Award Data

Long-duration wide-area surveillance missions increasingly are space-based. MEO orbits offer space-based radar systems more time on station, but require very large array apertures on the order of 100m in diameter. Achieving larger apertures with smaller, lighter launch packages and stable on-orbit pointing is a challenge that E-Textiles promises to meet. Textile processes can be used to achieve a ...

DESCRIPTION provided by applicant This Phase II project will develop a novel synthetic microparticle vaccine for malaria using the T BT epitopes of the circumsporozoite CS protein of Plasmodium falciparum the causative agent of human malaria There is no approved vaccine for malaria a disease that causes up to million new infections and million deaths each year in the developing wor ...

DESCRIPTION provided by applicant Lyme disease LD caused by the Ixodes tick borne spirochete Borrelia burgdorferi Bb is the most common vector borne disease in the United States Despite public health preventive measures the annual confirmed case incidence has risen to over the vast majority of which occur in the Northeast Disseminated infection causes disease in the skin heart ...

DESCRIPTION provided by applicant Hospital acquired microbial infections are the fourth largest killer in America taking lives and adding $ B to hospital costs The emergence of drug resistant microbes has further amplified public health concern Fungi are prolific producers of anti microbial secondary metabolites SM and since the turn of the century have provided of bioactive m ...

DESCRIPTION provided by applicant Current testing for Lyme disease is suboptimal because it requires two assay platforms including one with subjective interpretation of results and because it has lower sensitivity in the early stage of the illness Infection with Borrelia burgdorferi the causative agent of Lyme disease is transmitted by the bite of an Ixodid tick and results in uniformly lo ...

Sonalysts will research and develop a robust military message profiler to permit automated local routing of incoming organizational messages transmitted to an activity by military messaging systems. Used at activities ashore and afloat, the profiler will parse and decode incoming messages and compare them with administrator and user-managed routing profile schema to determine which groups of end-u ...

Recent high usage of helicopters in Iraq and Afghan theatres underscores a need for improvements in rotorcraft safety and reliability. Rotor induced vibrations contribute significantly to airframe fatigue, electronic component failure, and pilot workload. In current generation rotorcraft, vibration attenuation is achieved through either airframe mounted tuned-absorbers or active vibration control ...

DESCRIPTION (provided by applicant): The blood-brain barrier (BBB) represents both a safeguard against the penetration of physiologically harmful substances into the central nervous system (CNS), as well as a considerable hurdle to the delivery of therapeu tic agents. A technology allowing safe, targeted, reversible opening of the BBB would potentially revolutionize both the study and treatment of ...

DESCRIPTION provided by applicant All forms of diabetes are characterized by the death of insulin producing cells In Type diabetes T D this leads to the reliance on exogenous insulin for survival Death of cells is silent it cannot be detected in vivo until it has progressed to such an extent that metabolic function is impaired The loss of cells has only been assessed by functiona ...

The DoD requires an increase in performance and density of solid propellants for use on boost, strategic and tactical missile systems. Attaining ingredients with higher energy and density while simultaneously maintaining satisfactory physical properties is extremely challenging. Current low-cost oxidizer ingredients such as Ammonium Perchlorate (AP) are incapable of imparting the desired performan ...