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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Labeless, Reagentless, Biosensor

    SBC: AGAVE BIOSYSTEMS INC.            Topic: N/A

    The preponderance of biosensors under development today rely on labeling reagents such as fluorescent, radioisotopic or enzymatic tags. As a result, the added complexity of these reagents and their incorporation into the detection system has resulted in designs that are difficult to implement or that require significant sample preparation steps before introduction into the detection instrument. ...

    SBIR Phase I 1998 Department of DefenseOffice for Chemical and Biological Defense
  2. Minature Biological Detector Using On-Chip Eletrostatic Spray Separation

    SBC: American Research Corporation of Virginia            Topic: N/A

    Recent developments in the world political arena have led to The need for miniaturized instrumentation for rapid characterization of micro-organisms and toxins to protect military and civilian personnel against biological weapons and to allow timely administration of prophylactics. Considerable effort is currently underway to develop polymerase chain reaction (PCR) assays with automated samp ...

    SBIR Phase I 1998 Department of DefenseOffice for Chemical and Biological Defense
  3. Novel Microcantilever Biosensor for the Measurement of Biomolecular Forces

    SBC: LUNA INNOVATIONS INCORPORATED            Topic: N/A

    The ability to detect minute quantities of toxic biological substance s will provide the ability to quickly assess a situation so that an a ppropriate response to exposure can be orchestrated. Not only will t he development of this technology be important in toxic agent warfare detection, the biological sensors would be pertinent in commercial ap plications such as process control and point-of-ca ...

    SBIR Phase I 1998 Department of DefenseOffice for Chemical and Biological Defense
  4. RNA Detector-Molecule Methodology for Microorganism Biodetectors

    SBC: Invitro Diagnostics, Inc.            Topic: N/A

    Current geopolitical strategies require effective warfare countermeasures to protect U.S. forces against biological and chemical threats. Today's molecular biology and immunological detection technologies cannot be used to produce automated biodetectors useable in the battlefield. New, improved detection technologies are needed to minimize the impact of chemical and biological weapons on Army per ...

    SBIR Phase I 1998 Department of DefenseOffice for Chemical and Biological Defense
  5. An automated, high throughput, resin-free device for large scale protein purification

    SBC: CFD RESEARCH CORPORATION            Topic: CBD12102

    Protein manufacturing is of paramount importance to chemical and biological defense applications. High-throughput protein purification is a critical need for rapidly scaling the target protein product. Existing purification methods primarly rely on synthetic-resin based chromatography, which is time-consuming, labor-intensive, expensive, and consequently, ill-suited for developing rapid countermea ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
  6. Affinity Matrix System for Large-Scale Protein Purification

    SBC: LUNA INNOVATIONS INCORPORATED            Topic: CBD12102

    Though vast improvements have been made in various protein expression platforms, limitations arise in the implementation of current purification methods. Traditional chromatographic methods are time intensive, carry heavy material costs, and are difficult to scale - reducing the benefits achieved in protein expression. Affinity-binding methods are promising for scale-up and swiftness of purificati ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
  7. A Novel, Aerodynamics-augmented Continuous Ionization System for Electrostatic Collection of Bioaerosols

    SBC: CFD RESEARCH CORPORATION            Topic: CBD12107

    Safe and efficient air ionization and filtration technology compatible to biodefense applications is of paramount importance. Current ionization methods are energy-intensive, costly, prone to ozone generation, or inefficient, and consequently ill-suited for building protection applications. To overcome these issues, we propose to develop and demonstrate a novel bioaerosol ionization and collection ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
  8. Microhydrogel Depot for Sustained Delivery of Prophylactic Bioscavenger

    SBC: LUNA INNOVATIONS INCORPORATED            Topic: CBD13107

    Neurotoxic organophosphorus (OP) agents (e.g. sarin, soman, VX and tabun) were developed initially as pesticides and adapted for chemical warfare. OP agents are fast acting and lethal at even very low doses. Countering the threat of intoxication by OP nerve agents is an important mission for homeland security. Currently, the most promising strategy to counter OP intoxication is to scavenge the age ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
  9. Narrowband Perfect Absorber using Metamaterials

    SBC: PHOEBUS OPTOELECTRONICS LLC            Topic: CBD11102

    We will continue developing a plasmonic metamaterial with strong absorption within a narrow band that is dynamically tunable over the 8-10 micron range. A metamaterial consisting of one or more bi-layers of thin metal and dielectric films will trap, concentrate and absorb a narrow frequency band while strongly reflecting out-of-band light. Tuning the frequency of the absorption band may be achiev ...

    SBIR Phase II 2013 Department of DefenseOffice for Chemical and Biological Defense
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