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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Improving treatment options and outcomes in fungal keratitis

    SBC: TranZ Biosciences LLC            Topic: N

    ABSTRACT Fungal keratitisprimarily caused by CandidaFusariumor Aspergillus speciesis a leading cause of blindness among corneal diseasesAmphotericin BAmBremains the gold standard in the treatment of Candida keratitis and is also the fallback option for other corneal fungal infectionsAlthough widely used off label in ocular infectionsophthalmic AmB formulations are not available commerciallyThe com ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Next Generation Tools for Onsite Monitoring and Treatment of Drug of Abuse-Dependent Persons

    SBC: SensoDX II, LLC            Topic: NIDA

    Abstract Opioid abuse disorder (OAD) affects 2.1 million of Americans annually resulting in overdoses numbering in the tens of thousands and skyrocketing rates of mortality. In addition to its enormous social impact, OAD carries a multi-billion-dollar price tag that includes $78.5 billion, specifically for health care and other costs related to prescription opioid abuse and misuse. Although effect ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Resveratrol as a Corneal Pain Therapeutic

    SBC: TED'S BRAIN SCIENCE INCORPORATED            Topic: N

    More thanindividuals undergo laser vision correction surgery each year in the United Statesincluding laser assisted in situ keratomileusisLASIKand photorefractive keratectomyPRKThese procedures damage the nerves in the corneal epithelium causing intense acute pain that most patients rate as greater thanon ascalemany report the pain to beunbearableeven after analgesic treatmentWhile virtually all p ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Transcutaneous auricular neurostimulation for neonatal abstinence syndrome

    SBC: SPARK BIOMEDICAL INC.            Topic: R43

    Neonatal abstinence syndromeNASis a condition in which infants undergo withdrawal after exposure to prescription or non prescription opioids such as methadone or heroin in uteroNAS babies exhibit hyperirritability of the central nervous system and respiratorygastrointestinaland autonomic symptomsThese symptoms usually appear withintohours after birthAs ofan infant with NAS was born everyminutes in ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Novel Strategies for Development of a Multiplexed Test with Expanded Content for Spinal Muscular Atrophy

    SBC: ASURAGEN, INC.            Topic: 102

    SummaryThe overall goal of this project is to develop a cost effective multiplexed diagnostic test for spinal muscular atrophySMAto rapidly and accurately analyze multiple classes of disease causingdisease modifying DNA variantsand carrier status markersUltimatelythe proposed test will have a far reaching impact by expanding the identification and stratification of patients who may benefit from ne ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Rapidly Integrated Tactical Communications Payload

    SBC: CESIUMASTRO INC            Topic: N181090

    The major challenge in constellation-wide deployment of tactical payloads in low-Earth orbit (LEO) lies in achieving the performance requirements that are imposed by constellation dynamics while maintaining a design simplicity that is compatible with large-scale production, along with typical constraints on size, mass, and power consumption. Cesium’s proposed solution is a small reconfigurable p ...

    SBIR Phase II 2019 Department of DefenseNavy
  7. Development of a rapid diagnostic assay for Myasthenia Gravis

    SBC: ATTOGENE CORPORATION            Topic: 101

    Project Summary AbstractThe physiological effect of autoantibody binding to the motor endplate junction nicotinic acetylcholine receptorsAchRcauses numerous symptoms associated with Myasthenia GravisMGand is characterized by drooping of one or both eyesblurred or double visionchange in facial expressiondifficulty swallowingshortness of breathimpaired speech and weakness of muscle functionIn some c ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Ad-Hoc Ground Based Counter-Fire System

    SBC: HYPERION TECHNOLOGY GROUP INC            Topic: N142086

    This proposal addresses the development of a Command Post and Acoustic Listening Posts for performing detection and automatic geo-location and classification of transient acoustic sounds associated with the firing of weapons, especially rockets, mortars, and artillery and the corresponding munitions impacts. Key components of the system are rugged low-noise infrasound sensors, state-of-the-art aco ...

    SBIR Phase II 2019 Department of DefenseNavy
  9. Enhanced UHSS Casing for Penetrating Munitions

    SBC: Shear Form Inc            Topic: AF191082

    In Phase I, Shear Form, Inc will apply a severe plastic deformation (SPD) processing technology to ultra-high strength steels (UHSS), specifically 4340M and AF 9628, to enable penetration improvement for munitions casings. Equal channel angular extrusion (ECAE), a fully scalable SPD method, will be used to process the steels under ausforming conditions. This will facilitate microstructural enginee ...

    SBIR Phase I 2019 Department of DefenseAir Force
  10. Improving Repair of Female Congenital and Reproductive Anomalies

    SBC: Biotex, Inc.            Topic: NICHD

    Project Summary The overall goal of this SBIR proposal is to develop a novel vaginal stent for use in pediatric and adult populations. There are many girls and women born with congenital gynecologic abnormalities requiring surgical reconstruction of their vaginal cavities. There are also women who have very shortened or scarred vaginas after pelvic surgery or radiation treatment for cancer. Vagina ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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