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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Microcapillary Quartz Sensors for Screening Injectability of High Concentration Protein Formulations

    SBC: Qatch Technologies, LLC            Topic: None

    The objective of this SBIR Phase I proposal is to determine the feasibility of viscosity characterization of high concentration protein formulations (HCF) by QATCH’s microcapillary quartz technology. HCFs are non-Newtonian fluids with shear-thinning behavior and they are administered to patients by subcutaneous or muscular injections. The injectability of HCFs depends on the viscosity at high-sh ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  2. Habitat ISHM Using Non-Invasive Load Management Analytics

    SBC: MHI Energy Information Solutions, LLC            Topic: H6

    We believe a robust approach to integrated system health management (ISHM) design is the application of redundancy. Redundancy is often thought of in terms of hardware; however, functional, analytic, and information redundancy strategies should also be considered.  Modeling sensor information is invaluable for diagnostics and critical path analysis. A total system approach is an efficient mea ...

    SBIR Phase I 2018 National Aeronautics and Space Administration
  3. Smart Fault Management (SFM)

    SBC: TMC Technologies of WV Corp            Topic: S5

    The Phase I of the SBIR “Smart Fault Management” project aims to demonstrate how the fault management process can be innovated by exploiting concepts from a combination of well-established and emerging disciplines such as Bayesian Statistics, GPU-accelerated numerical simulations, Data Science, and Machine Learning that are disrupting the current status quo in many scientific and engin ...

    SBIR Phase I 2018 National Aeronautics and Space Administration
  4. Fabric Reinforced Metal Matrix Composite

    SBC: TOUCHSTONE RESEARCH LABORATORY LTD (INC)            Topic: Z3

    The proposed research aims to develop a metal matrix composite (MMC) fabric that, when combined with additive manufacturing, will lead to weight reduction, increased structural performance, and reduce fabrication costs of structural components within launch vehicles. The approach focuses on developing a MMC fabric that will be used to selectively reinforce metallic components that are subjected to ...

    SBIR Phase I 2018 National Aeronautics and Space Administration
  5. Intelligent Electronic Speed Controller

    SBC: 4D TECH SOLUTIONS, INC.            Topic: A1

    This project will result in the commercialization of an Intelligent Electronic Speed Controller (IESC) for use on Unmanned Aerial Vehicles (UAVs). The IESC will advance the state-of-the-art of health-state awareness. This will be achieved through the integration of propulsion system health monitoring sensors that - in unison with an Intelligent Rule Set - will be able to monitor system and compone ...

    SBIR Phase II 2018 National Aeronautics and Space Administration
  6. SWIFT ActiveScreener research and development of an intelligent web based document screening system

    SBC: Sciome LLC            Topic: NIEHS

    Project Summary More than systematic reviews are performed each year in the fields of environmental health and evidence based medicine with each review requiring on average between six months to one year of effort to complete In order to remain accurate systematic reviews require regular updates after their initial publication with most reviews out of date within five years In the sc ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Implantable iontophoresis chemotherapy delivery device for direct infusion of gemcitabine into pancreatic adenocarcinoma Device development and First in Human clinical trial

    SBC: Advanced Chemotherapy Technologies            Topic: 102

    PROJECT SUMMARY Advanced Chemotherapy Technologies ACT has developed a proprietary implantable iontophoretic device that facilitates the infusion of chemotherapy agents directly into a cancer tumor minimizing toxic exposure to the vascular system and other organs ACT is focusing specifically on treating pancreatic cancer with gemcitabine for this proposal Pancreatic cancer has a five year sur ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Novel PhageLock assay to measure hepcidin for clinical monitoring

    SBC: AFFINERGY, LLC            Topic: 400

    SUMMARY ABSTRACT Hepcidin is the peptide hormone responsible for regulating circulating iron concentrations Overexpression of hepcidin results in severe iron deficiency and anemia whereas hepcidin deficiency leads to iron overload Not surprisingly abnormalities in hepcidin production and circulating concentrations are highly correlated with various disease states such as renal disease cancer ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Ultrasound Based Device to Guide Treatment of Graft Versus Host Disease Using Skin Elasticity as a Biomarker

    SBC: Microelastic Ultrasound Systems, Inc.            Topic: 102

    Ultrasound Based Device to Guide Treatment of Graft Versus Host Disease using Skin Elasticity as a Biomarker ABSTRACT Sclerotic chronic graft versus host disease cGVHD develops in of allogenic Human Stem Cell Transplant HCT recipients and is associated with significant morbidity and mortality GVHD is treated with immunosuppression which puts patients at severe risk of infection ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. A Novel Hernia Mesh to Improve Anchor Point Fixation and Prevent Hernia Formation

    SBC: Deep Blue Medical Advances, Inc.            Topic: 300

    Abstract Two million laparotomies are performed annually in the U S with ventral hernia being a frequent complication in of patients The average cost patient for each hernia operation in the U S in was $ which amounts to $ billion annually The ten year ventral hernia recurrence rate is There are $ B in hernia meshes sold annually in the United States With ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

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