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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. INFLATABLE STRUCTURES FOR ENHANCED SIDE IMPACT CRASH PROTECTION

    SBC: Collison Safety Engineer Inc            Topic: N/A

    THIS PROPOSAL DESCRIBES A SIX-MONTH PROGRAM FOR THE INVESTIGATION INTO THE TECHNICAL FEASIBILITY OF A DEPLOYABLE, DOOR-MOUNTED PAD FOR ENHANCING THE PROTECTION LEVEL AFFORDED FRONT SEAT OCCUPANTS BY VEHICLES STRUCK IN THE SIDE DOOR AREA. THE CONCEPT PROPOSED FOR INVESTIGATION IS AN INFLATABLE STRUCTURE INTEGRATED INTO A PRODUCTION-CONFIGURED SMALL CAR DOOR. UPON IMPACT OF THE DOOR A STORED GAS OR ...

    SBIR Phase I 1987 Department of Transportation
  2. INSECT ANTIFEEDANT SALANNIN, A MODEL FOR A NEW COMMERCIAL INSECT CONTROL AGENT

    SBC: Native Plants Inc.            Topic: N/A

    SALANNIN (C34H4O9) IS A PLANT TETRANORTRITERPENOID OCCURRINGIN TWO SPECIES IN THE MELIACEAE, AZADIRACHTA INDICA A. JUSS.(NEEM) AND MELIA DUBIA CAV. SALANNIN HAS BEEN SHOWN TO BE AN ANTIFEEDANT (FEEDING INHIBITOR) AGAINST SEVERAL SPECIES OF INSECT PEST, INCLUDING DIPTERANS (FLIES), LEPIDOPTERANS (CATERPILLARS), AND COLEOPTERANS (BEETLES). WE PLAN TO INVESTIGATE THE FEASIBILITY OF MODELING A NEW CHE ...

    SBIR Phase I 1987 Department of Agriculture
  3. USE OF TRANSPOSABLE ELEMENTS AND RFLP MAPPING TO CLONE QUANTITATIVE TRAIT LOCI

    SBC: Native Plants Inc.            Topic: N/A

    THIS PROPOSED RESEARCH REPRESENTS A UNIQUE COMBINATION OF TECHNOLOGIES AND SUBSEQUENT OPPORTUNITY TO EXAMINE THE MOLECULAR BASIS OF TRAITS EXHIBITING QUANTITATIVE EXPRESSIONAND INHERITANCE. IT HAS BEEN OBSERVED THAT THERE ARE OFTEN STRONG ASSOCIATIONS BETWEEN PATTERNS OF VARIATION OF ISOZYME MARKERS AND PLANT MORPHOLOGICAL CHARACTERS WHICH SHOW QUANTITATIVE INHERITANCE. RECENTLY, HELENTJARIS, EDWA ...

    SBIR Phase I 1987 Department of Agriculture
  4. RAMAN SCATTERING FOR CLINICAL GAS DIAGNOSIS

    SBC: Biomaterials International Inc            Topic: N/A

    THIS PROJECT ADDRESSES THE DEVELOPMENT AND EVALUATION OF A PROTOTYPE LASER RAMAN SCATTERING GAS SENSOR. POTENTIAL APPLICATION AREAS ARE: BLOOD PO2/PCO2 VIA SUITABLE SAMPLING CATHETER AND NONINVASIVE MONITORING OF RESPIRATION, ANESTHESIA DELIVERY, LUNG FUNCTION, AND CARDIAC OUTPUT. MASS SPEC, WHILE CURRENTLY THE MOST POPULAR APPROACH TO MEDICAL GAS QUANTITATION, SUFFERS FROM INHERENT USER UNFRIENDL ...

    SBIR Phase II 1987 Department of Health and Human Services
  5. MINIATURIZED RAMAN CLINICAL GAS ANALYZER

    SBC: Biomaterials International Inc            Topic: N/A

    A NEED EXISTS TO QUANTITATE ANESTHETIC AND RESPIRATORY GASES(O2, CO2, N2) IN THE OPERATING ROOM. PREVIOUS WORK HAS SHOWN THAT RAMAN LIGHT SCATTERING CAN BE SUCCESSFULLY UTILIZED FOR MOLECULAR GAS ANALYSIS. THE RAMAN SIGNAL FOR EACH GAS CAN BE SEPARATED FROM THE LASER BEAM RAYLEIGH SCATTER VIA FILTER COMBINATIONS, THUS ELIMINATING THE NEED FOR LARGE, EXPENSIVE MONOCHROMATORS. THIS PROPOSAL ADDRESSE ...

