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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Design Automation Software for Biomimetic Surface Presentation with DNA Origami

    SBC: PARABON NANOLABS, INC.            Topic: CBD12103

    A development program is proposed for a design automation software package that enables the generation of complex surfaces, with user defined or automated definition of point charge and hydrophobic/hydrophilic properties, using DNA origami as a presentation substrate. Building upon Parabons existing software for DNA origami design, this project will result in software that can be used to design a ...

    SBIR Phase II 2014 Department of DefenseOffice for Chemical and Biological Defense
  2. Regenerable, heat-Abating, humidity-Neutralizing, Carbon diOxide Removal System (RANCOR) Phase II

    SBC: Paragon Space Development Corporation            Topic: CBD12106

    In Phase I RANCOR successfully demonstrated an innovative enabling humidity control technology to provide very low humidity air to water sensitive, fully reusable CO2 adsorbents. The use of adsorbents enables complete reusability/rechargability and reduces the total heat load on the SCBA to the point where ice or other cooling systems will no longer be required. In Phase II Paragon will introduce ...

    SBIR Phase II 2014 Department of DefenseOffice for Chemical and Biological Defense
  3. Porphyrin-DNA Origami Constructs as Bioscavengers for Organophosphates

    SBC: PARABON NANOLABS, INC.            Topic: CBD14104

    The recent use of organophosphate (OP) nerve agents against combatants and civilians in Syria has validated the importance of developing new drugs and biologics that sequester and catalytically degrade organophosphate (OP) nerve agents in the body before they cause morbidity and mortality. We propose to develop a method for the sequestration of OP simulants via porphyrin-DNA constructs. Construc ...

    SBIR Phase I 2014 Department of DefenseOffice for Chemical and Biological Defense
  4. Microhydrogel Depot for Sustained Delivery of Prophylactic Bioscavenger

    SBC: Luna Innovations Incorporated            Topic: CBD13107

    Countering the threat of intoxication by organophosphorus nerve agents is an important mission for homeland security. Currently, the most promising strategy is to bioscavenge the agents using injectable plasma-derived butyrylcholinesterase (BuChE) that has low substrate specificity and may offer a broad spectrum protection against OP agents. Human plasma-derived BuChE at 400mg IV dose is prophylac ...

    SBIR Phase II 2014 Department of DefenseOffice for Chemical and Biological Defense
  5. Carbon Based Nano-Additives for Chemically and Biologically Protective Polymeric Nanocomposites

    SBC: ATS-MER, LLC            Topic: CBD03304

    The development of carbon-based nano-additive bound polymers with enhanced adsorption capacity and reactivity for the neutralization of chemical and biological warfare agents could cause substantial saving of life during CBWA threats. In the Phase I pr

    SBIR Phase II 2004 Department of DefenseOffice for Chemical and Biological Defense
  6. Reversible Molecular Closure System for Shelters and Clothing

    SBC: Luna Innovations Incorporated            Topic: CBD04110

    Luna will develop a hermetic closure system for use on combat uniforms and shelters that require protection from chemical and biological (CB) warfare agents. Despite great advances in high barrier fabrics, selectively permeable membranes, and unique chemical absorbent technologies, closures for clothing and shelters still possess the greatest risk for chemical or biological breach. Instead of mo ...

    SBIR Phase I 2004 Department of DefenseOffice for Chemical and Biological Defense

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