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The Award database is continually updated throughout the year. As a result, data for FY21 is not expected to be complete until September, 2022.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Adipose Derived Adult Stem Cells in Hepatic Regeneration

    SBC: VESTA THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Liver failure secondary to hepatitis, hepatotoxin exposure, and cirrhosis threatens the lives of thousands in the United States alone. Estimates of yearly direct healthcare costs for liver disease in the U.S. range from $60 billion to over $100 billion. Vesta Therapeutics has developed proprietary technologies for the isolation and preservation of primary hepat ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  2. A Novel Protection Device for Shock Wave Lithotripter

    SBC: Genognomon, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The shock wave lithotripsy (SWL) was first introduced successfully in clinical treatment in the earlier 1980s by Dornier Medical System in Germany. Now it has become the modality for urolithiasis diseases. However, SWL also causes acute renal injury, such as hemorrhage, hematoma, edema and enlargement of kidney. Although most patients recover well following ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  3. A Novel Protection Device for Shock Wave Lithotripter

    SBC: Genognomon, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The shock wave lithotripsy (SWL) was first introduced successfully in clinical treatment in the earlier 1980s by Dornier Medical System in Germany. Now it has become the modality for urolithiasis diseases. However, SWL also causes acute renal injury, such as hemorrhage, hematoma, edema and enlargement of kidney. Although most patients recover well following ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  4. Array-based Promoter Detection and Analysis

    SBC: O.D. 260, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The sequencing of genomes has generated a huge amount of data still to be annotated. Computational methods are available to detect putative transcriptional promoter regions, but they are not 100% efficient and must be confirmed by experimentation. Unfortunately the wet-bench procedures that are currently available to study promoters are time-consuming, laborio ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  5. A Worldwide Research Network of Dynamic Cardiac Images

    SBC: HEART IMAGING TECHNOLOGIES, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): This is a Phase I of a fast-track STTR application submitted in response to Program Announcement PA-03-001 ("Knowledge Integration across Distributed Heterogeneous Data Sources"). We propose a collaborative effort between Heart Imaging Technologies, LLC (HeartIT) and Duke University's Cardiovascular Magnetic Resonance Center (DCMRC). The goal of the collaborati ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  6. A Worldwide Research Network of Dynamic Cardiac Images

    SBC: HEART IMAGING TECHNOLOGIES, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): This is a Phase I of a fast-track STTR application submitted in response to Program Announcement PA-03-001 ("Knowledge Integration across Distributed Heterogeneous Data Sources"). We propose a collaborative effort between Heart Imaging Technologies, LLC (HeartIT) and Duke University's Cardiovascular Magnetic Resonance Center (DCMRC). The goal of the collaborati ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  7. Bioreactor for Engineered Bioartificial Tissues (BATS)

    SBC: Flexcell International Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): Few commercial bioreactors are available for the culture of three dimensional (3D) tissues. Flexcell's strategy is to provide a commercial bioreactor allowing ease of operation to produce molded 3D tissue constructs in cell- populated matrix gels of variable geometries with controlled nutrient perfusion and mechanical stimulation. This design is based on a vali ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  8. Bioreactor for Engineered Bioartificial Tissues (BATS)

    SBC: Flexcell International Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): Few commercial bioreactors are available for the culture of three dimensional (3D) tissues. Flexcell's strategy is to provide a commercial bioreactor allowing ease of operation to produce molded 3D tissue constructs in cell- populated matrix gels of variable geometries with controlled nutrient perfusion and mechanical stimulation. This design is based on a vali ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  9. Bone Regeneration Scaffolds

    SBC: Encelle, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): In 2001, a spinal fusion procedure was performed on average every 2 minutes in the United States at a mean cost of $34,000. Autograft bone from the iliac crest, the "gold standard" bone graft material for this procedure, results in non-union failures in 5% to 35% of procedures with morbidity and pain at the donor site in up to 25% of procedures after 2 years. R ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  10. Carbon Nanotube Field-Emission Micro-focus X-ray Tube

    SBC: XINTEK, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Substantial technological growth has spurred a new interest in imaging techniques, and their usage has grown considerably. High-resolution small animal imaging systems have emerged as important new tools for laboratory animal research. X-ray imaging is widely used in diagnostic radiology, biomedical research and a wide variety of industrial applications. We pro ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
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