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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Signal Processing/Automation for Cardiac Output Monitor

    SBC: Axon Medical Inc            Topic: N/A

    Thermal dilution is by far the most common method of measuring cardiac output. Over onemillion thermodilution pulmonary artery catheters are used each year in the U.S. We have appliedartificial neural networks to improve the accuracy of the thermal dilution cardiac output measurementand allow using small injectate volumes (2 ml). We will build an automated system using a modifiedsyringe pump and a ...

    SBIR Phase I 1994 Department of Health and Human Services
  2. Stand Alone Uterine Manipulator

    SBC: Clinical Innovations, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1994 Department of Health and Human Services
  3. Pediatric Computerized Severity Index

    SBC: Int'l Severity Information            Topic: N/A

    N/A

    SBIR Phase I 1994 Department of Health and Human Services
  4. Development of GD DTPA Bisglucosamide for MRI Contrast

    SBC: Magnetic Research, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1994 Department of Health and Human Services
  5. Quantitative Assessment of Microembolic Involvement

    SBC: MEDICAL PHYSICS, INC.            Topic: N/A

    We will establish the feasibility for applying a new and noninvasive method to the developmentof a practical instrument for sensitive and quantitative detection of microembolic involvement in humanlungs. Because present methods for detection of pulmonary emboli utilize imaging techniques, the sizeof emboli detectable by these methods are limited by the inherent spacial resolution of x-ray and gamm ...

    SBIR Phase I 1994 Department of Health and Human Services
  6. AN OPERATING ENVIRONMENT FOR SCIENTIFIC COMPUTING

    SBC: Micromath Inc.            Topic: N/A

    INITIAL DESIGN AND TESTING OF THE MICROMATH SCIENTIFIC COMPUTING ENVIRONMENT (MMSCE) WILL BE CARRIED OUT. THE MMSCE EMBODIES AN OBJECT ORIENTED APPROACH TO SCIENTIFIC COMPUTING. "COMPUTATIONAL NODES" ARE DEFINED HERE AS ENTITIES BETWEEN WHICH DATA AND OTHER MESSAGES FLOW. IN THE MMSCE, THE SCENTIST-USER MANIPULATES COMPUTATIONAL NODES, AUTOMCATICALLY LINKING POTENTIALLY DIVERSE TYPES OF SCIENTIFIC ...

    SBIR Phase II 1994 Department of Health and Human Services
  7. Externally Powered Hand Orthosis--High Mobility Wrist

    SBC: MOTION CONTROL, INC            Topic: N/A

    Our purpose is to develop orthotic devices that will improve hand function for people withparalyzed upper limbs. Existing devices that allow for some hand function for people with paralyzedupper limbs are based on the World Health Organization 1954 tenodesis orthotic splint. Developmentsover the past decade have provided the possibility for devising orthoses that can be controlled by signalsfrom s ...

    SBIR Phase I 1994 Department of Health and Human Services
  8. NMDA Receptor Antagonists That Spare LTP

    SBC: NPS Pharmaceuticals, Inc.            Topic: N/A

    The N-methyl-D-aspartate (NMDA) subtype of glutamate receptor has been implicated in avariety of neurological pathologies including ischemic brain damage (stroke), head trauma, spinal cordinjury, epilepsy, neurodegenerative disorders such as Alzheimer's Disease, and hyperalgesic states. Thedevelopment of NMDA antagonists as therapeutants, however, has been hampered by the occurrenceof deleterious ...

    SBIR Phase I 1994 Department of Health and Human Services
  9. NONINSTRUMENTED RAPID, QUANTITATIVE BLOOD-HEPARIN ASSAY

    SBC: Researh Medical, Inc.            Topic: N/A

    N/A

    SBIR Phase II 1994 Department of Health and Human Services
  10. Continuous Cardiac Output Determination

    SBC: Rocky Mountain Research, Inc.            Topic: N/A

    Thermal dilution, the most common method used for determining cardiac output, is highlytechnique dependant and yields results that may be off as much as +/- 2O%. To reduce error, theprocedure is often repeated a number of times and the average of all of the readings taken. Each readingrequires a bolus injection of solution, increasing the risk of sepsis and fluid overload. Modifications tothis tec ...

    SBIR Phase I 1994 Department of Health and Human Services

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