Award Data

Nevada Composites has developed Green-Aero(sm) toolinglightweight ceramic tooling that is stable under high pressure and long-duration cure cycles and can be washed out with water after cures to 370C (700F). Tools, whether single-sided or washout, have a composite-compatible CTE, provide tight tolerances, are reproducible, are stable to storage under ambient conditions, and are of affordable cost. ...

We are developing a platform for pharmacometric data analysis workflow that is much more flexible and efficient than anything else on the market. This will be accomplished by (1) developing new functions within Stan, a widely used, open-source, probabilistic programming language and Bayesian inference engine, for computationally efficient data analysis using complex differential equation models, ( ...

Project Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...

Nalas Engineering and Johns Hopkins University collaborated in a Phase I STTR program to study reactive mixtures of HI3O8 and nanocomposite fuels previously developed by the Weihs Group. These fuel/oxidizer mixtures are uniquely able to simultaneously produce heat and biocidal iodine gas, a combination designed to destroy biological weapons. The team at Nalas focused on evaluating conditions for p ...

Current Naval Air Systems imagery exploitation systems are fed new images from high speed data streams but have limited organic system file storage capability. With no built in logic to manage the storage volume, a first-in-first-out default overwrite situation often results, which hampers mission planning or results in planners having to expend time manually searching external libraries for neede ...

Surface ship ASW personnel will go for long stretches at sea without conducting ASW operations, which results in skill degradation. The Navy has embedded training in operational systems for decades but has never closed the loop between the training and operator performance. In order to address this need, Sonalysts, Inc. proposes to develop an innovative Gamification Training Architecture (GTA). Th ...

ABSTRACT Thetis plans to investigate TP an innovative and potential first in class therapeutic agent as an oral therapy for the induction and maintenance of remission of intestinal inflammation symptoms in ulcerative colitis UC patients While the precise etiology of UC is unknown it is thought to result from an inappropriate inflammatory response to commensal gut bacteria in genetically ...

Checkpoint inhibitor CPI therapy has transformed treatment of solid tumors Clinical responses in the range of with prolonged survival have been reported for tumors such as malignant melanoma and non small cell lung cancer that previously had poor response rates and dismal prognoses Current therapies block PD PD L and CTLA and there are other targets being developed such as LA ...

SciGenesis will apply its FR-technology to nylon-only and nylon/cotton (50/50) blended yarns to demonstrate the feasibility of this technological platform at the individual yarn stage (i.e. pre-woven). The unique FR chemistry that SciGenesis has developed encompasses char promoting agents, heat reflective particles, Lewis-acid catalysts and a laundering durable binding system. Implementing this ...

Mountain descent test procedures that replicate conditions found in severe mountain environments are essential in identifying the limitations of current and future vehicle systems. Current tests have failed to reproduce these severe, realistic conditions resulting in deficiencies in overall vehicle performance. In Phase I a prototype Brake Fade Advance Warning System (BFAWS) and mountain descent r ...