield applications. However due to the scale and complexity of typical re-entry vehicle structures, it is likely that multiple 3D woven panels would need to laid up to create the overall heat shield, creating a potential weak spots at the panel joints. ...

    SBIR Phase I 2014 National Aeronautics and Space Administration
  8. Advancing High Energy Lithium-Sulfur Batteries

    SBC: Yardney Technical Products, Inc.            Topic: Z102

    Lithium-Ion batteries have been a main source of energy for many aerospace applications over the past decade. Future space missions are facing a number of challenging requirements, including significant increase in specific energy, approaching 500 Wh/kg, and energy density of 700 Wh/l at cell level. Compared to state-of-the-art technology today, a reduction in mass and volume are necessary, along ...

    SBIR Phase I 2014 National Aeronautics and Space Administration
  9. THE RESEARCH HEREIN PROPOSED IS INTENDED TO ADDRESS THE CONTINUING PROBLEM OF ESTIMATING SOFTWARE COSTS OVER THE LIFE OF LARGE AND COMPLEX SOFTWARE PROJETS.

    SBC: Aquidneck Management Associate            Topic: N/A

    THE RESEARCH HEREIN PROPOSED IS INTENDED TO ADDRESS THE CONTINUING PROBLEM OF ESTIMATING SOFTWARE COSTS OVER THE LIFE OF LARGE AND COMPLEX SOFTWARE PROJETS. THE RESEARCH WILL ADDRESS ALL FACTORS THAT AFFECT SOFTWARE COSTS FROM A FUNCTIONAL STANDPOINT AS OPPOSED TO THE TRADITIONAL LINES-OF-CODE (PROGRAM SIZE) APPROACH. THE FACTORS WILL BE TRANSLATED INTO A MODEL THAT EMPHASIZES THE IMPORTANCE OF IN ...

    SBIR Phase I 1983 Department of DefenseAir Force
  10. CAD STATION RM ON-LINE SUPPORT SYSTEM

    SBC: Aquidneck Management Associate            Topic: N/A

    THIS PROJECT OUTLINES A RELIABILITY AND MAINTAINABILITY KNOWLEDGE BASE AND THE HYPERTEXT INTERFACE REQUIRED TO TRANSPORT THIS DATA INTO COMPUTER-AIDED DESIGN (CAD) ENVIRONMENTS. THE PRIMARY FOCUS OF THE PROPOSAL IS THE DEVELOPMENT OF THE FOUNDATION FOR AN ENGINEERING RELIABILITY AND MAINTAINABILITY INFORMATION PRESENTATION SYSTEM TO SUPPORT ELECTRONIC CIRCUIT AND SYSTEMS DESIGN ENGINEERS IN A CAD ...

    SBIR Phase I 1991 Department of DefenseAir Force

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