Award Data

DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

N/A

THE OBJECTIVE OF THIS PROJECT IS TO DEVELOP A NEW CLASS OF BIOSENSORS BASED ON THE USE OF COLLOIDAL GOLD DIRECTLY OR DEPOSITED AS A POROUS GOLD FILM. THE KEY TO THE APPROACH ISTHE IMMOBILIZATION OF ENZYMES ON GOLD SURFACES THAT PROVIDE FOR HIGHFLUX, HETEROGENEOUS ELECTRON TRANSFER. THE FEASIBILITY OF CONSTRUCTING THIS NEW CLASS OF BIOSENSORS WILL BE EVALUATED BY THE END OF PHASE I. THE OBJECTIVES ...

78618S Robust and reliable trace-gas analyzers (e.g., for isotopic carbon, methane, nitroxide, ammonia, etc.), suitable for long-term measurements, are not commercially available. Such analyzers are needed to achieve a better understanding of the global budget of these trace gases and to quantify their exchanges between the atmosphere and the terrestrial biosphere. This project will develop a tu ...

78011S Many industrial liquid-phase catalytic processes that require the use of some kind of active species (e.g. sensors, biosensors, chelating agents, and chemical traps) cannot be ¿heterogeneized¿ without significantly penalizing chemical activity and/or selectivity. Biphasic liquid media strategies are an alternative, but these rely heavily on confinement of the active species in one of th ...

Manning Applied Technology proposes to develop a handheld infrared spectrometer, ideally suited to detection of airborne chemical agents at and below permissible exposure limits. This approach offers unmatched sensitivity and specificity for detection of all types of chemical vapors. The instrument is modular, rugged, compact and highly sensitive. Volume pricing will be less than $1000 each. ...

78845S The Department of Energy desires to increase fuel efficiency by reducing vehicle weight. Carbon fiber composites offer one promising way to do this, but difficulties in building economical, consistent, high quality preforms has limited the introduction of this material. This project will to adapt a well established pulp molding technology to produce carbon fiber preforms for lightweight ...

UP TO 35,000 WORKERS OF THE U.S. CHEMICAL INDUSTRY AND MORE THAN 270,000 WORKERS IN THE PETROLEUM AND COAL-RELATED INDUSTRIES MAY BE EXPOSED DAILY TO CARCINOGENIC AND MUTANOGENIC COMPOUNDS FROM THE AROMATIC AMINE GROUP. COAL GAS, INC. DEVELOPED A VERY SIMPLE HIGH-TECHNOLOGY APPROACH TO MONITORING THE EXPOSURE OF PERSONNEL TO TRACE LEVELS OF POLLUTANTS AND IS PROPOSING TO CONDUCT R & D WHICH WILL E ...

79454S Despite advances in modern electron optics, which have permitted observation with unprecedented resolutions, most materials science research involves the quantification of static properties of materials. This is mostly due to limitations in modern day equipment and the time and cost associated with modifying existing microscopes. Consequently a need exists to extend the current ability t ...

Effective collective protection fabrics must have a reliable closure system. During our Phase I Work Plan, Sigma-K began developing a Hermetic Textile Closure Hardware (HATCH) system. The HATCH combines both a magnetic and geometric self locking mechanism that will provide a hermetic seal when closed. Our current Phase I successes include developing self closing samples that can provide a hermetic ...