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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. NNCI Synapse: Development of a Mobile Application to Disseminate Neuroscience Training to Medical Professionals

    SBC: C4 Innovations, LLC            Topic: 102

    PROJECT SUMMARYABSTRACTWhile biological models of mental illness once emphasizedchemical imbalancesmodern perspectives increasingly incorporate a more nuanced understanding of genetics and epigeneticsneurotransmitters and neuroplasticityand the functional dynamics of neural circuitsYet despite extraordinary advances in neuroscience that have dramatically enhanced our understanding of the brain and ...

    SBIR Phase II 2018 Department of Health and Human Services
  2. Supportive Clinical Trial Tasks for Nanotechnology-Based Treatment of Oral Cancer

    SBC: PRIVO TECHNOLOGIES, LLC            Topic: NCI

    Preceding AwardNCI AwardRCAProject SummaryAccording to the Oral Cancer Foundationaboutpeople in the US will be newly diagnosed with oral cancerOCincausingdeathsOC is a severely neglected orphan disease with a lack of significant treatment advances indecadesHistoricallyOC has been present in heavy smokers and drinkersHowevermore recently OC has also become more prevalent in younger people due to an ...

    SBIR Phase II 2018 Department of Health and Human Services
  3. Motor Unit Drive (MU Drive) for Prosthetic Control

    SBC: ALTEC Inc            Topic: NICHD

    The proposed Phase II SBIR project will develop a unique motor unitMUbased control systemMU Drivethat uses neural firings measured noninvasively and in real time to drive an upper limb prosthesisOur Phase I effort successfully proved the technical merit and feasibility by demonstrating that MU firings can be measured from surface myoelectric recordings in real time and used to provide a proportion ...

    SBIR Phase II 2018 Department of Health and Human Services
  4. Immuno-Oncology for Pancreatic Cancer: A Combination Clinical Trial with Chemotherapy and Radiation

    SBC: ADVANTAGENE, INC            Topic: 102

    DESCRIPTIONprovided by applicantPancreatic adenocarcinoma has a dismalyear survival of andltThe only potential curative treatment is resectionbut this is achieved in andltof patients and most still die due to micrometastases or residual diseasePatients with unresectable disease receive palliative chemotherapy with a median survival of less thanmonthsThis application proposes a multi pronged approa ...

    SBIR Phase II 2018 Department of Health and Human Services
  5. CLOSURE DEVICE FOR TRANSCAVAL ACCESS TO THE ABDOMINAL AORTA

    SBC: TRANSMURAL SYSTEMS LLC            Topic: NHLBI

    Project SummaryAortic stenosisASis a common and lethal cardiac valve disease with an average survival time of onlyyears after diagnosis if no treatment is obtainedThe standard of care for moderate to severe cases of symptomatic AS is surgical valve repair or replacementwhich can necessitate open heart surgeryThisgold standardof care is plagued by substantial limitationsincluding high morbidity and ...

    SBIR Phase II 2018 Department of Health and Human Services
  6. Novel Methodology for Identification of Senolytics that Reduce Age-related Disease and Dysfunction

    SBC: Recursion Pharmaceuticals, LLC            Topic: NIA

    DESCRIPTIONprovided by applicantChronic diseases of aging account for a significant proportion of healthcare spending and result in a painful and limiting existence for many tens of millions of Americans and hundreds of millions of people around the worldRecursion Pharmaceuticals has developed a drug discovery platform that re purposes known drugs for the treatment of such diseasesThe platform con ...

    SBIR Phase II 2018 Department of Health and Human Services
  7. Automated peak fitting and analysis software for advanced gas chromatography and mass spectrometer systems

    SBC: Aerodyne Research, Inc.            Topic: 827

    TECHNICAL ABSTRACT: Recent advances in gas chromatographic (GC) and mass spectrometric (MS) techniques for atmospheric measurements have led to highly complex data sets that have overwhelmed the capabilities of current data analysis software. We propose a new method for the automated reduction of chromatographic data using peak-fitting algorithms. By relying upon constrained peak-fit parameterizat ...

    SBIR Phase II 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  8. Development of a Portable 3-dimensional Variational (3DVAR) Data Assimilation Module for NOAA Operational Forecasting Systems

    SBC: REMOTE SENSING SOLUTIONS, INC.            Topic: 814

    TECHNICAL ABSTRACT: We propose to continue the development of a generalized 3DVAR data assimilation module, in an open-source and non-proprietary programming language, which is compatible with FVCOM and incorporated into the Lake Erie Operational Forecast System (LEOFS). We will leverage our experience and expertise in using 3DVAR for a ROMS-based real-time forecast system for the California coast ...

    SBIR Phase II 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  9. Automated HCl laser monitor for long term and flight deployments

    SBC: Aerodyne Research, Inc.            Topic: 813

    TECHNICAL ABSTRACT: Tropospheric oxidation capacity is dominated by HOx photochemistry, however halogen atoms and oxides significantly affect these chemical cycles. A sensitive and robust measurement of gaseous HCl is critically important to improve our understanding of halogen chemistry and its impacts on the spatial and temporal oxidation capacity of the atmosphere. In Phase I, we met all of our ...

    SBIR Phase II 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  10. Risk-based Patient Monitoring for Pediatric Cardiac Patients

    SBC: Etiometry Inc.            Topic: NHLBI

    AbstractDuring a successful PhaseeffortEtiometry collaborated with multiple world class pediatric centers to developvalidateand deploy novel analytics that combine multiple physiologic data streams into a probabilistic assessment of inadequate oxygen delivery to critically ill patientsThe analytics were integrated into the Etiometry Platform with the goal of improving physician situational awarene ...

    SBIR Phase II 2018 Department of Health and Human Services

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