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Award Data
The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Rapid Monitoring and Assessment of Tubercuolosis Treatment at the Point of Care Using Breath
SBC: NanoSynth Materials and Sensors Inc. Topic: NHLBIDESCRIPTION provided by applicant Problem and Significance According to the CDC global statistics nearly of the world is infected with Tuberculosis TB In million f peopled infected lived in what is considered a high burden country Countries such as India Peru China sub Saharan Africa and others have significant regions endemic for TB particularly among the lower income ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Highly specific anti-toxin therapies for severe bacterial gut infections
SBC: NAVIGEN, INC. Topic: RDESCRIPTION provided by applicant Shiga toxins and Stx are the primary virulence factors of Shiga toxin producing E coli STEC which are major food and waterborne pathogens afflicting both developed and developing countries An estimated STEC infections occur annually in the US In addition to severe and often bloody diarrhea the life threatening complication hemolytic ur ...
SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Arf6 inhibitors for the treatment of uveal melanoma
SBC: NAVIGEN, INC. Topic: 102DESCRIPTION provided by applicant Activating mutations in G proteins are the drivers of oncogenesis in numerous cancers Therefore identifying drugs that block the signaling pathways controlled by these mutations could have enormous therapeutic consequences Uveal melanoma is a prototypical G driven cancer in which about of tumors have activating mutations in one of two G encoding genes ...
SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Targeted Intraceptor Nanoparticle for Macular Degeneration
SBC: Iveena Delivery Systems, Inc. Topic: NDESCRIPTION provided by applicant Age related macular degeneration AMD is a leading cause of blindness in United States and many other industrialized nations There are two types of AMD the andquot dryandquot and andquot wetandquot forms Dry AMD is a chronic disease that usually causes variable degree of visual impairment In contrast in wet AMD which affects of AMD patients t ...
SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Treating Acute Lung Injury via Cytokine Signaling Blockade
SBC: NAVIGEN, INC. Topic: NHLBIDESCRIPTION provided by applicant Acute lung injury ALI and acute respiratory distress syndrome ARDS result from a common pathogenic process pulmonary injury or infection triggers an overwhelming inflammatory response andquot cytokine stormandquot that results in increased endothelial and epithelial permeability and efflux of inflammatory cells protein and water from the vascular syst ...
SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Hand-held advanced functional imager for assessing local tissue oxygenation
SBC: WASATCH PHOTONICS, INC. Topic: NHLBIDESCRIPTION provided by applicant We propose development of an advanced functional imager to assess red blood cell RBC transfusion The prototype will be tested in a functional phantom during this SBIR Phase I project The key features of the imager are the ability to quantify local tissue oxygenation with a handheld probe for easy tissue access Our preliminarily market research indicates a ...
SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
HLS13-04 High-Content High-Throughput Screen for Diamond Blackfan Anemia Treatments
SBC: Recursion Pharmaceuticals, LLC Topic: NHLBIDESCRIPTION provided by applicant There are thousands of rare genetic diseases that have no approved treatment Recursion Pharmaceuticals has developed a drug discovery platform that seeks to re purpose known drugs for the treatment of such diseases The platform consists of high content immunofluorescent image analysis using machine learning algorithms to identify relevant and on target chang ...
SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Application of an efficient drug repurposing platform to identify treatments for Cornelia De Lange Syndrome
SBC: Recursion Pharmaceuticals, LLC Topic: NICHDDESCRIPTION provided by applicant Cornelia de Lange Syndrome is a complex congenital malformations syndrome with many post natal progressive medical complications CdLS has a clear genetic cause with loss of function mutations in NIPBL accounting for over of the genetically confirmed CdLS cases The remaining cases exhibit mutations in subunits or regulators of the cohesion complex SMC S ...
SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Protease resistant D peptide Inhibitors of Ebola Virus Entry
SBC: NAVIGEN, INC. Topic: RDESCRIPTION provided by applicant Ebola virus causes highly lethal hemorrhagic fever in humans and non human primates Since the first outbreak in there have been over natural human outbreaks with an average mortality rate near There are no approved agents to prevent or treat Ebola infection Due to ease of dissemination high lethality and ability to cause widespread panic the ...
SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health -
HT Label-Free Screening and Kinetic Analysis of Small Molecules and Biologics
SBC: Carterra, Inc. Topic: 100DESCRIPTION provided by applicant Real time label free technologies such as surface plasmon resonance biosensors provide high resolution information about the kinetics affinity stoichiometry activity and specificity of two or more binding partners While the application f biosensors is well established current instrumentation has limited sampling throughput Screens of even a fairly sma ...
SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health