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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Embedded Access to Signing of Science Terms and Definitions
SBC: VCOM3D INC Topic: NADeaf and hard-of-hearing students may lag behind their hearing peers in English literacy and in science, technology, engineering, and mathematics (STEM). Evaluations in classroom and informal environments have demonstrated the efficacy of the dictionaries in increasing student engagement and mastery of math and science content and vocabulary. This project develops a cloud-based service and corresp ...
SBIR Phase I 2015 Department of Health and Human ServicesAdministration for Community Living -
Novel selective alpha4beta2 nicotinic receptor antagonists for smoking cessation
SBC: ASSUAGE PHARMACEUTICALS, INC. Topic: NIDADESCRIPTION provided by applicant Smoking remains the number one avoidable cause of death in the United States and costs the economy tens of billions of dollars every year Current therapies include nicotine replacement with a patch or gum inhibition of the dopamine system with bupropion and partial activation of the neuronal nicotinic acetylcholine receptor nAChR with varenicline Non ...
SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health -
Combination Immunotherapy of a Novel Superagonist IL-15 Complex and Anti-CD20 Antibody for Indolent Non-Hodgkin Lymphoma
SBC: Altor BioScience, LLC Topic: 102DESCRIPTION provided by applicant Non Hodgkin lymphoma NHL is the most commonly diagnosed hematologic malignancy in the U S with over new cases and about deaths due to NHL expected in Over one third of all cases are slow growing or indolent NHL iNHL which affect older adults and typically present as advanced disease The initial treatment of iNHL consists of an anti CD ...
SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health -
Developing A Novel Therapy for Diabetic Retinopathy
SBC: Charlesson, LLC Topic: WDESCRIPTION provided by applicant Diabetic retinopathy DR is a common complication of diabetes and a leading cause of vision loss in the United States Although the anti vascular endothelial growth factor VEGF drugs have shown impressive efficacies on wet age related macular degeneration AMD they are only effective in approximately of patients with DR likely due to the multi factori ...
SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health -
Improving drug safety for pregnant women by delivering current and authoritative information via mobile devices
SBC: RightAnswer.Com, Inc. Topic: NCBDDDDESCRIPTION provided by applicant In the United States nearly of all pregnant women are prescribed one or more drugs during pregnancy The impact on public health is significant Approximately birth defects are due to drugs taken during pregnancy Additionally many patients fear that exposure to any medication during pregnancy will cause harm to the embryo fetus and this fear has ...
SBIR Phase I 2015 Department of Health and Human ServicesCenters for Disease Control and Prevention -
Multi-Scale Simulation Framework for Heterogeneous Energetic Materials
SBC: STREAMLINE NUMERICS, INC. Topic: AF15AT28ABSTRACT: Designing propulsion devices and munitions for precise operational performance demands control and manipulation of energy released by explosive materials. It is well recognized that the initiation of energetic materials in explosives applications depends sensitively on hot-spots that originate from various heterogeneities at the meso (particle)-scale such as voids, defects, dislocations ...
STTR Phase I 2015 Department of DefenseAir Force -
Advanced Heat Exchanger (HEX) Scaling Methodologies for High-Performance Aircraft
SBC: Spiritech Advanced Products, Inc. Topic: AF073050ABSTRACT: The current state-of-the-art for heat exchanger (HEX) analysis and design relies on analytical approaches which are difficult to scale and highly empirical, thus making the ability to optimize advanced heat transfer devices improbable without comprehensive characterization efforts. The design standard for predicting heat exchanger performance is a set of empirical data developed more th ...
SBIR Phase II 2015 Department of DefenseAir Force -
Receptors, Ligands, and Catalysts on Demand using Expanded Genetic Alphabets
SBC: FIREBIRD BIOMOLECULAR SCIENCES LLC Topic: 100DESCRIPTION provided by applicant Technology to deliver molecules andquot on demandandquot that bind to targets or catalyze reactions of a technologistandapos s choosing would have enormous commercial value in research manufacturing and medicine Thus this has been a andquot holy grailandquot of molecular science for a half century Even today chemical theory is inadequate to support de ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Protection of Pancreatic Beta Cell Mass through Inhibition of BACE-2 for Treatment of Diabetes
SBC: Jortan Pharmaceuticals Inc. Topic: 200DESCRIPTION provided by applicant Diabetes is the th leading cause of death in the U S and some million new cases are diagnosed per year Nearly million in the U S have diabetes with annual healthcare costs estimated at $ billion Diabetes patients suffer from complications associated with diminished or dysfunctional insulin levels The prognosis for diabetes patients is grim If ...
SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Development of DT-109 as an oral therapeutic for type 2 diabetes
SBC: Diapin Therapeutics LLC Topic: 200DESCRIPTION provided by applicant Type diabetes T D is chronic disease characterized by high blood glucose and rapidly emerged as a global health care problem that threatens to reach pandemic levels by Nearly million people worldwide are currently affected by diabetes Diabetes is a major cause of heart disease and stroke and also leads to other complications such as vision loss ...
SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health