Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Automation and validation of human on a chip systems for drug discovery

    SBC: Hesperos, Inc.            Topic: 950

    Project Summary AbstractOur overall strategy for Hesperos is to utilize microphysiological systems in combination with functional readouts to establish platforms capable of analysis of chemicals and drug candidates for toxicity and efficacy during pre clinical testingThis is a service based company that is developing low cost in vitro systems containing a novelpumplessmicrophysiological platform a ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Development of AAV vectors for long-term expression of eCD4-Ig

    SBC: EMMUNE, INC.            Topic: NIAID

    ABSTRACTSUMMARYPROJECT DESCRIPTION A single intramuscular injection of an adeno associated virusAAVvector that expresses eCDIg has the potential to treat or prevent HIVinfection for a lifetimeeCDIg is a synthetic antibody orimmunoadhesinconstructed by fusing parts of the viral receptorCDand coreceptorCCRto the constant region of an antibodyBecause eCDIg binds the HIVenvelope glycoproteinEnvthrough ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Pancreatic Ductal Adenocarcinoma Targeted Ultrasound Contrast Agent Development

    SBC: NUVOX PHARMA, L.L.C.            Topic: 102

    Pancreatic ductal adenocarcinomaPDACis a highly lethal form of cancerIn most patientsdetection is at an advanced stage and the outcome is poorThis project is directed towards development of a molecularly targeted ultrasound contrast agent with potential to detect early stage disease while still curableIn Phase I of this projectwe incorporated the engineered human single chain variable fragmentscFv ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Dual View Endoscopy for Colonoscopy

    SBC: Omniscient Imaging, Inc.            Topic: 102

    AbstractAn estimatedmillion colonoscopies are performed annually in the US at a cost of about $Bhowever current colonoscopes with forward vision fail to detectof precancerous polypsOverof the missed polyps are located on or behind numerous folds in the colon where they are hidden from the sight of a forward view colonoscopeIn this research proposalwe propose to complete our development of an imagi ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Affordable Reinforced Polymer Composite Structures with Embedded Electrical Interfaces

    SBC: Taylor & Lego Holdings, LLC / Rapid Composites            Topic: MDA12025

    The purpose of this program is to continue development of Affordable Reinforced Polymer Composite Structures with Embedded Electrical Interfaces for use in unmanned aerial systems (UAS) and apply that technology specifically to the Raytheon developed Coyote UAS. The proposed effort builds upon a successfully completed SBIR Phase I program performed by Taylor and Lego under contract to the Missile ...

    SBIR Phase II 2018 Department of DefenseNavy
  6. Compact Off-board Passive Target-Discriminator

    SBC: ANALYSIS DESIGN & DIAGNOSTICS INC            Topic: N131079

    A low power COBPTD node will be used to automatically detect and classify targets of interest. We will use target derived kinematics and a rule based classifier to classify high interest targets.

    SBIR Phase II 2014 Department of DefenseNavy
  7. Development of molecular assays for non-invasive bladder cancer detection

    SBC: NONAGEN BIOSCIENCE CORPORATION            Topic: 102

    DESCRIPTION provided by applicant Bladder cancer BCa is among the five most common malignancies worldwide In the US alone new BCa cases for are estimated at with estimated deaths at At presentation the majority of bladder tumors are non muscle invasive and can be treated by transurethral resection of the tumor however more than of patients with BCa will have a re ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Mitigation of Supersonic Aircraft Pod Aero-Optics

    SBC: MZA Associates Corporation            Topic: AF103001

    A technical plan is proposed for developing a supersonic pod-based application of virtual duct passive flow control for aero-optic mitigation. Virtual ducts have proven to be a highly effective tool for achieving aero-optic mitigation transonic flight up to Mach 0.8, and the proposed work seeks to leverage our extensive experience in designing and testing transonic virtual ducts to develop a unifi ...

    SBIR Phase II 2018 Department of DefenseDefense Advanced Research Projects Agency
  9. A device for rapid, painless, bedside muscle evaluation of children with neuromus

    SBC: Myolex Inc            Topic: 105

    DESCRIPTION provided by applicant The neuromuscular assessment of children is uniquely challenging Unlike examination of the heart or lung the complete bedside assessment of the neuromuscular system requires the active participation of the child and results must be evaluated in the context of normal child development and degree of cooperation Moreover neuromuscular disease severity is highl ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Portable, low power soil gas analyzer

    SBC: MESA PHOTONICS, LLC            Topic: 19a

    There is a need for soil gas analyzers to characterize subsurface biogeochemical processes by measuring simultaneously multiple gases that are signatures for specific processes. Instruments should be significantly more portable and require less power than what is currently available. The analyzers need to be suitable for field work and laboratory studies. How This Problem is Being Addressed: Rugge ...

    SBIR Phase II 2018 Department of Energy
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