Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. MONOCLONAL ANTIBODIES TO HUMAN PARAINFLUENZA VIRUES 1 AND 2

    SBC: MOLECULAR ENGINEERING CORP.            Topic: N/A

    MOLECULAR ENGINEERING ASSOCIATES, INC. PROPOSES TO DEVELOP APANEL OF MONOCLONAL ANTIBODIES TO HUMAN PARAINFLUENZA VIRUS TYPES 1 AND 2. ANTIBODIES WILL BE EVALUATED BY NEUTRALIZATION, HEMAGGLUTINATION INHIBITION, NEURAMINIDASE INHIBITION, FUSION INHIBITION, ELISA, IMMUNE PRECIPITATION, WESTERN BLOT, AND IMMUNOFLUORESCENCE ASSAYS. THE OBJECTIVE OF THE PHASE I PROPOSAL IS TO IDENTIFY MONOCLONAL ANTIB ...

    SBIR Phase II 1988 Department of Health and Human Services
  2. PEDIATRIC INTRA-AORTIC BALLOON PUMP

    SBC: Rocky Mountain Research, Inc.            Topic: N/A

    INTRA-AORTIC BALLOON PUMPING (IABP) HAS BECOME A STANDARD TREATMENT MODALITY FOR CARDIOGENIC SHOCK IN ADULTS BUT HAS BEEN USED ONLY SPARINGLY IN INFANTS. THIS IS DUE IN PART TOTHE LIMITATIONS OF THE CURRENTLY AVAILABLE DRIVE SYSTEMS, WHICH ARE DESIGNED TO MEET THE PHYSIOLOGIC NEEDS OF AN ADULT. A BALLOON PUMP, SPECIFICALLY TAILORED TO THE SMALL VOLUMES AND HIGHER RATES OFTEN SEEN IN PEDIATRIC CASE ...

    SBIR Phase II 1988 Department of Health and Human Services
  3. URINARY INCONTINENCE DEVICE

    SBC: Technical research Associates, Inc.            Topic: N/A

    A FOUR-ELEMENT FEASIBILITY STUDY IS PROPOSED TO EVALUATE A NOVEL IDEA FOR PROVIDING URINARY BLADDER CONTINENCE TO INCONTINENT INDIVIDUALS, ESPECIALLY THE AGED. THE DEVICE IS A NONSURGICALLY INSERTED FLEXIBLE SEAL. MICTURITION CAN BE INITIATED BY AN EXTERNAL SEAL CONTROLLER. BECAUSE THE DEVICE CAN BE INSERTED INTO THE BLADDER THROUGH A UROCATHETER, SURGERY IS NOT REQUIRED. THE PHASE I FEASIBILITY S ...

    SBIR Phase II 1988 Department of Health and Human Services
  4. ENHANCED CENTRIFICATION DEVICES

    SBC: Technical research Associates, Inc.            Topic: N/A

    IT IS PROPOSED TO APPLY NOVEL ULTRASOUND TECHNOLOGY TO THE DEVELOPMENT OF IMPROVED CENTRIFUGATION EQUIPMENT. THIS NEW DEVICE WILL USE INCLINED SURFACES IN CONJUNCTION WITH ULTRA-SOUND FORCE FIELDS TO SUBSTANTIALLY INCREASE SEDIMENTATION. BECAUSE THIS EQUIPMENT CAN PRODUCE EQUIVALENT SEPARATION WITH LOWER ACCELERATIONS (LOWER CENTRIFUGE ROTATIONAL VELOC-ITY), DESIGN OF A PRACTICAL CONTINUOUS-FLOW C ...

    SBIR Phase II 1988 Department of Health and Human Services
  5. EVALUATION OF RETROVENOUS MYOCARDIAL DRUG DELIVERY SYSTEM

    SBC: Utah Biomedical Test Labs            Topic: N/A

    THE FEASIBILITY OF RETROVENOUS MYOCARDIAL DRUG DELIVERY (XYLOCAINE) TO TREAT AND CONTROL ARRHYTHMIAS WILL BE TESTED IN SHEEP AFTER CORONARY ARTERY OCCULSION, AND THEN COMPARED TO THE STANDARD INTRAVENOUS ROUTE. ENDPOINTS OF NUMBER AND TYPE OF ARRHYTHMIAS, XYLOCAINE DOSE, PLASMA, AND MYOCARDIAL XYLOCAINE CONCENTRATIONS WILL BE DETERMINED. THE DEMONSTRA-TION OF THE HYPOTHESIS THAT RETROVENOUS MYOCAR ...

