Award Data

A SMALLER, LIGHTER, MORE EFFICIENT, AND MORE RELIABLE CLINICAL GAS ANALYZER FOR RESPIRATORY AND ANESTHETIC GAS MONITORING IS NEEDED. EXISTING LASER RAMAN-BASED INSTRUMENTATION USES A LARGE, HEAVY, AND EXTREMELY INEFFICIENT (0.1 PERCENT) ARGON ION LASER WITH AN INTRACAVITY GAS CELL. THE LONG-TERM OBJECTIVE OF THIS STUDYIS TO IMPLEMENT A SOLID-STATE ALTERNATIVE TO THE EXISTING ION LASER. SUCH A LASE ...

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QUADRIPLEGICS HAVE SPECIAL COMMUNICATION NEEDS. THE OBJECTIVE OF THE WIRELESS INFRARED NICTATING COMMUNICATION SYSTEM (WINCS) PROJECT IS TO DEMONSTRATE THE FEASIBILITY OF A SPEAKER-TYPE TELEPHONE THAT COULD BE OPERATED DIRECTLY BY EYEBLINKS. A MICROPHONE ATTACHED TO THE SPEAKERPHONE WILL ALLOW THE USER TO CONTROL SUCH FUNCTIONS AS ANSWERING, HANGING UP, AND DIALING. A MEMORY DEVICE WILL BE INCORPO ...

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FLOW/STERIC FIELD-FLOW FRACTIONATION (FLOW/STFFF) IS A RECENTLY DEVELOPED METHOD WITH EXTRAORDINARY SPEED AND RESOLVING POWER DESIGNED TO SEPARATE PARTICULATE MATERIALS FALLING ROUGHLY IN THE 1 TO 100 MUM PARTICLE DIAMETER RANGE. THE OBJECT OF THIS PROJECT IS TO EXAMINE THE POTENTIAL OF CONVERTING THIS RESEARCH FINDING INTO A FAST AND RELIABLE TOOL FOR THE FRACTIONATION AND CHARACTERIZATIONOF CELL ...

FREE TISSUE TRANSFER HAS REVOLUTIONIZED MANY AREAS OF RECONSTRUCTIVE SURGERY. AS FREE TISSUE TRANSFER IS NOW BEING DONE ROUTINELY AT INSTITUTIONS WHERE INEXPERIENCED STAFF ARE UNABLE TO ADEQUATELY MONITOR VIABILITY, THE NEED FOR A RELIABLE METHOD TO MONITOR THE PATENCY OF MICROVASCULAR ANASTOMOSES HAS BECOME INCREASINGLY EVIDENT. ACCURATE MONITORING OF BLOOD FLOW DURING AND AFTER SURGERY IS ESSENT ...

THE APPLICATION OF PHYSICAL-CHEMICAL PRINCIPLES TO BIOLOGICAL SYSTEMS FREQUENTLY LEADS TO SITUATIONS IN WHICH THE QUANTITATIVE TREATMENT OF CONCEPTUALLY SIMPLE MODELS IS CONFOUNDED BY THE COMPLEXITY OF THE SYSTEM. SUCH IS THE CASE, FOR EXAMPLE, IN THE STUDY OF THE PERMEATION (AND POSSIBLE CONCURRENT METABOLISM) OF DRUGS THROUGH COMPLEX BIOLOGICAL MEMBRANES, THE PHYSIOLOGICAL MODELING OF THE DISTRI ...

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THE AIM OF THIS PROJECT IS TO EVALUATE THE FEASIBILITY OF DEVELOPING ANALYTICAL TECHNOLOGY APPLICABLE TO THE DETERMINATION OF DESMOSINE (DMS) IN THE SYSTEMATIC CIRCULATORY SYSTEM AND IN OTHER PHYSIOLOGICAL SAMPLES. IN VIVO HYDROLYTIC DEGRADATION OF THE CONNECTIVE TISSUE ELASTINBY THE ENZYME ELASTASE PRODUCES DMS-PEPTIDE FRAGMENTS. CURRENT RESEARCH SUGGESTS THAT AN ACCURATE DETERMINATION OF DMS-PEP ...