Award Data

DESCRIPTION provided by applicant Hospital acquired microbial infections are the fourth largest killer in America taking lives and adding $ B to hospital costs The emergence of drug resistant microbes has further amplified public health concern Fungi are prolific producers of anti microbial secondary metabolites SM and since the turn of the century have provided of bioactive m ...

DESCRIPTION provided by applicant In the first phase of this project it was shown that by utilizing innovative technologies it was possible to allow below the knee amputees to walk and run using a single powered prosthetic device In the second phase of this project it will be shown that the key technological advancements and optimizations will allow the a single powered device to perform wa ...

DESCRIPTION provided by applicant The goal of this STTR Phase II collaboration between Purdue University and bioVidria Inc is to commercialize disruptive new technology for protein chromatography and then maximize its impact by serving the fastest growing segment of the pharmaceutical industry protein drugs The product is a reversed phase chromatography column that uses silica particles of ...

DESCRIPTION provided by applicant Amyotrophic lateral sclerosis ALS or Lou Gehrigandapos s disease is a fatal neurodegenerative disease with a typical lifespan of years after diagnosis The initial symptoms can be similar to many other neurologic disorders and often begin with limb weakness muscle fasciculations or increasing difficulties in speech or breathing No definitive diagnost ...

DESCRIPTION provided by applicant Alternative nanomaterial and gene transfer solutions are needed to access the potential held in intracellular imaging biopharmaceuticals gene therapy and stem cell research Delivery of small and macromolecules including nucleic acids drug molecules imaging agents peptides antibodies and enzymes into cells is criti ...

DESCRIPTION provided by applicant The objective of this application is to introduce a novel simplified low cost technology to address the broad need of detecting RNA pathogens directly in crude samples such as blood Traditional RT PCR requires purifying the RNA which increases the cost time and risk of cross contamination We intend to reduce or eliminate the purification step by producin ...

DESCRIPTION (provided by applicant): The goal of this Phase II Small Business Innovative Research (SBIR) application is to fill a major void in the undergraduate neuroscience curriculum: A lack of educational materials that give students the opportunity to learn neuroscience by working hands-on with neuroimaging data. The NeuroVisions: Teaching neuroscience with neuroimaging data project will cre ...

Location P.O. BOX 755 WEST KINGSTON, RI 02892 United States 9R44MH086129-02A1 $748 985.00 2 008 A Stage-Based Expert System for Teen Dating Violence Prevention Department of Health and Human Services National Institutes of Health SBIR Y N N PHS2007-2 Pro- ...

DESCRIPTION (provided by applicant): BCR Diagnostics, Inc. (BCR) has recently developed and patented a technology platform for engineering fluorogenic functionality into living Bacillus spores. Fluorogenic spores (F-spores) produced at BCR appear to be phy siologically identical to normal spores except for performing as self reporters of initial germination events. Considering the unique features ...

DESCRIPTION provided by applicant The proposed work is directed at the commercialization of a stretchable microelectrode array BMSEEDandapos s sMEA a new tool that provides enhanced capabilities to simultaneously interface mechanically and electrically with cell cultures in vitro The mechanical stretching of neurons in the brain or spinal cord is often te root cause of traumatic brain injur ...