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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Novel Process for Production of Fatty Acids from Lignocellulosic Biomass

    SBC: Technology Holding, LLC            Topic: 88

    This Small Business Innovation Research Phase II project will demonstrate techno-economic feasibility of a novel bioprocess to produce fatty acids from lignocellulosic biomass leading to commercialization. These fatty acids are primary components of several consumer products such as skincare, cosmetics, soaps, shampoos and vitamins. The proposed process utilizes metabolically engineered E. coli cu ...

    SBIR Phase II 2013 Department of Agriculture
  2. Automated Dynamic Lists for Efficient Electronic Health Record Management

    SBC: Clinacuity, Inc            Topic: NCI

    DESCRIPTION (provided by APPLICANT): Medical errors are recognized as the cause of numerous deaths, and even if some are difficult to avoid, many are preventable. Computerized physician order-entry systems with decision support have been proposed to reducethis risk of medication errors, but these systems rely on structured and coded information in the electronic health record (EHR). Unfortunately, ...

    STTR Phase I 2013 Department of Health and Human Services
  3. Rapid, automated, detection of viral and bacterial pathogens causing meningitis

    SBC: IDAHO TECHNOLOGY            Topic: NIAID

    DESCRIPTION (provided by applicant): Meningitis and encephalitis are inflammatory, often infectious, processes of the central nervous system that can result in significant morbidity and mortality. Prompt, appropriate therapy is crucial, but determining theinfectious etiology can be difficult and time-consuming. A wide-range of pathogens can be involved including both bacteria and viruses. Culture ...

    SBIR Phase I 2013 Department of Health and Human Services
  4. CT-based Biomarker for Diagnosis of COPD Phenotypes and Disease Progression

    SBC: NAVIGEN, INC.            Topic: NIAMS

    DESCRIPTION (provided by applicant): Rheumatoid arthritis (RA) affects approximately 1.3 million adults in the United States and up to 1.5% of the population worldwide. In its progressive form the disease has debilitating effects including painful inflammation and destruction of the joints. This affliction leads to considerable lost work and disability. A hallmark of the RA inflammatory respon ...

    SBIR Phase I 2013 Department of Health and Human Services
  5. Identification of novel small molecule inhibitors of Arf6 for the treatment of va

    SBC: NAVIGEN, INC.            Topic: NEI

    DESCRIPTION (provided by applicant): Age-Related Macular Degeneration is the most common cause of legal blindness in people over 60, affecting an estimated 1.6 million patients. Additionally, over 400,000 diabetic Americans are diagnosed each year with vision-threatening retinal edema and/or neovascularization. The main therapeutic strategies that have been successful to date have focused on reduc ...

    SBIR Phase I 2013 Department of Health and Human Services
  6. AccuTemp Sensor: Radiometry based non-invasive continuous core body temperature m

    SBC: THERMIMAGE, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Accurate measurement of core body temperature during surgery as well as in critical care is imperative to a positive outcome and ongoing quality of life for patients. Core temperature management of patients during extended anesthesia such as cardio-pulmonary bypass (CPB) surgery is equally important, yet there is no accurate core body measurement device availab ...

    SBIR Phase I 2013 Department of Health and Human Services
  7. Reducing Gait Asymmetry in Lower-LImb Amputees Using Real-Time Rehab to Train-to-

    SBC: Veristride, Inc.            Topic: NICHD

    DESCRIPTION (provided by applicant): This Small Business Innovation Research Phase I project seeks to demonstrate the feasibility of a novel device for rehabilitation in the home environment, by using wireless instrumentation and smartphone technology forfeedback to amputees about their real-time performance in situ. The mission of Veristride is to improve the mobility and quality of life of pers ...

    SBIR Phase I 2013 Department of Health and Human Services
  8. Wearable muscle fiber excitation system for preventing blood clot

    SBC: GRADIENT BIOMODELING, LLC            Topic: NIMH

    DESCRIPTION (provided by applicant): Schizophrenia is a complex psychiatric disorder with a heterogeneous clinical phenotype. It is probably one of the most costly psychiatric illnesses, yet the development of novel and safe antipsychotics lags behind. Amplifying the actions of endocannabinoids by inhibiting their enzymatic degradation has emerged as an alternative strategy to exploit the endocann ...

    SBIR Phase I 2013 Department of Health and Human Services
  9. HIGHLY CUSTOMIZABLE BLACKROCK MICRO MOLDED ARRAYS (BRMMA)

    SBC: BLACKROCK MICROSYSTEMS            Topic: NINDS

    DESCRIPTION (provided by applicant): In the last two decades though the field of neuroprosthetics has gained tremendous momentum through the development of novel architectures for neural interfaces, however, till date there is no device which can be nomenclatured as the gold standard in the field. As a result the research and technology environment at each laboratory is unique and require a high ...

    SBIR Phase I 2013 Department of Health and Human Services
  10. Microbial Platform for Accessing Plant Alkaloids

    SBC: BLACKROCK MICROSYSTEMS            Topic: NINDS

    DESCRIPTION (provided by applicant): In order to successfully use microelectrode arrays for stimulation in chronic implantation, the neural electrode must have longevity and efficacy. Efficacy of stimulation primarily means injecting enough charge to the targeted tissue to elicit action potentials. However, in doing so, the electrode itself must not (1) degrade, (2) generate harmful substances and ...

    SBIR Phase I 2013 Department of Health and Human Services

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