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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Novel Process for Production of Fatty Acids from Lignocellulosic Biomass

    SBC: Technology Holding, LLC            Topic: 88

    This Small Business Innovation Research Phase II project will demonstrate techno-economic feasibility of a novel bioprocess to produce fatty acids from lignocellulosic biomass leading to commercialization. These fatty acids are primary components of several consumer products such as skincare, cosmetics, soaps, shampoos and vitamins. The proposed process utilizes metabolically engineered E. coli cu ...

    SBIR Phase II 2013 Department of Agriculture
  2. Automated Dynamic Lists for Efficient Electronic Health Record Management

    SBC: Clinacuity, Inc            Topic: NCI

    DESCRIPTION (provided by APPLICANT): Medical errors are recognized as the cause of numerous deaths, and even if some are difficult to avoid, many are preventable. Computerized physician order-entry systems with decision support have been proposed to reducethis risk of medication errors, but these systems rely on structured and coded information in the electronic health record (EHR). Unfortunately, ...

    STTR Phase I 2013 Department of Health and Human Services
  3. Evaluation of the Antigenicity of Black Restricted FVIII Haplotypes and Haplotype

    SBC: Haplomics            Topic: NIMHD

    Evaluation of the Antigenicity of Black-Restricted Haplotypes of Factor VIII ABSTRACT About 30% of congenital Hemophilia A (HA) patients develop alloantibodies that neutralize the activity of replacement Factor (F) VIII proteins. Such patients, who are termed inhibitor patients, are typically treated with so called bypassing agents such as recombinant (r) FVIIa and FEIBA. Bypassing agents are mor ...

    STTR Phase I 2013 Department of Health and Human Services
  4. High-specificity affinity reagents for N-glycosylation site mapping and glycomics

    SBC: GLYCOSENSORS AND DIAGNOSTICS, LLC            Topic: NIGMS

    DESCRIPTION: Glycans have several distinct properties that make them excellent targets for disease biomarkers. Firstly, the location of the glycans on the cell surface makes them the first point of contact of cellular interactions and thus crucial in thecontrol of normal metabolic processes. Cell surface molecules are also strategically exposed for surveillance by the immune system allowing for t ...

    STTR Phase II 2013 Department of Health and Human Services
  5. Reduce the Risk: An Affect Management Program for HIV Prevention

    SBC: VIRTUALLY BETTER INC            Topic: NIMH

    DESCRIPTION (provided by applicant): The proposed project, titled Reduce the Risk: An Affect Management Program for HIV Prevention, will examine the use of immersive virtual reality technology as an intervention tool for HIV Prevention with adolescents. Adolescents are at risk for contracting HIV. Affect dysregulation is common among adolescents. Research has demonstrated connections between poor ...

    STTR Phase II 2013 Department of Health and Human Services
  6. System for multidimensional analysis of growth and migration of neurons and neuro

    SBC: INHIBIKASE THERAPEUTICS            Topic: NIAID

    DESCRIPTION (provided by applicant): Inhibikase Therapeutics is a clinical stage, biopharmaceutical company that has developed a host- targeted mechanism of action to treat AIDS-related and drug-induced progressive multifocal leukoencephalopathy (PML). PMLis a demyelinating disease of the central nervous system and was rarely seen clinically until the era of the HIV epidemic began in the mid-1980s ...

    SBIR Phase I 2013 Department of Health and Human Services
  7. Rapid, automated, detection of viral and bacterial pathogens causing meningitis

    SBC: IDAHO TECHNOLOGY            Topic: NIAID

    DESCRIPTION (provided by applicant): Meningitis and encephalitis are inflammatory, often infectious, processes of the central nervous system that can result in significant morbidity and mortality. Prompt, appropriate therapy is crucial, but determining theinfectious etiology can be difficult and time-consuming. A wide-range of pathogens can be involved including both bacteria and viruses. Culture ...

    SBIR Phase I 2013 Department of Health and Human Services
  8. Drug Resistant HIV: Novel Target Validation and Small Molecule Lead Discovery

    SBC: GEOVAX, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): HIV/AIDS remains a major health problem and there is a need for effective and durable HIV vaccines. Establishing potent and durable antibodies (Ab) that have neutralizing and non-neutralizing mechanisms can contribute to the prevention of mucosal HIV infection. Findings from the recent RV144 trial have highlighted a significant role for protective non-neutraliz ...

    SBIR Phase I 2013 Department of Health and Human Services
  9. CT-based Biomarker for Diagnosis of COPD Phenotypes and Disease Progression

    SBC: NAVIGEN, INC.            Topic: NIAMS

    DESCRIPTION (provided by applicant): Rheumatoid arthritis (RA) affects approximately 1.3 million adults in the United States and up to 1.5% of the population worldwide. In its progressive form the disease has debilitating effects including painful inflammation and destruction of the joints. This affliction leads to considerable lost work and disability. A hallmark of the RA inflammatory respon ...

    SBIR Phase I 2013 Department of Health and Human Services
  10. Intraoperative imaging of breast cancer margins using Polarization Subtraction Te

    SBC: LUMAMED, LLC            Topic: NCI

    DESCRIPTION (provided by applicant): LumaMed LLC proposes developing LumaScan , an innovative, cost effective and easy to use device for visualizing tumor margins during Breast Conservation Surgery (BCS), a method that is used in about 60-70% percent of breast cancer surgeries. Currently, breast tumors are approximately located using methods such as MRI or CT in a preoperative procedure. During s ...

    SBIR Phase I 2013 Department of Health and Human Services

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