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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 1 - 10 of 6712 results
  1. AAV2-ASPA-Based Metabolic Intervention for Alzheimer's Disease

    SBC: ASKLEPIOS BIOPHARMACEUTICAL, INC.            Topic: NIA

    Abstract We propose to initiate preclinical development of a gene therapeutic targeted to Alzheimer's Disease. The World Health Organization's and Alzheimer's Disease International's report on Dementia (2012) recognizes that the global burden of AlzheimerDisease is forecast to worsen significantly with prevalence predicted to double every 20 years. Interventions that could prov ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Ab Alphavirus Replicon Vaccine against Cytomegalovirus

    SBC: GREER LABORATORIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The objectives of the proposed research are to develop further an alphavirus replicon particle vaccine against human cytomegalovirus (CMV). CMV causes a chronic, persistent infection and is an important cause of morbi

    SBIR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  3. A Biodegradable Thin-Film Mulching System for Weed Suppression in Commercial Crop Production

    SBC: Technical Designs Inc.            Topic: N/A

    Weeds reduce the productivity of vegetable crops. Noxious weeds like nutsedge can contaminate a field in one and a half years. To remediate the weed cost, $7,000 to $11,000 for plastic, fumigant and hand weeding is necessary in strawberries. In southern California, 10 to 20 percent of the farmland has a high-density infestation of nutsedge. Methyl bromide applied at high levels is partially effect ...

    SBIR Phase I 2009 Department of Agriculture
  4. A Biodegradable Vascular Coupling Device for End-to-End Anastomosis

    SBC: Microsurgical Innovations Inc            Topic: NHLBI

    Project Summary The objective of this Phase I SBIR proposal is to demonstrate the feasibility of a device designed to connect two small vessels together simply and easily and that would replace the hand suturing technique currently used to connect vessels in microsurgery and macrovascular end to end vascular repair surgeries This completely biodegradable vascular coupling device VCD being devel ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. A Biodegradable Vascular Coupling Device for End-to-End Anastomosis

    SBC: Microsurgical Innovations Inc            Topic: NHLBI

    Project Summary The objective of Microsurgical InnovationsMSIin this proposal is to develop a biodegradable vascular coupling deviceVCDwhich would replace the hand suturing technique currently used to connect arteries and veins in microvascular and macrovascular end to end vascular repair surgeriesOur device works for both arteries and veins and can rapidly connect the two vessel ends together in ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  6. A BIOLOGICAL MODEL OF THE EFFECTS OF TOXIC SUBSTANCES

    SBC: Topical Testing, Inc            Topic: N/A

    DUE TO THE BASIC NATURE OF MILITARY OPERATIONS, IT IS SOMETIMES NECESSARY FOR AIR FORCE PERSONNEL TO BE EXPOSED TO TOXIC CHEMICALS IN THEIR WORK ENVIRONMENT EITHER AS A PROTRACTED LOW-LEVEL EXPOSURE OR AS A HIGH-LEVEL, ACUTE EXPOSURE. THE APPLICATION HEREIN PROPOSES TO USE THE ANTERIOR EYE (CORNEA AND CONJUNCTIVA) AND ITS SENSORY INNERVATION AS AN ASSAY OF TOXIC EFFECTS. THE ANTERIOR EYE HAS UNIQU ...

    SBIR Phase II 1990 Department of DefenseAir Force
  7. A BIOLOGICAL MODEL OF THE EFFECTS OF TOXIC SUBSTANCES

    SBC: Topical Testing, Inc            Topic: N/A

    N/A

    SBIR Phase I 1989 Department of DefenseAir Force
  8. A biomarker of aging as a predictor of kidney transplant function

    SBC: HEALTHSPAN DIAGNOSTICS, LLC            Topic: NIA

    ABSTRACT The number of kidney transplant candidates on the waiting list continues to increase each year, while the number of kidney donations remains stagnant. The enduring donor shortage compels clinicians to use kidneys from marginal donors, referred toas expanded criteria donors (ECD). ECD kidneys, obtained primarily from older donors, have a higher risk of delayed graft function and graft loss ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. A Biosynthetic Degradable Textile for Soft Tissue Reconstruction

    SBC: Deep Blue Medical Advances, Inc.            Topic: 300

    AbstractBiosynthetic or synthetic degradable hernia mesh is the fastest growing segment of the hernia mesh marketreaching$M in sales inwith Bard controllingof the US marketfollowed by GoreNovus Scientificand EthiconWhile biosynthetic mesh may be used in any type of hernia repairit is most commonly used in ventral hernia repair cases where there is an increased risk of bacterial infectionThe reason ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. A Biosynthetic Degradable Textile for Soft Tissue Reconstruction

    SBC: Deep Blue Medical Advances, Inc.            Topic: 300

    ABSTRACT Laparotomy patients are plagued with ventral hernias occurring and recurring in up to 30% of cases. Hernia occurrence and recurrence is caused by anchor point failure of both permanent and degradable mesh (i.e. suture, tacks, and screws cheese-wire through mesh and tissue, resulting in mesh migration and/or contraction). Simply, hernias occur or recur where mesh is not adequately anchored ...

    SBIR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
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