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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Optimum Control of Induction Generators for Water Current Energy Harnessing

    SBC: Electro Standards Laboratory, Inc.            Topic: 815

    Optimization of generator performance and maximization of output power are difficult to attain in the generation of hydro-power. This is due to the changing water conditions and corresponding changes in the form of available energy. ESL proposes to use self-tuning controls in combination with a suitably chosen and optimized generator driven by hydro-energy and condition it for distributi ...

    SBIR Phase I 2010 Department of Commerce
  2. Autonomous Power Management for Hearing Aids and Hearing Products

    SBC: PACKET DIGITAL LLC            Topic: NIDCD

    DESCRIPTION (provided by applicant): Loss of hearing affects the quality of life for individuals. The number of Americans with hearing loss is increasing as baby boomers age and younger citizens damage their hearing with personal audio devices. By 2025, approximately 40 million Americans are projected to be hearing impaired, an increase of 23% from current numbers. Hearing loss may be treated, but ...

    SBIR Phase I 2010 Department of Health and Human Services
  3. Promoting Health During Pregnancy: A Multiple Behavior Computer Tailored Interven

    SBC: Pro-Change Behavior Systems Inc            Topic: NCCDPHP

    DESCRIPTION (provided by applicant): Pregnant women, particularly those from underserved populations, often have a multitude of behavioral risks that threaten positive pregnancy and birth outcomes, as well as the future health of mother and baby. This application represents innovative research for impacting the promotion of healthy behaviors among pregnant women. The objective is to develop and te ...

    SBIR Phase II 2010 Department of Health and Human Services
  4. VLP-Based Antibody-Inducing Vaccines for HIV-1

    SBC: ALTRAVAX, INC            Topic: NIAID

    DESCRIPTION (provided by applicant): The HIV-1 epidemic has resulted in ~2.7 million new infections in 2007 for a total of ~33 million people living with HIV/AIDS. Clinical trials have shown that HIV-1 infection cannot be prevented by immunization with monomeric recombinant forms of viral envelope (Env) proteins. However, it is clear that the HIV-1 Env contains epitopes that can induce neutralizin ...

    SBIR Phase I 2010 Department of Health and Human Services
  5. Improved Vaccines for Influenza B Virus

    SBC: ALTRAVAX, INC            Topic: NIAID

    DESCRIPTION (provided by applicant): Influenza is a major cause of morbidity and mortality around the world. In the United States, seasonal epidemics of flu occur from late fall to early spring affecting all age groups but with especially high rates of infection in children. Serious illness and death are consequences of influenza infection among the elderly, young children, and individuals with o ...

    SBIR Phase I 2010 Department of Health and Human Services
  6. Designing Improved HIV-1 Envelope Proteins as Vaccine Candidates

    SBC: ALTRAVAX, INC            Topic: NIAID

    DESCRIPTION (provided by applicant): The HIV-1 epidemic has resulted in ~2.7 million new infections in 2007 for a total of ~33 million people living with HIV/AIDS. Clinical trials have shown that HIV-1 infection cannot be prevented by immunization with monomeric recombinant forms of viral envelope (Env) proteins. However, it is clear that the HIV-1 Env contains epitopes that can induce neutralizin ...

    SBIR Phase I 2010 Department of Health and Human Services
  7. Immunotherapeutic Biomaterials for Treatment of Glioma

    SBC: IN CYTU, INC.            Topic: NINDS

    DESCRIPTION (provided by applicant): A Phase I SBIR program of preclinical development is proposed focusing on the development of an active specific immunotherapeutic called Cellarium for treatment of glial cell-based cancers. Successful completion of this project will establish the minimum level of therapeutic feasibility and lead to further development of the vaccine in preparation for f ...

    SBIR Phase I 2010 Department of Health and Human Services
  8. Calcaftor, a CFTR stabilizer for Cystic Fibrosis treatment

    SBC: Calista Therapeutics, Inc.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Calista Therapeutics has invented Calcaftor, a first-in-class peptide drug that can treat all Cystic Fibrosis (CF) patients. Calcaftor is validated in the gold standard pre-clinical model of CF using F508 -CFTR lung tissue harvested from CF transplant patients. Results from this model demonstrated a gt25 hour duration of action that enables once daily inhaled n ...

    SBIR Phase I 2014 Department of Health and Human Services
  9. Inter-alpha-inhibitors in Hypoxic-Ischemic Brain Injury

    SBC: PROTHERA BIOLOGICS, LLC            Topic: NINDS

    DESCRIPTION (provided by applicant): Neonatal hypoxia-ischemia (HI) remains a major cause of acute perinatal brain injury, leading ultimately to neurologic dysfunction manifesting as cerebral palsy, mental retardation, and epilepsy. Cerebral oxygen deprivation and/or reduced blood flow due to umbilical cord occlusion, prolonged labor, and/or intracranial hemorrhage produce an inflammatory respons ...

    SBIR Phase I 2014 Department of Health and Human Services
  10. IGF::OT::IGF High-Impact Substance Abuse Prevention Technologies. SBIR Phase I. Period of Performance 7/16/2014-1/15/2015

    SBC: Pro-Change Behavior Systems Inc            Topic: NIDA

    The overarching objective of this project is to develop an innovative technological tool that will facilitate the implementation of an evidence-based substance abuse prevention program and related health behavior risk programs among military personnel. PUBLIC HEALTH RELEVANCE

    SBIR Phase I 2014 Department of Health and Human Services

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