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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Development and validation of therapy for mucopolysaccharidosis III
SBC: Phoenix Nest Inc. Topic: 103Project Summary Sanfilippo disease (mucopolysaccharidosis type III; MPS III) is a devastating neurodegenerative lysosomal storage disorder of childhood whose pathologic features are neurologic: slowing of development, severe behavioral problems, progressive cognitive decline, dementia, and decline in motor skills leading to immobility, unresponsiveness, and death. We have focused on MPS IIID cause ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
BioSphincter to Treat Fecal Incontinence. Phase 1/2 Clinical Trial. SBIR Phase IIB
SBC: CELLF-BIO LLC Topic: 300Project Summary/Abstract:Fecal incontinence (FI), the involuntary soiling of various amounts of liquid and solid stool, is often devastating from a social, psychological, and hygiene perspective. Men and women suffer from FI equally with a range of 2 - 6% in people aged 20 - 30 years. The prevalence increases to over 15% in people older than 70 years1. FI may result from an isolated or combined lo ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Validation of a salivary miRNA diagnostic test for autism spectrum disorder
SBC: Quadrant Biosciences Inc. Topic: 103Autism spectrum disorder (ASD) is a continuum of neurodevelopmental characteristics that includes deficits in communication and social interaction, as well as restrictive, repetitive interests and behaviors. ASD is an increasing public health concern, with about 1 in 45 American children diagnosed with ASD in 2014, a 10-fold increase in prevalence over the past 40 years. The effect of ASD on both ...
STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Administrative Supplement for the Evaluation of the novel, uni-directional, Pd-103 CivaSheet for Lung Cancer
SBC: CIVATECH ONCOLOGY INC Topic: NCIParent Award: R44CA217587 Clinical Evaluation of the novel, Uni-directional Pd-103 CivaSheet for Lung Cancers CivaTech Oncology’s mission is to provide improved radiation therapy directly to localized tumors. The Company has developed a novel, polymer-encapsulated, membrane-like radiation source that emits radiation on only one side of the device – CivaSheet®. This directional source is compa ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Living with CKD: An E-Learning Platform for Adolescents with CKD about the Disease and its Management
SBC: 3-C Institute for Social Development, Inc. Topic: 300Abstract Chronic kidney disease (CKD) is a progressive condition, characterized by an irreversible deterioration of renal function that gradually progresses to end-stage renal disease, requiring dialysis or kidney transplant. CKD and its co-morbidities (e.g., hypertension, anemia, acidosis, and metabolic bone disease) require strict treatment adherence to halt progression and improve outcomes. Unf ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Point-of-care device to identify patients at risk for preeclampsia
SBC: AFFINERGY, LLC Topic: NAlthough international trends for maternal mortality have shown an overall decline, maternal mortality rates in the United States have increased by andgt;25% since 2000. One of the leading causes for this increase is preeclampsia, a complication of pregnancy characterized by elevated blood pressure, proteinuria, and endothelial dysfunction involving multiple organ systems. Worldwide, preeclampsia ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
CometChip: Development of a high throughput DNA damage assay in hepatocytes
SBC: INTEGRATED LABORATORY SYSTEMS, LLC Topic: NIEHSAn estimated 10,000 animals are used in toxicology safety assessments to meet all regulatory requirements with testing spanning 5 to 10 yrs and exceeding $10 million dollars. There is a critical need to reduce reliance on animal testing and to develop highly predictive human-based biological models for safety assessments. Replacement of traditional animal toxicity tests for toxicology safety asses ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Increased sensitivity of minimal residual disease monitoring using peripheral blood in pediatric patients with acute lymphoblastic leukemia
SBC: BIOFLUIDICA, INC. Topic: 102Abstract Acute lymphoblastic leukemiaALLis the most common malignant disease in childhood and accounts for approximatelyof all cancers diagnosed before the age ofyearsThe primary cause of death for ALL patients is disease relapseThereforemonitoring for minimal residual diseaseMRDis considered the most powerful predictor of outcome in acute leukemiasincluding B type acute lymphoblastic leukemiaB AL ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
An Integrative Approach to Control Group Creation for Prevention Research
SBC: PREVENTION STRATEGIES, LLC Topic: 550PROJECT ABSTRACTThe goal of this Phase II SBIR project is to develop a method for creating algorithmically generated control groupsvirtual controlsThese will be composed of synthetic cases that have two characteristicspretest similarity to whatever prevention treatment group may present itself andpatterns of change over time that closely mimic the normal course of alcohol and drug use developmentT ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
A nucleosome sliding assay platform to screen inhibitors of SWI/SNF chromatin remodeling complexes
SBC: Epicypher, Inc. Topic: 400PROJECT SUMMARYNearlyof all cancers contain mutations in subunits from the SWI SNF family of NucleosomeNucremodeling complexesThe SWI SNF family regulates local genome access by pumping DNA around histone octamersthusslidingor remodeling Nucs within chromatinRecurrent somatic mutations in SWI SNF subunits are observed in multiple cancerssupporting a driver role in tumorigenesisThe mutated complexe ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health