Award Data

Sepsis is a poorly understood clinical syndrome and is characterized by a dysregulation of the immune system?s response to infection. It is the leading cause of death and is the most expensive condition treated in U.S. hospitals, exerting a $20.3 billion burden annually, 5.2% of total costs to the healthcare system nationwide. Sepsis is highly time critical and every 1-hour delay in antibiotics is ...

The broader impact/commercial potential of this project is to enable mobile robots to coexist harmoniously with people in their homes and offices. The market for consumer and office robots is projected to grow 17% annually, seven times faster than the market for manufacturing robots, reaching $1.5B by 2019. An important step toward market growth is creating autonomous robots that are unobtrusive, ...

This SBIR Phase II project will benefit society by reducing the cost of manufacturing biologic pharmaceuticals and improving their quality, including pharmaceuticals that are currently too costly to manufacture because they target relatively small patient populations. In order to accelerate the availability of newly discovered drugs, the pharmaceutical industry and federal regulatory agencies have ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project will result in a significant improvement in the performance, power, and cost of deploying machine learning (ML) solutions through horizontal platform technologies that enable many vertical applications. This improvement will accelerate deployment of intelligent systems and improve scalability ...

This Small Business Innovation Research Phase II project targets the fabrication of devices capable of focusing X-rays with high energy (from 10 keV to above 100 keV) to spot sizes as small as 7 nanometers. This capability is critical for imaging, microtomography, and elemental and structural analyses of materials and will permit imaging in spectral ranges and at resolutions unavailable today. The ...

This SBIR Phase II project, the Engineering Design Instruction Software for implementing Objectives of Next generation standards (EDISON), will combine Science Technology Engineering and Mathematics (STEM) concepts together with engineering design, simulation, Augmented Reality (AR), 3-D printing, and real-world experiments. The project will create a collaborative platform for middle school engine ...

This SBIR Phase II project will expand on Phase I R&D work to build, test, and optimize a web-based software system for the classroom setting to complement the digital library app for home use developed in Phase I. This cost-effective system will further promote adult-mediated dialogic reading routines with children 0-7 years in age. Early exposure to dialogic reading has been shown to foster virt ...

The broader impact/commercial potential of this project is its capability to create a positive impact on current and future wireless systems. Multifunctional reconfigurable antenna (MRA) technology targeted in this project enables a single antenna element to dynamically change its frequency band, radiation pattern and polarization properties, which directly impact the radio-frequency (RF) coverage ...

This SBIR Phase I project addresses the need to reduce the time associated with conducting tests currently used to establish targeted antibiotic (and dose) to treat infections. Sepsis and septic shock are one of the leading contributors to death in US Hospitals, responsible for 250,000 deaths annually (estimated at 30-50% of all hospital deaths). To combat these high death rates, time is of the es ...

This Small Business Innovation Research (SBIR) Phase II project will develop a ceramic hydrogen fuel appliance (CHFA) using ceramic microreactor modules (CMMs) using a low-cost, net-shape manufacturing process, and a new material, that was developed in the Phase I project. The new material developed was demonstrated to have excellent capability for cost-effective microfabri ...