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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

Displaying 1 - 10 of 5541 results
  1. Development of an Open Speech Signal Processing Platform

    SBC: Flat Earth Inc            Topic: NIDCD

    This proposal will create an open speech signal processing platformThe open computational framework will be used for developing algorithms that will help accelerate acoustic and hearing science researchIt will permit researchers to more rapidly and easily test new algorithms with greater controlperformanceand easeSeveral example systems will be created to show that the platform can be adapted to a ...

    SBIR Phase II 2017 Department of Health and Human Services
  2. NNCI Synapse: Development of a Mobile Application to Disseminate Neuroscience Training to Medical Professionals

    SBC: C4 Innovations, LLC            Topic: 102

    PROJECT SUMMARYABSTRACTWhile biological models of mental illness once emphasizedchemical imbalancesmodern perspectives increasingly incorporate a more nuanced understanding of genetics and epigeneticsneurotransmitters and neuroplasticityand the functional dynamics of neural circuitsYet despite extraordinary advances in neuroscience that have dramatically enhanced our understanding of the brain and ...

    SBIR Phase II 2018 Department of Health and Human Services
  3. Supportive Clinical Trial Tasks for Nanotechnology-Based Treatment of Oral Cancer

    SBC: PRIVO TECHNOLOGIES, LLC            Topic: NCI

    Preceding AwardNCI AwardRCAProject SummaryAccording to the Oral Cancer Foundationaboutpeople in the US will be newly diagnosed with oral cancerOCincausingdeathsOC is a severely neglected orphan disease with a lack of significant treatment advances indecadesHistoricallyOC has been present in heavy smokers and drinkersHowevermore recently OC has also become more prevalent in younger people due to an ...

    SBIR Phase II 2018 Department of Health and Human Services
  4. Motor Unit Drive (MU Drive) for Prosthetic Control

    SBC: ALTEC Inc            Topic: NICHD

    The proposed Phase II SBIR project will develop a unique motor unitMUbased control systemMU Drivethat uses neural firings measured noninvasively and in real time to drive an upper limb prosthesisOur Phase I effort successfully proved the technical merit and feasibility by demonstrating that MU firings can be measured from surface myoelectric recordings in real time and used to provide a proportion ...

    SBIR Phase II 2018 Department of Health and Human Services
  5. Immuno-Oncology for Pancreatic Cancer: A Combination Clinical Trial with Chemotherapy and Radiation

    SBC: ADVANTAGENE, INC            Topic: 102

    DESCRIPTIONprovided by applicantPancreatic adenocarcinoma has a dismalyear survival of andltThe only potential curative treatment is resectionbut this is achieved in andltof patients and most still die due to micrometastases or residual diseasePatients with unresectable disease receive palliative chemotherapy with a median survival of less thanmonthsThis application proposes a multi pronged approa ...

    SBIR Phase II 2018 Department of Health and Human Services


    Project SummaryAortic stenosisASis a common and lethal cardiac valve disease with an average survival time of onlyyears after diagnosis if no treatment is obtainedThe standard of care for moderate to severe cases of symptomatic AS is surgical valve repair or replacementwhich can necessitate open heart surgeryThisgold standardof care is plagued by substantial limitationsincluding high morbidity and ...

    SBIR Phase II 2018 Department of Health and Human Services
  7. Risk-based Patient Monitoring for Pediatric Cardiac Patients

    SBC: Etiometry Inc.            Topic: NHLBI

    AbstractDuring a successful PhaseeffortEtiometry collaborated with multiple world class pediatric centers to developvalidateand deploy novel analytics that combine multiple physiologic data streams into a probabilistic assessment of inadequate oxygen delivery to critically ill patientsThe analytics were integrated into the Etiometry Platform with the goal of improving physician situational awarene ...

    SBIR Phase II 2018 Department of Health and Human Services
  8. NeuroMAP System for Clinical Research

    SBC: ALTEC Inc            Topic: NINDS

    Motoneurons are the final neural circuits that link the brain with skeletal muscles to enable the body to moveImpairments in the ability to regulate movement currently affect overmillion Americans suffering from various neurological or musculoskeletal conditionsYet the deficits in motoneuron control that underlie many of these conditions are difficult to discern because current research tools used ...

    SBIR Phase II 2018 Department of Health and Human Services
  9. Preclinical development of teixobactin, a new antibiotic


    The long term goal of this program is to develop our novel antimicrobialteixobactininto a therapeutic for treating a wide range of infections caused by Gram positive pathogens including Staphylococcus aureusStreptococcus pneumoniaeBacillus anthracisMycobacterium tuberculosisEnterococcus faecalis and EfaeciumThe goal of this Phase IIB project is to complete preclinical development of teixobactin in ...

    SBIR Phase II 2018 Department of Health and Human Services
  10. PAR2 Pepducins as a Novel Treatment of Idiopathic Pulmonary Fibrosis


    Idiopathic pulmonary fibrosisIPFthe most common of the interstitial lung diseasesoccurs in aboutpeoplewithnew cases diagnosed annually in the USThe typical clinical course is a progressive fibrotic disease characterized by scarring and `honeycombingandaposof the lungs causing an irreversible loss of the tissueandapos s ability to transport oxygenCo morbid pulmonary hypertension is commonly seen in ...

    STTR Phase I 2018 Department of Health and Human Services

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