    SBIR Phase II 1988 Department of Health and Human Services
  6. DESIGN AND EVALUATION OF A COMPOUND TRACHEAL PROSTHESIS

    SBC: Utah Biomedical Test Labs            Topic: N/A

    THE PROPOSED STUDY IS DESIGNED TO DEVELOP AND EVALUATE A METHOD OF REPLACING THE TRACHEA WITH A COMPOUND PROSTHESIS THAT WILL BE EPITHELIZED AT THE TIME OF IMPLANTATION BY TISSUE CULTURE OF BUCCAL MUCOSA OR A FREE GRAFT OF TRACHEAL MUCOSA. HEALING OF THE CERVICAL TRACHEA TO TWO TYPES OF PROSTHESES WILL BE EVALUATED IN DOGS. BOTH TYPES WILL HAVE A RIGID POLYETHYLENE OUTER LAYER AND A MIDDLE LAYER O ...

    SBIR Phase II 1988 Department of Health and Human Services
  7. CRYOCOOLER FOR HIGH ACCELERATION SYSTEMS

    SBC: Alabama Cryogenic Engineering, Inc.            Topic: N/A

    A CRYOCOOLER CAPABLE OF OPERATING UNDER EXTREMELY HIGH ACCELERATION LEVELS IS PROPOSED. THE CRYOCOOLER USES THE LINDE-HAMPSON CYCLE, AND CAN REACH APPROXIMATELY 80 KELVIN. MULTI-STAGE UNITS, TO REACH LOWER TEMPERATURES, ARE ALSO POSSIBLE.

    SBIR Phase II 1988 Department of DefenseMissile Defense Agency
  8. KINETIC ENERGY WEAPONS

    SBC: Nichols Research Corp            Topic: N/A

    THE ACQUISITION OF POST BOOST PHASE VEHICLES AND/OR INDIVIDUAL REENTRY VEHICLES BY AN INFRARED SENSOR ON BOARD A SMALL G HARDENED PROJECTILE WHICH SUBSEQUENTLY HOMES ON AND IMPACTS ITS TARGET OFFERS AN ATTRACTIVE APPROACH FOR REENTRY VEHICLE KINETIC ENERGY KILL. THE ACQUISITION, TRACKING, DISCRIMINATION AND GUIDANCE FUNCTIONS REQUIRED OF SUCH AN IR SENSOR RESULT IN A NUMBER OF CRITICAL ISSUES. THE ...

    SBIR Phase II 1988 Department of DefenseMissile Defense Agency
  9. HIGH REPETITION RATE GLOW DISCHARGE CLOSING SWITCH DEVELOPMENT PROGRAM

    SBC: Tetra Corporation            Topic: N/A

    THE DEVELOPMENT OF HIGH POWER, HIGH REPETITION RATE CLOSING SWITCHES HAS RECENTLY BECOME IMPORTANT FOR MANY PULSED POWER APPLICATIONS. HISTORICALLY, HIGH REPETITION RATE SWITCHES FOR PULSED POWER APPLICATIONS HAVE EITHER BEEN SPARK GAPS OR THYRATRONS. THYRATRONS HAVE HIGH REPETITION RATES, BUT ARE LIMITED TO LOW VOLTAGES AND LOW CURRENT. CONVERSELY, SPARK GAPS CAN CARRY HIGH CURRENTS AND STAND-OFF ...

    SBIR Phase II 1988 Department of DefenseMissile Defense Agency
  10. ENHANCED ELF COMPUTER CODES DEVELOPMENT

    SBC: Tetra Corporation            Topic: N/A

    MANY OF THE SYSTEMS FOR SDI INVOLVE PULSE POWER AND HIGH VOLTAGE SYSTEMS, INCLUDING LASERS, PARTICLE BEAM ACCELERATORS, AND RAILGUNS. ONE OF THE SIGNIFICANT PROBLEMS YET TO BE SOLVED IN DEVELOPING OPERATIONAL SDI SPACECRAFT IS THE MANAGEMENT OF ELECTRIC FIELDS WITHIN THE SPACECRAFT, THE PRIMARY WEAPON SYSTEM, AND ITS POWER SUPPLY AND CONDITIONING EQUIPMENT. THE ELF CODES UNIQUELY HAVE THE ABILITY ...

    SBIR Phase II 1988 Department of DefenseMissile Defense Agency
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