Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. BLOOD MICRO-CULTURE ASSAY OF HORMONE-DEPENDENT PROLIFERATION IN HEMATOLOGIC DISORDERS

    SBC: Chi Associates, Inc.            Topic: N/A

    IN THE PAST 20 YEARS, THE PROGRESSIVE ABILITY TO GROW BLOOD FORMING CELLS IN TISSUE CULTURE, HAS DRAMATICALLY INCREASED OUR UNDERSTANDING OF BLOOD DISORDERS AND HAS ALLOWED THE ISOLATION OF MANY NEW HEMOPOIETIC HORMONES WHICH MAY NOW BE USED FOR SOME OF THESE DISORDERS. NEVERTHELESS, UNTIL RECENTLY, THE HEMOPOIETIC CULTURE ASSAYS HAVE BEEN TIME CONSUMING, EXPENSIVE AND LABOR INTENSIVE, AND THE HOR ...

    SBIR Phase II 1989 Department of Health and Human Services
  2. INVERSION OF LAPLACE TRANSFORMS ON MICROCOMPUTERS

    SBC: Micromath Inc.            Topic: N/A

    THE APPLICATION OF PHYSICAL-CHEMICAL PRINCIPLES TO BIOLOGICAL SYSTEMS FREQUENTLY LEADS TO SITUATIONS IN WHICH THE QUANTITATIVE TREATMENT OF CONCEPTUALLY SIMPLE MODELS IS CONFOUNDED BY THE COMPLEXITY OF THE SYSTEM. SUCH IS THE CASE, FOR EXAMPLE, IN THE STUDY OF THE PERMEATION (AND POSSIBLE CONCURRENT METABOLISM) OF DRUGS THROUGH COMPLEX BIOLOGICAL MEMBRANES, THE PHYSIOLOGICAL MODELING OF THE DISTRI ...

    SBIR Phase II 1989 Department of Health and Human Services
  3. RADIOLABELED ANTIBODY DELIVERY SYSTEM QUALITY CONTROL

    SBC: Rhomed, Inc.            Topic: N/A

    A QUALITY CONTROL (QC) TEST KIT WILL BE DEVELOPED AND AND VALIDATED FOR USE IN MEASURING THE PERCENTAGE OF IMMUNOREACTIVE RADIOACTIVITY OF RADIOLABELED ANTIBODY OR ANTIBODY FRAGMENTS INTENDED FOR PATIENT USE. THIS QC PRODUCT IS BEING DESIGNED FOR A MULTICENTERED CLINICAL TRIALOF COMPOUNDED, RADIOLABELED ANTIBODIES. PANELS OF CURRENTLYAVAILABLE MONOCLONAL ANTIBODIES (MABS) THAT HAVE POTENTIAL FOR T ...

    SBIR Phase II 1989 Department of Health and Human Services
  4. AN ULTRASONIC PLATELET HARVESTER

    SBC: Technical research Associates, Inc.            Topic: N/A

    TECHNICAL RESEARCH ASSOCIATES, INC. PROPOSES THE DEVELOPMENTOF A NOVEL PLATELET-HARVESTING SYSTEM BASED ON A PREVIOUSLY DEVELOPED ULTRASOUND SEPARATION TECHNOLOGY. THIS TECHNOLOGY, DEVELOPED UNDER AN NHLBI GRANT, ALLOWS THE SEQUENTIAL SEPARATION OF CELLS BASED ON THEIR SIZE, EVEN THOSE CELLS THAT HAVE IDENTICAL DENSITIES. FIRST, RESIDUAL ERYTHROCYTES AND LARGE LEUKOCYTES CAN BE SEPARATED FROM PLAT ...

    SBIR Phase II 1989 Department of Health and Human Services
  5. DIAGNOSTIC IMAGING INSTRUMENT DEVELOPMENT

    SBC: TECHNISCAN, INC.            Topic: N/A

    THE LONG-TERM OBJECTIVE OF THIS PROJECT IS TO DEVELOP A PROTOTYPE SCANNING SYSTEM FROM WHICH NOVEL AND ADVANCED ULTRASOUND SCANNING SYSTEMS CAN BE MANUFACTURED FOR THE IMAGING, TISSUE CHARACTERIZATION, AND DIAGNOSIS OF CANCER AND OTHER DISEASES. IT WILL GIVE SUPERIOR IMAGES OF OBSTETRICAL CONDITIONS, VASCULAR DISEASE, LIVER DISEASE, ANDOTHER ABDOMINAL CONDITIONS. THIS ADVANCED SYSTEM IS BASED ON E ...

