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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. IND-enabling development of a biomimetic peptide drug for macular edema

    SBC: Asclepix Therapeutics, Inc.            Topic: NEI

    SummaryMacular edemaMEand diabetic macular edemaDMEwhich affects at leastmillion people in theUSare leading causes of blindness in people between the ages ofThe major problem in thesediseases is a leaky vasculaturewhich results in pooling of blood around the retinaThis blood can causeocclusion of vision as well as swelling and increased ocular pressure and detachment of the retinaThe effective the ...

    SBIR Phase II 2017 Department of Health and Human Services
  2. RetiVue DR, a point and shoot, non-mydriatic, widefield retinal camera for diabetic eye screening

    SBC: RETIVUE LLC            Topic: N

    Project Summary Over the past two decadesdiabetic retinopathyDRhas become the leading cause of adult blindness in the USaffectingof all diabetic patients and resulting in $million a year in direct medical costsVision loss due to DR is largely preventable and can be reduced by up towith appropriate eye screeningHoweverin the USless thanof diabetic patients receive a recommended yearly eye exam due ...

    SBIR Phase II 2017 Department of Health and Human Services
  3. Development and Commercialization of Predictive Biomarker Panel and In Office Kit for the Management of Diabetic Macular Edema

    SBC: OCULAR PROTEOMICS, LLC            Topic: N

    Abstract Diabetic Macular Edema DME is a vision threatening stage in Diabetic Retinopathy DR that can result in legal blindness The biochemical mechanisms that drive DME progression are not well understood and treatments address only portions of the disease pathology The available treatment options vary widely from injectable anti VEGF to injectable steroids to laser treatments and carry a ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. An innovative interactive mHealth smartphone app to improve reproductive health outcomes for minority male teens providing medically accurate information for prevention of pregnancy HIV and STIs

    SBC: MetaMedia Training International, Inc.            Topic: NCCDPHP

    Abstract MetaMedia and partner Healthy Teen Network will develop a mobile application aimed at reducing teen pregnancy and sexually transmitted infections STIs among Latino and African American men aged In the U S teen pregnancy teen births and STIs affect African American and Latino youth in greater proportion compared to other youth A comprehensive literature search revealed that ...

    SBIR Phase I 2017 Department of Health and Human Services
  5. Universal Crosswalk Diagrams for Better Confidence and Safety in Pedestrians Who Are Blind

    SBC: Touch Graphics, Inc.            Topic: na

    This project evaluates the effectiveness of Universal Crosswalk Diagrams (UCD), a new kind of street sign to aid pedestrians who are blind or have low vision. These small signs are mounted directly above existing Accessible Pedestrian Signals (APS), the pole-mounted buttons at street corners that pedestrians press to request information about the current status of the Walk/Don’t Walk indicator. ...

    SBIR Phase I 2017 Department of Health and Human Services
  6. T3 Platform: The Next Generation Tactile Tablet

    SBC: Touch Graphics, Inc.            Topic: na

    This project develops the T3 Platform, a system for creating, distributing, and displaying interactive, audio-tactile maps, graphs, games, and braille lessons. Built on the successful but outdated Talking Tactile Tablet (TTT) paradigm, this new approach makes some images accessible to those who can’t see well enough to use standard print graphics. T3 Platform includes four components: T3 Tablet, ...

    SBIR Phase I 2017 Department of Health and Human Services
  7. Touch-Responsive Models for Universal Access to Smithsonian Museums Exhibits

    SBC: Touch Graphics, Inc.            Topic: na

    This project develops new methods for fabricating replicas of museum artifacts and other 3D objects that describe themselves when touched, so that museums can create exhibits that are accessible to everyone, including visitors with visual impairments. Phase I demonstrated how ordinary capacitive touchscreens could be repurposed as sensors for determining locations of finger touches on 3D surfaces ...

    SBIR Phase II 2017 Department of Health and Human Services
  8. AVGN7, a Novel Gene Therapeutic for Treating Cancer Cachexia

    SBC: Aavogen, Inc.            Topic: 102

    PROJECT SUMMARYThe skeletal muscle wasting that occurs with cancer cachexia compromises quality of life and is both directly and indirectly responsible for cancer mortalitiesTumor derived and tumor responsive factors as well as many therapeutics themselves contribute to the cachectic statealthough nutritional support has little if any positive effect on restoring striated muscle mass or functionTh ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Development of a Novel Plasma Based Microsatellite Instability Diagnostic for Guiding Immunotherapy

    SBC: Personal Genome Diagnostics Inc.            Topic: 102

    Abstract Immune checkpoint inhibitors have recently emerged as a revolution in cancer care providing the potential for durable response and improved survival for numerous cancer patients across multiple cancer types However only of patients who are treated with checkpoint inhibitors have responded in most cancer types necessitating biomarker assays that can reliably and accurately ident ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Development of a companion diagnostic to predict response to cetuximab in patients with head and neck squamous cell carcinoma

    SBC: Biomarker Strategies, LLC            Topic: 100

    ABSTRACT Head and neck squamous cell carcinoma HNSCC is the world s th leading cause of cancer accounting for of cancer mortality For many other cancers molecular characterization has led to sub classification of disease based on the status of oncogenic drivers in signal transduction pathways leading to the development of molecularly targeted agents MTAs targeting specific dysregulate ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
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