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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Heartland Infrastructure Development Bank

    SBC: CEO Praxis Inc            Topic: N/A

    Infrastructure investment has been crucial to economic development throughout American history. Today there is a need for a sizeable investment in infrastructure, particularly in rural America and especially with respect to transportation and telecommunications. New facilities to distribute food and energy resources to the rest of the country will be needed. There is also a need for investment in ...

    SBIR Phase I 2008 Department of Agriculture
  2. Tribal Leaders Institute: On-line Training for Indian Nations

    SBC: SPIRIT LAKE CONSULTING, INC.            Topic: N/A

    The Department of the Interior alone appropriates over $2 billion dollars each year for the Operation of Indian Programs. This figure does not include billions of dollars that come into each reservation through grant funds from other agencies, private philanthropy, the $14.1 billion brought in from tribal gaming or other tribal enterprises. Much of this money never reaches its intended recipients, ...

    SBIR Phase II 2008 Department of Agriculture
  3. Utility Arm and Upper Limb Prosthesis

    SBC: MOTION CONTROL, INC            Topic: N/A

    This project develops an innovative upper extremity (UE) prosthetic system which offerssubstantial improvement in functionality, ruggedness, and comfort for persons with limb deficiencies attransradial, elbow, and transhumeral levels. Called ¿Utility Arm,¿ the system of improved componentsis designed to increase independence and work capabilities for users of arm prostheses.

    SBIR Phase I 2008 Department of Education
  4. Clinical Evaluation of a Rebreathing Adsorber Mask to Facilitate Recovery from Vo

    SBC: Axon Medical Inc            Topic: N/A

    DESCRIPTION (provided by applicant): After surgery patients are transferred to a post anesthesia care unit to fully recover from anesthesia. There is a much higher chance of an adverse clinical event occurring during this recovery time (24%) than in the op erating room because patients are not as closely monitored. Airway obstruction is the most frequent complication. Patients with a critical resp ...

    SBIR Phase I 2008 Department of Health and Human Services
  5. Minimally-Invasive Image-Guided Therapy for Cancer Treatment

    SBC: CONTRADYN, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term objective of this research is to develop a technology and eventually a minimally-invasive commercial system for image-guided photodynamic therapy for cancer. This is certainly in keeping with NCI's focus o n imaging in vivo for cancer screening, diagnosis, progression, image-guide therapy, treatment monitoring, and recurrence. In studies conducted ...

    STTR Phase I 2008 Department of Health and Human Services
  6. Methylerythritol Phosphate Pathway-Specific Natural Products as Antibacterials

    SBC: ECHELON BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term objective of this project is to identify a new class of antibiotics targeting the methylerythritol phosphate (MEP) pathway, a novel pathway essential for the viability of all Gram-negative and many Gram- p ositive bacteria. Gram-negative bacteria are responsible for more than half of hospital acquired (nosocomial) infections which cost an estimate ...

    SBIR Phase I 2008 Department of Health and Human Services
  7. Discovery of Inositol(1,4,5)trisphosphate Receptor Inhibitors

    SBC: ECHELON BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Stroke has become a significant cause of mortality and morbidity among elderly people in industrialized countries. To address the growing burden of health care costs and the immeasurable emotional toll on families as we ll as affected individuals, new pharmacological agents for prevention and treatment are desperately needed. Oxygen deprivation and oxidative st ...

    SBIR Phase I 2008 Department of Health and Human Services
  8. Fluorogenic Assays for Measuring the Activity of Ceramidase and Sphingomyelinase

    SBC: ECHELON BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Sphingolipids are a class of lipids that have important roles as structural components of cell membranes yet are also key signaling molecules involved in numerous cellular processes such as apoptosis, cell survival, dif ferentiation, motility, and growth. The levels of the various sphingolipids are kept in balance by metabolizing enzymes and disruptions by abno ...

    SBIR Phase I 2008 Department of Health and Human Services
  9. Methylerythritol Phosphate Pathway Inhibitors Targeting Gram-Negative Infections

    SBC: ECHELON BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term objective of this project is to identify a new class of antibiotics targeting an underexploited pathway essential for the viability of all Gram-negative bacteria, the methylerythritol phosphate (MEP) pathw ay. Gram-negative bacteria are responsible for more than half of hospital acquired (nosocomial) infections which cost an estimated 5 billion d ...

    SBIR Phase I 2008 Department of Health and Human Services
  10. Snapback Primers for Genotyping and Mutation Scanning

    SBC: IDAHO TECHNOLOGY            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this Fast-Track STTR is to develop a simple, inexpensive, closed-tube PCR method for genotyping and sequence variant scanning. Instead of covalently-labeled probes, one of two primers includes a tail w ith a probe element. After asymmetric PCR, this tail anneals internally to the same strand, snapping back , to form a stem/loop structure. Bot ...

    STTR Phase II 2008 Department of Health and Human Services

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