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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Validation of a salivary miRNA diagnostic test for autism spectrum disorder

    SBC: Quadrant Biosciences Inc.            Topic: 103

    Autism spectrum disorder (ASD) is a continuum of neurodevelopmental characteristics that includes deficits in communication and social interaction, as well as restrictive, repetitive interests and behaviors. ASD is an increasing public health concern, with about 1 in 45 American children diagnosed with ASD in 2014, a 10-fold increase in prevalence over the past 40 years. The effect of ASD on both ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Electronic Optimization of Stem Cell Derived Human Cardiac Myocytes

    SBC: Cytocybernetics Inc            Topic: NHLBI

    Project Summary As part of the FDA approval process for novel therapeutic drugssafety screening demonstrating that the candidate drug does not have deleterious effects on the human cardiac action potential is requiredHealthy human heart cells are not available for such preclinical drug testingThere is currently no consensus on the best experimental approach to provide the most efficienteconomicala ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  3. STTR Phase II: Self-Health Management Informatics Platform: Improving Patient Engagement in Care Delivery

    SBC: SIPPA Solutions LLC            Topic: SH

    The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase II project is a patient-centric engagement process that offers the best chance for enabling a scalable approach towards achieving the triple aim of improving care quality and outcomes, controlling health care costs and utilization, and increasing patient satisfaction. Currently the national healthcare c ...

    STTR Phase II 2018 National Science Foundation
  4. STTR Phase II: HI-LIGHT- Solar Thermal Chemical Reactor Technology for Converting CO2 to Hydrocarbons

    SBC: Dimensional Energy Inc.            Topic: CT

    The broader impact/commercial potential of this STTR Phase II project will result in significant economic activity through the utilization of waste carbon dioxide. The photo-catalytic reactors funded in the project will lead to novel methods to chemically store energy from the sun. Each year, human activity releases 38 billion tons of carbon dioxide into the atmosphere. Dimensional Energy envision ...

    STTR Phase II 2018 National Science Foundation
  5. Automated Assessment of Leptomeningeal Collaterals on CT Angiograms

    SBC: Kitware, Inc.            Topic: 108

    AbstractThe primary goal of this study is to develop an automated scoring system of leptomeningeal collaterals based on CT angiographyCTAas a quantitative assessment of acute ischemic strokeLeptomeningeal collaterals provide an alternate path of blood flow in the setting of a proximal vessel occlusionThe presence and effectiveness of leptomeningeal collateralsi ecollateral statusvaries significant ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Mobile Augmented Screening Tool to Increase Adolescent HIV Testing and Linkage to Care

    SBC: Digital Health Empowerment, Inc            Topic: NICHD

    ABSTRACTAdolescents face increased HIV riskinfrequent testinginconsistent linkage to careand a lack of prevention related knowledgeWe propose to address this by completing and evaluating the Mobile Augmented ScreeningMAStool to increase youth HIV testing via a tablet based intervention in clinical settingsand then use text messages to facilitate linkage to care for those who test positiveand deliv ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Dual View Endoscopy for Colonoscopy

    SBC: Omniscient Imaging, Inc.            Topic: 102

    AbstractAn estimatedmillion colonoscopies are performed annually in the US at a cost of about $Bhowever current colonoscopes with forward vision fail to detectof precancerous polypsOverof the missed polyps are located on or behind numerous folds in the colon where they are hidden from the sight of a forward view colonoscopeIn this research proposalwe propose to complete our development of an imagi ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Enhanced Software Tools for Detecting Anatomical Differences in Image Data Sets

    SBC: Ligo Analytics            Topic: 105

    Project Summary Morphometric analysis is a primary algorithmic tool to discover disease and drug related effects on brain anatomy. Neurological degeneration and disease manifest in subtle and varied changes in brain anatomy that can be non-local in nature and effect amounts of white and gray matter as well as relative positioning and shapes of local brain anatomy. State-of-the-art morphometry meth ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Energy Efficient, Non-Silicon Digital Signal Processing (DSP)

    SBC: HYPRES, INC.            Topic: N17AT027

    Superconductor digital circuits, operating at very high clock speed, can directly process wideband digitized radio frequency (RF) signals. By integrating such digital processing circuitry together with superconductor analog-to-digital converters (ADCs), we propose to develop the next generation digital-RF receivers. Leveraging the recent development of multiple superconductor ADCs on the same chip ...

    STTR Phase II 2018 Department of DefenseNavy
  10. Laser and Rapid-thermal Crystallization of Low-defect GeSn and SiGeSn Layers for High Performance Infrared Detectors and Integrated Si-based Optoelectronic Devices

    SBC: EPITAXIAL LABORATORY INC            Topic: AF16AT28

    latereThis proposal describes the development of a process to synthesize low defect Ge1-xSnx and SiyGe1-x-ySnx layers on silicon and silicon-on-insulator (SOI) substrates through low thermal budget laser and rapid thermal annealing/crystallization for high performance mid-wave infrared (MWIR) photo detectors and integrated Si-based optoelectronic devices. In phase I, we demonstrated synthesis of G ...

    STTR Phase II 2018 Department of DefenseAir Force
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