Award Data

Nevada Composites has developed Green-Aero(sm) toolinglightweight ceramic tooling that is stable under high pressure and long-duration cure cycles and can be washed out with water after cures to 370C (700F). Tools, whether single-sided or washout, have a composite-compatible CTE, provide tight tolerances, are reproducible, are stable to storage under ambient conditions, and are of affordable cost. ...

We are developing a platform for pharmacometric data analysis workflow that is much more flexible and efficient than anything else on the market. This will be accomplished by (1) developing new functions within Stan, a widely used, open-source, probabilistic programming language and Bayesian inference engine, for computationally efficient data analysis using complex differential equation models, ( ...

Project Summary Abstract Mitochondrial dysfunction causes mitochondrial diseases and is tightly linked to aging and neurodegenerative disorders such as Parkinsonandapos s and Alzheimerandapos s Recent discoveries support that mitochondrial dysfunction can be overcome to treat age related decline Cytegenandapos s hypothesis is that exercise induces the secretion of blood borne proteins that act ...

Project Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...

Project Summary Abstract Bacterial keratitisBKis an infection of the cornea thatif left untreatedcan cause blindnessStaphylococcus aureusSaStreptococcus pneumoniaeSpand Pseudomonas aeruginosaPaare three major causes of BK in North AmericaSymptoms of BK include painrednessinflammationand opacity of the affected cornea and loss of visual acuityAmebaGone IncAGpartnered with UW Madison Department of O ...

An integrated measurement sensor for carbon-carbon (C-C) structures is needed for testing in arc jet facilities to meet testing needs for current and future hypersonic flight systems. A commercial-off-the-shelf (COTS) high frequency response pressure sensor and a fabricated temperature, heat flux, and recession sensor built directly into a C-C substrate will be integrated into a test article for ...

The proposed Phase I effort is to complete a feasibility review of all innovative technology options that can be implemented in Phase II in order to evaluate, reverse engineer, reengineer, design, draft, fabricate, machine, coat, assemble and test facsimiles of foreign like weapons described in the topic announcement. McNally's solution is based on our years of experience in reverse engineering s ...

Nalas Engineering and Johns Hopkins University collaborated in a Phase I STTR program to study reactive mixtures of HI3O8 and nanocomposite fuels previously developed by the Weihs Group. These fuel/oxidizer mixtures are uniquely able to simultaneously produce heat and biocidal iodine gas, a combination designed to destroy biological weapons. The team at Nalas focused on evaluating conditions for p ...

Current Naval Air Systems imagery exploitation systems are fed new images from high speed data streams but have limited organic system file storage capability. With no built in logic to manage the storage volume, a first-in-first-out default overwrite situation often results, which hampers mission planning or results in planners having to expend time manually searching external libraries for neede ...

Surface ship ASW personnel will go for long stretches at sea without conducting ASW operations, which results in skill degradation. The Navy has embedded training in operational systems for decades but has never closed the loop between the training and operator performance. In order to address this need, Sonalysts, Inc. proposes to develop an innovative Gamification Training Architecture (GTA). Th ...