Award Data

Long-duration wide-area surveillance missions increasingly are space-based. MEO orbits offer space-based radar systems more time on station, but require very large array apertures on the order of 100m in diameter. Achieving larger apertures with smaller, lighter launch packages and stable on-orbit pointing is a challenge that E-Textiles promises to meet. Textile processes can be used to achieve a ...

DESCRIPTION provided by applicant Hospital acquired microbial infections are the fourth largest killer in America taking lives and adding $ B to hospital costs The emergence of drug resistant microbes has further amplified public health concern Fungi are prolific producers of anti microbial secondary metabolites SM and since the turn of the century have provided of bioactive m ...

DESCRIPTION provided by applicant In the absence of effective approved drugs or vaccines vector control remains the only means of intervention for many against mosquito borne diseases This problem grows more complex with the recent establishment of multiple exotic mosquito species and mosquito borne pathogens Furthermore changing climate conditions are predicted to alter the traditional ra ...

DESCRIPTION (provided by applicant): Cervical cancer is one of the most common cancers affecting women and is a worldwide health problem. Unlike most cancers, cervical cancer is caused by a virus - the human papillomavirus (HPV). Two preventative vaccines against HPV were recently licensed in the United States. Merck and Co. developed a vaccine called Gardasil(tm) and GlaxoSmithKline has develop ...

DESCRIPTION (provided by applicant): The goal of the proposed research is to demonstrate that Inter-alpha serine protease inhibitor proteins (IaIp) are an effective therapy for sepsis. In sepsis, normally high plasma levels of IaIp drop dramatically in

The utilization of Mixed Base Hydrogen Peroxide is well documented in its application for the COIL and ABL Systems. During Phase I, VITOK determined a variety of recipes that could be utilized with the mixing of caustics and H2O2 while developing them in a system that is portable, air-transportable, supportable with a small logistics footprint. Initial essential design of the general skid arrang ...

DESCRIPTION provided by applicant Genital tract infection with Neisseria gonorrhoeae gonorrhea does not induce a state of specific protective immunity and can be acquired repeatedly Despite public health measures the disease persists at an unacceptably high frequency there is no vaccine against it and resistance even to the latest generations of antibiotics continues to emerge Recent fin ...

DESCRIPTION (provided by applicant): SCR, Inc. (Louisville, KY) has developed a long-term implantable counterpulsation device (CPD) to treat heart failure (HF) patients who may be responsive to a milder form of cardiac assist. The CPD is 32-ml stroke vol ume, valveless pneumatically-driven blood sac with a single inflow/outflow cannula. The sac fits ergonomically in a pacemaker pocket' and the ...

DESCRIPTION (provided by applicant): Sickle Cell Disease (SCD) is a genetic abnormality of red blood cells (RBC) that affects over 70,000 people in the United States, or approximately 1 in every 500 African-Americans. With current therapies, the mortality in the United States is 50% by age 40. SCD is a chronic, debilitating disease associated with frequent painful crises, acute chest syndrome, st ...

DESCRIPTION (provided by applicant): Warfarin is the most commonly used oral anticoagulant medication. Because an individual's proper warfarin dose is difficult to assess, most physicians initiate therapy at a standard dose and follow up with an INR blood test to ensure the medicine is working properly. Unfortunately, therapeutic warfarin doses vary significantly from patient to patient, so that ...