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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Novel non-invasive antigen detection assay for the diagnosis of active visceral leishmaniasis and to monitor the therapy efficacy of this disease

    SBC: DETECTOGEN INC.            Topic: NIAID

    ABSTRACTThe overall goal of this Phase II project is to validate novel leishmanial protein biomarkers for development of a non invasive urine based assay to diagnose active visceral leishmaniasisVLand to monitor the therapeutic efficacy of this serious diseaseVL is endemic incountriesaffectspeople a year and kills more thanof them children under ageVLalso known as kala azaris caused by parasites o ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  2. OnTrack> An Online Role-Playing Game

    SBC: C4 Innovations, LLC            Topic: 104

    Project Summary First episode psychosis is a serious mental health condition that affects youth and young adultsoften between the ages ofandThe illness is marked by hallucinationsdelusionswithdrawalpoor organization skillsand diminished cognitive and social functioningRecent research has demonstrated that programs designed to treat people experiencing early psychosis can reduce hospitalizationdecr ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Validation of an In Vitro Human Airway Model for Regulatory Toxicity Testing

    SBC: Mattek Corporation            Topic: NIEHS

    Results of Phase II research indicate that formal validation of the EpiAirwayin vitro human bronchial tissue model for predicting toxicity of inhaled chemicals is an attainable goalThe proposed Phase IIB cooperative agreement project is intended to realize this goal by conducting formal ring trial validation studies that will be submitted to regulatory agencies and the Organization for Economic Co ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  4. PANDAA for rapid genotyping of HIV-1 infected patients failing protease inhibitor ART in resource-limited settings

    SBC: ALDATU BIOSCIENCES, INC.            Topic: R

    TheWHO guidelines recommend anti retroviral therapyARTfor all HIV infected peopleand massive efforts to expand ART access will result in andgtM adults and andgtM children on ART byat a cost of almost US$BConsequentlythe number of patients prescribed alternativeprotease inhibitorPIbased ART following failure of first line regimens will also increaseStudies of patients on PI based ART in resource li ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Dermal Medical Countermeasures for Chemical Weapons Exposure

    SBC: Nano Terra, Inc.            Topic: CBD161003

    Chemical warfare agents (CWAs), such as nerve agents and mustard agents, pose serious threats to our warfighters and civilians. Current formulations of dermal medical countermeasures to CWAs can be absorbed through the skin causing systemic toxicities to the patients. These formulations are limited by the FDA for use only in small area of intact skin, which severely restricts the usefulness of the ...

    SBIR Phase I 2017 Department of DefenseOffice for Chemical and Biological Defense
  6. A novel immunotolerizing therapy for autoimmune vitiligo

    SBC: RADIKAL THERAPEUTICS, INC.            Topic: NIAMS

    Radikal TherapeuticsRTXis developing a pioneering therapy to restore immunotolerance and arrest progressive depigmentation in vitiligoAt our partnering institutionLoyola University Chicagoa variant to inducible Heat Shock Proteinwas developed with remarkable potential for the prevention and treatment of autoimmune vitiligoCarrying only a single amino acid modification to the proteinthis variant HS ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  7. An Intraoperative Guidance Platform for Radio Frequency Ablation

    SBC: NE Scientific, LLC            Topic: 102

    Project SummaryThe objective of this proposed research program is to develop a platform for planning and guidance during Radio Frequency AblationRFARFA is a thermally mediated ablation techniquewhere an applicator carrying one electrode is inserted into tumors percutaneouslyor via laparoscopyor open surgical approachesRadio FrequencyRFenergy is applieddenaturating and coagulating tissues in a volu ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Commercializing Praedicare Dx TM platform for guiding cancer treatments

    SBC: Eutropics Pharmaceuticals, Inc.            Topic: 102

    Abstract The Eutropics PraediCare Dxis an emerging clinical diagnostic assay that will be used to predict patient response to specific chemotherapiesUnlike existing assaysPraediCare Dxpredicts response to specific chemotherapies by direct evaluation of cancer cells potential to enter into an apoptotic state following exposure to therapyPraediCare Dxhas the potential to provide actionable data for ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Enabling point-of-care molecular diagnostics by developing an adaptive PCR instrument and on-demand kit reagents

    SBC: BIOVENTURES, INC            Topic: 172

    Because of its high sensitivitypolymerase chain reactionPCRis the gold standard for the diagnosis of many infectious diseasesbut generally only implemented in well equipped laboratoriesOne of the major roadblocks for expanding PCR to point of care markets is the lack of simplerobustsingle tube PCR designs which preserve its laboratory based high sensitivity and specificityIn this Fast Track STTR a ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  10. A Hand-Held Robot to Cure BPH

    SBC: Virtuoso Surgical, Inc.            Topic: NIBIB

    Project Summary AbstractThe objective of this proposal is to transform a hand held surgical robotic system for transurethral laser prostate surgery from a lab prototype into a commercial productThe system will feature needle sized arms deployed through the endoscope port and will enable independent tissue manipulationlaser aimingand visualizationmaking surgery more accurate and ef cientClinical si ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
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