Award Data

Bone marrow transplant (BMT) is an extraordinarily rapidly growing field, and the number of transplants in the U. S. is expected to grow from a current rate of 15,000 per year to over 100,000 per year by 1995. This rapid expansion is due to the diversity in the types of bone marrow transplantation procedures and the number of clinical procedures that can be benefitted by a BMT. Major limiting fact ...

In vitro expansion of hematopoietic cells finds many applications in the clinic. This technique hasexpanding CD34+ cells for transplantation/re infusion, although most of the technology has consistedcultures in which there is variable CFUGM expansions and failure to maintain LTC IC (long term cultuThe Investigators have found that perfusion cultures of bone marrow mononuclear cells result in expaC ...

As the ability to communicate with the health care system becomes more important, there isa risk that minority populations, particularly non-English speaking and undeserved persons, will fallfurther behind in the level of care they receive. We are currently developing a general healthcare planfor its member companies, expected to begin in April 1994, and to be fully insured and provided inpartners ...

The small spacecraft power system proposed in this program provides significant advantages over state-of-the-art systems including: (1) use of a high efficiency (25%-35%) AMTEC, static power conversion system, (2) reduced planform area, and vulnerability, (3) mass efficient phase change material for thermal energy storage during solar eclipse periods, (4) high reliability with no vibration, (5) si ...

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The project objective is to test the feasibility of new network protocols for integration of a large collection of widely distributed heterogeneous databases and object data respositories into a unified system. Data contained in these databases will include text, graphics, sound, video, etc. The project will provide 2 kinds of services: 1. Index services to increase the ease and efficiency of loca ...

Electrical management of potentially lethal arrhythmias has been found to dramatically improve survcandidates at risk of sudden cardiac death. Over 40,000 Implantable cardioverter/defibrillators (ICDsince initial FDA approval in 1985. False positive delivery of shock remains a major problem and newdesigned with more sophisticated arrhythmia detection schemes and tiered-therapy protocols. We willst ...

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NEW METHODOLOGIES ARE BEING DEVELOPED FOR INTERRUPTING THE LYME DISEASE TRANSMISSION CYCLE, INCLUDING THE USE OF ACARICIDES IN REDUCING AN INFECTED TICK POPULATION, CONTROL OF PEROMYSCUS SPP. BY ENVIRONMENTAL MANIPULATION AND RODENTICIDAL TREATMENT, AND DEER POPULATION MANAGMENT. A SYSTEMIC, ORALLY ADMINISTERED ACARICIDE EFFECTIVE IN KILLING TICKS, (PARTICULARLY IMMATURE STAGES OF IXODES DAMMINI), ...