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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Protease resistant D peptide Inhibitors of Ebola Virus Entry

    SBC: NAVIGEN, INC.            Topic: R

    DESCRIPTION provided by applicant Ebola virus causes highly lethal hemorrhagic fever in humans and non human primates Since the first outbreak in there have been over natural human outbreaks with an average mortality rate near There are no approved agents to prevent or treat Ebola infection Due to ease of dissemination high lethality and ability to cause widespread panic the ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Image-Guided Transurethral HIFU for Genitourinary Therapy

    SBC: ACOUSTIC MEDSYSTEMS, INC.            Topic: 400

    DESCRIPTION provided by applicant Stress urinary incontinence SUI in women is an increase of pelvic floor compliance which results in decrease of urethral pressure typically through childbirth and presents as urine leakage during exertion SUI has significant impact on womenandapos s health including an association with increased levels of depression Curative options are limited to the in ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Developing A Novel Therapy for Diabetic Retinopathy

    SBC: Charlesson, LLC            Topic: W

    DESCRIPTION provided by applicant Diabetic retinopathy DR is a common complication of diabetes and a leading cause of vision loss in the United States Although the anti vascular endothelial growth factor VEGF drugs have shown impressive efficacies on wet age related macular degeneration AMD they are only effective in approximately of patients with DR likely due to the multi factori ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Lateral Flow Assay for Diagnosis of Histoplasmosis

    SBC: Immuno-mycologics, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Progressive disseminated histoplasmosis is a common and serious opportunistic infection among individuals with HIV AIDS In many resource limited areas such as Latin America incidence rates in HIV AIDS can be andgt with mortality rates among cases andgt Successful treatment of histoplasmosis in patients with AIDS requires early diagnosis and treatme ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  5. A Force-controlled Probe Based Platform for Single-Cell Biomolecular Delivery

    SBC: INFINITESIMAL, LLC            Topic: 100

    DESCRIPTION provided by applicant This proposed Phase II project will lead to a commercial product capable of transfecting individual target cells This new biotool uses a patented microfabricated chip called a nanofountain probe NFP to deliver molecules into live individual target cells by single cell electroporation which induces temporary nanopores in the cell membrane via the applicat ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  6. Small blood pumps for small patients

    SBC: Vadovations, Inc.            Topic: NHLBI

    DESCRIPTION provided by applicant Heart failure and congenital heart defects threaten the lives of several thousand children each year The only FDA approved long term pediatric heart support device is the Berlin Heart Excor which is based on year old technology and is fraught with complications including blood clots forming in the device requiring frequent device replacement The recipien ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Expansion of an efficient drug repurposing platform for rare genetic diseases.

    SBC: Recursion Pharmaceuticals, LLC            Topic: 300

    DESCRIPTION provided by applicant There are thousands of rare genetic diseases that have no approved treatment Recursion Pharmaceuticals has developed a drug discovery platform that seeks to re purpose known drugs for the treatment of such diseases The platform consists of high content immunofluorescent image analysis and transcellular resistance measurements These measurements evaluated usi ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Quantitative Optical Assessment of Middle Ear Disease

    SBC: PHOTONICARE INC            Topic: NIDCD

    DESCRIPTION provided by applicant PhotoniCare Inc is a medical device company developing a handheld biophotonics imaging system suitable for use by otolaryngologists ear nose and throat specialists ENT and primary care physicians PCP to enable real time D assessment of sub surface tissue structure in the middle ear Significance ENTs and PCPs have limited tools with which to diagn ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  9. A Tissue Implantable Microbiosensor

    SBC: Pinnacle Technology, Inc.            Topic: 101

    DESCRIPTION provided by applicant Abstract In this Phase II SBIR we will commercialize tissue implantable microbiosensors to measure glucose lactate and oxygen for use in freely moving animals We will also develop and commercialize a sensor array composed of a glucose biosensor a lactate biosensor and an oxygen sensor Biosensors provide high temporal resolution and low analyte consumpti ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  10. A turn-key optogenetics and electrophysiology measurement system

    SBC: Pinnacle Technology, Inc.            Topic: NIA

    DESCRIPTION provided by applicant The goal of this project is to design and commercialize tethered and wireless turn key optogenetics and electrophysiological neurotransmitter behavior measurement systems for use in mice and rats Optogenetics harnesses a combination of genetic and optical methods to directly control neuronal events in specific cells of the central nervous system These methods ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
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