Award Data

DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

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NanoCeramr filtration media has been developed for purification of water. The active component is a nano alumina fiber only 2 nanometers in diameter. When dispersed with microglass fibers as part of a non-woven fibrous filter it is capable of retaining sub-micron and nanosize particles smaller than virus while maintaining a high flux. Such media has a dirt holding capacity tens of times greater ...

THE OBJECTIVE OF THIS PROJECT IS TO DEVELOP A NEW CLASS OF BIOSENSORS BASED ON THE USE OF COLLOIDAL GOLD DIRECTLY OR DEPOSITED AS A POROUS GOLD FILM. THE KEY TO THE APPROACH ISTHE IMMOBILIZATION OF ENZYMES ON GOLD SURFACES THAT PROVIDE FOR HIGHFLUX, HETEROGENEOUS ELECTRON TRANSFER. THE FEASIBILITY OF CONSTRUCTING THIS NEW CLASS OF BIOSENSORS WILL BE EVALUATED BY THE END OF PHASE I. THE OBJECTIVES ...

78897S Plasma fusion research experiments require magnetic field measurements over a wide range of bandwidth and sensitivity. However, existing pickup coil sensors are limited in bandwidth, require time integration, and perturb the experiment when used as inserted diagnostics. Novel sensors that can be used for edge or insertion measurements of magnetic fields ranging from 0.01 to 100 G over a b ...

78846S Investment in the U.S. power grid infrastructure has not kept pace with increased energy demands, and consequently, existing power lines must operate close to conservative safety limits. The development of advanced instrumentation could simultaneously improve efficiency and maintain reliability. Next generation sensors must be low-cost to allow widespread deployment while providing critic ...

A FREE FALL WATER SAMPLER BASED ON THE CHOPSTICK WATER SAMPLER BAG WILL BE DEVELOPED. THIS PORCUPINE SAMPLER WILL BE CAPABLE OF TAKING UP TO 36 THREE LITER WATER SAMPLES AT DEPTHS CONTROLLED FROM THE SURFACE, OR AT DEPTHS DETERMINED BY AN INTERNAL CONTROLLER. THE SAMPLE WILL BE OPTIMIZED FORMINIMUM TRAVEL TIME FROM THE SURFACE TO THE BOTTOM AND BACK SO THAT THE CURRENT FOUR HOUR ON STATION TIME FO ...

THIS PROJECT IS TO DESIGN AND CONSTRUCT A MICROCOMPUTER-BASED INSTRUMENT FOR QUANTITATING SIZE DISTRIBUTIONS OF NUCLEIC ACIDS (DNA AND RNA) SEPARATED ACCORDING TO SIZE BY GEL ELECTROPHORESIS. THE STARTING POINT FOR ANALYSIS OF FLUORESCENCE-STAINED DNA IN GELS WILL BE THE IMAGE DIGITIZATION OF THE ENTIRE GEL ELECTROPHORETIC PATTERN (OR SPECIFIED PORTIONS OF IT) SO THAT THE RELATIVE INTENSITIES OF F ...

The pressing need exists within industry to accurately measure high aspect ratio microscale structures. For example, diesel injector nozzles are manufactured with microscale holes ranging from 50-200 micrometers in diameter and 3-5 mm depths. One fundamental challenge is to nondestrucvely measure these features in order to validate models, enhance manufacturing processes, and reduce fuel emissions ...

Manning Applied Technology proposes to develop a handheld infrared spectrometer, ideally suited to detection of airborne chemical agents at and below permissible exposure limits. This approach offers unmatched sensitivity and specificity for detection of all types of chemical vapors. The instrument is modular, rugged, compact and highly sensitive. Volume pricing will be less than $1000 each. ...