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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. TLR Signal Inhibition: A Novel Therapeutic Paradigm

    SBC: INTERTHYR CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Interthyr Corporation (IC) is requesting an Advanced Technology Phase II STTR award to develop a novel agent with a new therapeutic paradigm: Inhibition of Toll-like receptor (TLR) expression and signaling in non-immune cells. In pursuing studies based on its Phase I award, IC has shown that a lead compound from a family of tautomeric cyclic thiones (TCTs), phe ...

    STTR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  2. Development of a Novel Method for Inhibiting Atherosclerosis in Diabetes

    SBC: VASCULAR PHARMACEUTICALS            Topic: N/A

    DESCRIPTION (provided by applicant): The long term objective of the proposed studies is to develop a monoclonal antibody that can be administered safely to patients with diabetes that will inhibit atherosclerosis. Insulin-like growth factor-I has been implicated in the initiation of the proliferative phase of atherosclerotic lesion development but inhibiting IGF-I receptor activity may lead to tox ...

    STTR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  3. Fast Spectral Imaging Device For Tumor Margin Mapping

    SBC: Zenalux Biomedical, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The American Cancer Society estimates that a total of 240,430 new breast cancers were diagnosed in 2007 (178,400 new cases of invasive breast cancer, and 62,030 new cases of in situ breast cancer). Approximately 180,000 of these patients undergo breast conserving surgery (BCS), also called lumpectomy. Multiple recent studies show that a staggering 20-70% of the ...

    STTR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  4. A Novel Drug for Septicemia Targets A1 ARs

    SBC: ENDACEA, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Despite the availability of newer antimicrobial agents, improved supportive care, and the introduction of an FDA approved adjunctive therapy for sepsis, (Xigris(r), drotrecogin alfa), the mortality rate for severe sepsis and septic shock of 30-60% remains high. Endacea, Inc. (Research Triangle Park, NC) approaches sepsis with a proprietary diagnostic/biomarker ...

    STTR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  5. A Novel Therapy for Staphylococcal Enterotoxin B Poisoning

    SBC: SOYMEDS INC            Topic: N/A

    DESCRIPTION (provided by applicant): Staphylococcus aureus is a significant human pathogen which can produce a variety of toxins, including the exotoxin, staphylococcal enterotoxin B (SEB). SEB is highly toxic in small doses, and the compact structure of this protein makes it resistant to heat and denaturation. The combination of toxicity and stability caused this toxin to be selected for weaponiz ...

    STTR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  6. A Universal Brain Atlas for Implanting and Managing Deep Brain Stimulators

    SBC: Neurotargeting, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Neurotargeting, LLC proposes to develop the technical support infrastructure as well as clinical tools for a commercial software product that will provide a global service for the medical community involved in deep brain stimulator (DBS) therapy. Specifically, this Phase I study will explore the use of a physiological atlas database that can interface with a nu ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  7. N/A

    SBC: ACCURATE AUTOMATION CORPORATION            Topic: N/A

    N/A

    STTR Phase II 2000 National Aeronautics and Space Administration
  8. N/A

    SBC: RESODYN CORPORATION            Topic: N/A

    N/A

    STTR Phase II 2000 National Aeronautics and Space Administration
  9. N/A

    SBC: Receptorpro, Inc.            Topic: N/A

    N/A

    STTR Phase II 2000 Department of Health and Human ServicesNational Institutes of Health
  10. Exercise Stress Cardiac Magnetic Resonance

    SBC: EXCMR, LTD            Topic: N/A

    DESCRIPTION (provided by applicant): Exercise stress testing with imaging is widely used to detect heart disease, but current stress imaging systems suffer from false positives that may lead to unnecessary invasive testing, and false negatives that may miss disease detection until a serious event occurs. Thus, consistently accurate stress imaging remains an important target for technology developm ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
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