List

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Bactericidal antibiotic for Vancomycin Resistant Enterococci

    SBC: Arietis Corporation            Topic: NIAID

    DESCRIPTIONprovided by applicantThe goal of the project is to develop a therapeutic against vancomycin resistant enterococcusVREThese infections are a serious health concern because antibiotic resistance has gotten to the point where there are few or no effective treatment options availableFor the enterococciresistance is inherently linked to toleranceth ability of the pathogen to survive in the p ...

    SBIR Phase II 2016 Department of Health and Human Services
  2. Low Cost and Rapid DNA-Based Biometric Device

    SBC: NetBio, Inc.            Topic: HSB091001

    Sensitive site exploitation activities are focused on collecting forensic evidence left behind by persons involved in terrorist or other illegal activity, and the biological evidence recovered is often referred to as"touch DNA samples". Touch samples include fingerprints, skin cells found on clothing (e.g. a shirt collar), and oral epithelial cells found on the opening of a soda can or the rim of ...

    SBIR Phase II 2011 Department of DefenseSpecial Operations Command
  3. Development of BA for treatment of cerebral cavernous malformation

    SBC: BIOAXONE BIOSCIENCES, INC.            Topic: 105

    DESCRIPTION provided by applicant Cerebral cavernous malformations CCMs also known as andapos cavernous angiomaandapos or andapos cavernomaandapos are common vascular abnormalities found in of the population exposing patients to a lifetime risk of hemorrhagic stroke seizures and other neurologic sequelae Approximately of CCM lesions present with clinically overt hemorr ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Microfabricated Implantable Flowmeter for CSF Shunts Phase II

    SBC: Infoscitex Corporation            Topic: NINDS

    DESCRIPTION (provided by applicant): An implantable wireless flow sensor system has been under development that would enable measurement of the flow of cerebrospinal fluid (CSF) through the ventriculoperitoneal (VP) shunt, currently used to treat hydrocephalus patients. CSF flow is a key indicator of shunt function, and there is currently no way to measure it in situ, resulting in the absence ...

    SBIR Phase II 2011 Department of Health and Human Services
  5. Type III Secretion Inhibitors for Anti-Infective Therapy

    SBC: MICROBIOTIX, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Pseudomonas aeruginosa infection is the leading cause of hospital-acquired pneumonia in patients undergoing mechanical ventilation. Current antibiotic treatments exhibit failure rates as high as 18%, even when the organism is susceptible to the antibiotic being administered. The goal of this project is to address this critical medical need by identifying specif ...

    SBIR Phase II 2011 Department of Health and Human Services
  6. STAT Palm-Sized Blood Counter

    SBC: CHAN RESEARCH, LLC            Topic: NHLBI

    DESCRIPTIONprovided by applicantThe overarching objective of this proposal is to attain data for FDAksubmission of a handheld miniaturized STAT Blood Counter usingL blood to yield a complete blood countCBCwithpart differentialThis dramatically decreased size and sample volume creates new opportunities in delivery of these hematology testsultimately leading to more streamlinedavailableand on demand ...

    SBIR Phase II 2016 Department of Health and Human Services
  7. IGF OT IGF SBIR TOPIC FAST TRACK BASE PHASE I LINE ITEM CERCLAGE FOR TREATING SECONDARY MITRAL REGURGITATION

    SBC: TRANSMURAL SYSTEMS LLC            Topic: NHLBI

    Development of Transcatheter Cerclage Mitral Valve Annuloplasty Cerclage

    SBIR Phase II 2016 Department of Health and Human Services
  8. IGF OT IGF TRANSCATHETER CAVOPULMONARY BYPASS ENDOGRAFT SBIR TOPIC DIRECT TO PHASE II IGF OT IGF

    SBC: TRANSMURAL SYSTEMS LLC            Topic: NHLBI

    Extra anatomic bypass or vascular shunts divert blood flow In congenital heart disease these surgical procedures are critical for management Children born with one functional ventricle or cardiac pumping chamber require two to three major cardiac surgery procedures for palliation The management goal is to divert systemic venous return deoxygenated blood from the heart directly to pulmonary a ...

    SBIR Phase II 2016 Department of Health and Human Services
  9. Novel Diagnostic Sequencing System for HIV Resistance Testing

    SBC: INTELLIGENT BIO-SYSTEMS, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): As of 2008 the CDC estimated that there were approximately 1.1 million persons in the U.S. infected with HIV- 1 and about 56,000 new cases are diagnosed each year. During the mid-to-late 1990s, advances in treatment slowed the progression of HIV to AIDS and related deaths. Unfortunately, the treatment often leads to the emergence of drug resistant mutants of HI ...

    SBIR Phase II 2011 Department of Health and Human Services
  10. Rapid sensitive low-cost test for resistant microbes causing hospital infections

    SBC: FIRST LIGHT BIOSCIENCES, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): We propose to develop a novel automated platform to enable rapid, sensitive, user-friendly, and cost-effective screening for the antibiotic resistant bacteria that frequently cause serious healthcare associated infections. Every year, about 100,000 deaths result from 2 million serious healthcare associated infections at an estimated cost of 35B. About 20,000 f ...

    SBIR Phase II 2011 Department of Health and Human Services

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government