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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Software for improved scientific references using the Web-Citation Protocol

    SBC: ABRATECH CORPORATION            Topic: NLM

    DESCRIPTION (provided by applicant): This project will develop software for Web-based Compendia , which is defined as a concise, yet comprehensive, organization of a body of knowledge, together with its evaluation. Such Compendia will for a basis for Outlined-Knowledge on the Web. The software will use a new standard, the Web-Citation-Protocol. The Protocol offers a new method of creating refer ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  2. Decreasing Calories, Fat and Sodium in Restaurant Meals for Widespread Industry Ado

    SBC: ACCENTS ON HEALTH, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): The prevalence of nutrition-related conditions (overweight/obesity, cancer, diabetes, heart disease, etc.) among Americans is widely documented. During the last twenty years, the frequency of dining out has increased, with Americans currently eating restaurant-prepared foods an average of five to six times per week. Compared to meals prepared at home, restauran ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  3. Chromatin Immunoprecipitation (ChIP) Assay Development for FFPE human brain secti

    SBC: ACTIVE MOTIF, INC.            Topic: NIMH

    DESCRIPTION (provided by applicant): Depression is the leading cause of disability among individuals between the ages of 15-44, affecting approximately 21 million Americans and is the leading cause of suicide. Current diagnostic tools available for medical professionals are limited to questionnaires and other inherently subjective approaches. Improving accuracy of diagnosis has been cited as a pre ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  4. Automated Systems for Detection and Molecular Characterization of Circulating Tum

    SBC: ADVANCED CELL DIAGNOSTICS, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): The detection and enumeration of circulating tumor cells (CTCs) has the potential to become a very powerful tool in cancer diagnosis and treatment. However, current technologies for CTC detection are not yet established in routine clinical practice. One reason is that CTCs are present in blood at an extremely low concentration of one in 10 million white blood c ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  5. Discovery of inhibitors of the lipopolysaccharide synthesis pathway enzymes LpxA

    SBC: Zenobia Therapeutics, Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): Bacterial resistance to antibiotics has been an evolving problem since the dawn of the antibiotics era, requiring consistent scientific advances over the years in antibiotic discovery, epidemiological surveillance and infection control techniques to overcome the then-current clinical problem. One way to address resistance mechanisms is to attack the bacteria on ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  6. Automated High Throughput Cryopreservation Using Microfluidics

    SBC: 21st Century Medicine, Inc.            Topic: NCRR

    DESCRIPTION (provided by applicant): The long-term objective of this research is to develop a device that will improve the efficacy of cryopreserving cells in suspension and small pieces of tissue. Having improved means for cell and tissue cryopreservation can increase the effectiveness of bioresource centers containing banks of high quality cells and tissues for research. It can also provide cryo ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  7. Targeting a Poor Prognosis Marker for Tumor Therapy

    SBC: Advanced Targeting Systems            Topic: NCI

    DESCRIPTION (provided by applicant): Targeting a Poor Prognosis Marker for Tumor Therapy Summary The purpose of this proposal is to develop a medical treatment for the elimination of metastatic cancers. According to the National Cancer Institute, the survival rate for many types of cancer has improved in recent years; however, it is still the second leading cause of death in the United States. ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  8. RNA Resource for Synthetic Lethal Screening of DNA Repair and

    SBC: ALLELE BIOTECHNOLOGY AND PHARMACEUTICALS            Topic: OPPNE

    The objectives of this proposal are to develop gene silencing reagents, and to test/validate their use in synthetic lethal screening of DNA damage signaling and repair pathways. Making such reagents available will provide the efficiency and convenience that cancer researchers currently need to find novel strategies and therapeutics against cancer. DNA repair pathway genes have been shown to en ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  9. Treatment of Acute Coronary Syndromes with Recombinant LCAT Infusion

    SBC: ALPHACORE PHARMA, LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): The hallmark of atherosclerosis is the accumulation of cholesterol in arteries, resulting in plaque which can lead to a heart attack (myocardial infarction (MI)). The excess cholesterol causes inflammation, promotes plaque instability, and in later stages, narrows the vessel lumen to obstruct blood flow. Normally, cholesterol is removed from arteries and deli ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  10. X

    SBC: Altor BioScience, LLC            Topic: N/A

    X

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
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