    SBIR Phase I 1987 Department of Health and Human Services
  6. FIBEROPTIC PH SENSOR FOR IN VIVO MEASUREMENTS

    SBC: Biomaterials International Inc            Topic: N/A

    THE DEVELOPMENT OF A FIBEROPTIC PH PROBE IS PROPOSED USING A FLUORESCENT DYE IMMOBILIZED IN A HYDROPHILIC GEL MATRIX. THE MAIN TASKS IN THIS PROJECT ARE: (1) SET-UP OF RESEARCH INSTRUMENTATION FOR MEASURING AND CHARACTERIZING EXPERIMENTAL PROBES, (2) SELECTION AND IMMOBILIZATION OF DYES AT THE TIP OF THE OPTICAL FIBER, AND (3) TEST PH PROBESFOR SIGNAL INTENSITY, PH SENSITIVITY, TIME RESPONSE, PHOT ...

    SBIR Phase I 1987 Department of Health and Human Services
  7. HEPARIN ADSORPTION COMPLEXES FOR BLOOD COMPATIBILITY

    SBC: Biomaterials International Inc            Topic: N/A

    THE ANTICOAGULANT, HEPARIN, WILL BE DERIVATIZED WITH BIOLOGICALLY COMPATIBLE HYDROPHOBIC MACROMOLECULES TO MAKE THEM WATER INSOLUBLE. THIS DERIVATIZATION WILL OCCUR THROUGH HYDROPHILIC SPACER GROUPS, ALLOWING THE HEPARIN TO EXTEND INTO THE AQUEOUS ENVIRONMENT AND RETAIN ITS BIOACTIVE CONFIGURATION. THESE HEPARIN DERIVATIVES WILL BE SOLVENT-COATED ONTO BIOMEDICAL DEVICES TO PROVIDE LOW-COST, IMMOBI ...

    SBIR Phase I 1987 Department of Health and Human Services
  8. POLYMERIC MATERIALS TO MINIMIZE CELL AND TISSUE ADHESION

    SBC: Biomaterials International Inc            Topic: N/A

    USING THE MOUSE PERITONEAL IMPLANT MODEL, MATERIALS WILL BE EVALUATED FOR THEIR BIOCOMPATIBILITY. THE OBJECTIVE OF THISSTUDY WILL BE TO DEVELOP MATERIALS WITH MINIMAL TENDENCY FORCELLULAR AND TISSUE ADHESION. POLYURETHANES AND SILICONES, MATERIALS WIDELY USED IN BIOMEDICAL DEVICE FABRICATION, WILLBE SYNTHESIZED OR MODIFIED TO YIELD A HIGH CONCENTRATION OF POLYETHER FUNCTIONALITY AT THE POLYMER SUR ...

    SBIR Phase I 1987 Department of Health and Human Services
  9. AN ANALYTICAL DATABASE MANAGEMENT SYSTEM FOR GENETICISTS

    SBC: Dms Systems Inc            Topic: N/A

    THE GOAL OF THIS PROPOSAL IS TO PRODUCE AN ANALYTICAL DATABASE SYSTEM FOR GENETICISTS TO FACILITATE THE TASK OF COLLECTING, ORGANIZING, AND MAINTAINING DATA SPECIFIC TO THIS FIELD. MANY DISPARATE PROGRAMS ARE AVAILABLE FOR THE ANALYSIS OF GENETIC DATA, BUT MOST REQUIRE COMPUTING AND GENETIC ANALYSIS EXPERTISE FOR THEIR USE, AND ALL REQUIRE THE GENETICIST TO DIRECT THE ANALYSIS STRATEGY APPROPRIATE ...

    SBIR Phase I 1987 Department of Health and Human Services
  10. CONTROLLED IONTOPHORETIC DELIVERY OF NARCOTICS

    SBC: Jmw Acquisition Company Inc            Topic: N/A

    THE AIM OF THIS PROPOSAL IS TO INVESTIGATE AND DEVELOP LONG-TERM IONTOPHORETIC PROCEDURES FOR DELIVERY OF NARCOTIC AGENTS. IONTOPHORESIS HAS BEEN KNOWN FOR A LONG TIME, BUT ITS APPLICATION IS LIMITED TO SHORT-TERM PROCEDURES (15 TO 30 MINUTES). THE MAJOR IMPEDIMENT TO LONG-TERM USE IS THE FORMATION OF ELECTROLYTIC PRODUCTS AT THE ELECTRODE, LOWERING THE EFFICIENCY OF DRUG TRANSPORT AND CAUSING BUR ...

    SBIR Phase I 1987 Department of Health and Human Services

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