Award Data

DESCRIPTION (provided by applicant): The sequencing of genomes has generated a huge amount of data still to be annotated. Computational methods are available to detect putative transcriptional promoter regions, but they are not 100% efficient and must be confirmed by experimentation. Unfortunately the wet-bench procedures that are currently available to study promoters are time-consuming, laborio ...

Manning Applied Technology proposes to develop a handheld infrared spectrometer, ideally suited to detection of airborne chemical agents at and below permissible exposure limits. This approach offers unmatched sensitivity and specificity for detection of all types of chemical vapors. The instrument is modular, rugged, compact and highly sensitive. Volume pricing will be less than $1000 each. ...

Ocean waves are well-known to be the most hazardous of ocean environmental conditions affecting vessel operations. The vast majority of incidents responded to by the U.S. Coast Guard, injuries and fatalities, and damage to or sinking of vessels (particularly small craft) are wave-related. Recognizing the considerable spatial and temporal variability of waves in coastal areas, research will desig ...

Commercial-scale marine aquaculture has the potential to balance the increasing demand for high-quality seafood products with the harvest capacity of our nation¿s oceans. However, water reuse in recirculating aquaculture systems (RAS) is limited by the accumulation of nitrate (NO3), which is toxic to many species in high concentrations. Therefore, NO3 removal by denitrification presents a press ...

INADEQUATE STARTER FEEDS SEVERELY HOLD BACK NEW AQUACULTURE ENTERPRISES SUCH AS PRESENT ATTEMPTS TO RAISE FISHES WHOSE LARVAE DEVELOP FROM SMALL EGGS AND HAVE VERY "DIFFICULT" FOOD REQUIREMENTS. INERT LARVAL FEEDS HAVE NOT SUCCESSFULLYELIMINATED THE STRICT DEPENDENCY ON NATURAL FORAGE DURING THE CRITICAL POST-LARVAL STAGE AFTER YOLK ABSORPTION AND BEFORE THE DEVELOPMENT OF A DIGESTIVE SYSTEM WITH ...

DESCRIPTION (provided by applicant): Infigen will use SBIR grant support to develop a model for evaluating the molecular events associated with cellular reprogramming that enables early determination of a cell's probability of developing into a desired organism or tissue. No such model has been reported to date, impeding rational approaches to development of emerging health care applications depen ...