    SBIR Phase II 1989 Department of Health and Human Services
  6. LIQUID PROPELLANT PULSED ELECTROTHERMAL THRUSTER

    SBC: Gt-devices Inc            Topic: N/A

    AN ON-ORBIT PROPULSION CAPACITY IS REQUIRED FOR STRATEGIC DEFENSE THATFEATURES HIGH EFFICIENCY AT A SPECIFIC IMPULSE OF 1000-3000 SECONDS. THIS PROPULSION IS REQUIRED FOR ORBIT TRANSFER, ORBITAL MANEUVERING AND STATION-KEEPING MISSIONS. THE PULSED ELECTROTHERMAL (PET) THRUSTER SEEMS PARTICULARLY ATTRACTIVE FOR THESE APPLICATIONS, AND HASPREVIOUSLY APPROACHED THE REQUIRED PERFORMANCE LEVELS WITH WA ...

    SBIR Phase II 1989 Department of DefenseMissile Defense Agency
  7. SOLID LUBRICANTS FOR SPACE STRUCTURES

    SBC: Materials Modifications Inc.            Topic: N/A

    NEW AND INNOVATIVE NONEQUILIBRIUM MATERIALS FOR VARIOUS SPACE STRUCTURES ARE NEEDED FOR STRATEGIC DEFENSE. ONE AREA WHERE LITTLE ATTENTION HAS BEEN FOCUSSED IS THE DEVELOPMENT OF SOLID LUBRICANTS. THE POTENTIAL USE IS BEING EXPLORED OF HIGH LEAD BEARING COPPER ALLOYS(UP TO 50% LEAD) AS BEARING MATERIALS; BATTERY GRIDS THAT WOULD REPLACE THE CURRENTLY USED LEAD ALLOYS; AND POSSIBLE COATINGS FOR HIG ...

    SBIR Phase II 1989 Department of DefenseMissile Defense Agency
  8. MICROSTACK INSULATOR FOR HIGH VOLTAGE PULSED SYSTEMS

    SBC: Tetra Corporation            Topic: N/A

    POLYMERIC OR CERAMIC INSULATORS CONVENTIONALLY ARE BEING USED IN HIGH VOLTAGE PULSED SYSTEMS. NEW APPROACHES ARE NEEDED THAT WOULD REDUCE INSULATORS RING THICKNESSES AND INCREASE CORRESPONDING GRADING RINGS FLASHOVER VOLTAGE. SUCH AN APPROACH WOULD POSSESS IN COMPARISON TO CONVENTIONAL INSULATORS: HIGHER SURFACE FLASHOVER FIELD STRENGTH; SMALLER PHYSICAL DIMENSIONS FOR EQUIVALENT VOLTAGE HOLDOFF; ...

    SBIR Phase II 1989 Department of DefenseMissile Defense Agency
  9. HIGH POWER LOW IMPEDANCE LIGHT WEIGHT TRANSMISSION LINES

    SBC: Tetra Corporation            Topic: N/A

    THE DEVELOPMENT OF HIGH POWER, LOW IMPEDANCE, LIGHTWEIGHT ENERGY STORAGE TRANSMISSION LINES FOR PULSE-POWER APPLICATIONS IS CRUCIAL FORSMALLER, LIGHTWEIGHT, SPACE-BASED, PULSE-POWER SYSTEMS. DEVELOPMENT OF HIGH DIELECTRIC ENERGY STORAGE LINE TECHNOLOGY WOULD GREATLY REDUCETHE SIZE, WEIGHT, AND COMPLEXITY OF PULSE POWER SYSTEMS UTILIZING THESE TYPES OF COMPONENTS. EFFICIENT TRANSPORT OF 400KV, 100K ...

    SBIR Phase II 1989 Department of DefenseMissile Defense Agency
  10. SECONDARY PREVENTION OF ALCOHOLISM VIA COMPUTER SOFTWARE

    SBC: Alcohol Self-control Program            Topic: N/A

    THE OVERALL GOAL OF THIS PROJECT IS TO DEVELOP, EVALUATE, AND DISSEMINATE AN INTERACTIVE COMPUTER SOFTWARE PROGRAM FORSECONDARY PREVENTION OF ALCOHOL ABUSE. SECONDARY PREVENTIONIS DEFINED HERE AS TRAINING IN SPECIFIC BEHAVIORAL SKILLS TO EITHER REDUCE AND/OR ELIMINATE ALCOHOL CONSUMPTION AND ALCOHOL-RELATED PROBLEMS. THE CLINICAL POPULATION THIS TRAINING WILL TARGET CONSISTS OF ALCOHOL ABUSERS WHO ...

    SBIR Phase II 1993 Department of Health and Human Services
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