Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. Embedded Access to Signing of Science Terms and Definitions

    SBC: Vcom3D, Inc.            Topic: NA

    Deaf and hard-of-hearing students may lag behind their hearing peers in English literacy and in science, technology, engineering, and mathematics (STEM). Evaluations in classroom and informal environments have demonstrated the efficacy of the dictionaries in increasing student engagement and mastery of math and science content and vocabulary. This project develops a cloud-based service and corresp ...

    SBIR Phase I 2015 Department of Health and Human Services
  2. Novel selective alpha4beta2 nicotinic receptor antagonists for smoking cessation

    SBC: ASSUAGE PHARMACEUTICALS, INC.            Topic: NIDA

    DESCRIPTION provided by applicant Smoking remains the number one avoidable cause of death in the United States and costs the economy tens of billions of dollars every year Current therapies include nicotine replacement with a patch or gum inhibition of the dopamine system with bupropion and partial activation of the neuronal nicotinic acetylcholine receptor nAChR with varenicline Non ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Combination Immunotherapy of a Novel Superagonist IL-15 Complex and Anti-CD20 Antibody for Indolent Non-Hodgkin Lymphoma

    SBC: Altor Bioscience LLC            Topic: 102

    DESCRIPTION provided by applicant Non Hodgkin lymphoma NHL is the most commonly diagnosed hematologic malignancy in the U S with over new cases and about deaths due to NHL expected in Over one third of all cases are slow growing or indolent NHL iNHL which affect older adults and typically present as advanced disease The initial treatment of iNHL consists of an anti CD ...

    SBIR Phase II 2015 Department of Health and Human Services
  4. Developing A Novel Therapy for Diabetic Retinopathy

    SBC: Charlesson, LLC            Topic: W

    DESCRIPTION provided by applicant Diabetic retinopathy DR is a common complication of diabetes and a leading cause of vision loss in the United States Although the anti vascular endothelial growth factor VEGF drugs have shown impressive efficacies on wet age related macular degeneration AMD they are only effective in approximately of patients with DR likely due to the multi factori ...

    SBIR Phase II 2015 Department of Health and Human Services
  5. Improving drug safety for pregnant women by delivering current and authoritative information via mobile devices

    SBC: RightAnswer.Com, Inc.            Topic: NCBDDD

    DESCRIPTION provided by applicant In the United States nearly of all pregnant women are prescribed one or more drugs during pregnancy The impact on public health is significant Approximately birth defects are due to drugs taken during pregnancy Additionally many patients fear that exposure to any medication during pregnancy will cause harm to the embryo fetus and this fear has ...

    SBIR Phase I 2015 Department of Health and Human Services
  6. Receptors, Ligands, and Catalysts on Demand using Expanded Genetic Alphabets

    SBC: FIREBIRD BIOMOLECULAR SCIENCES LLC            Topic: 100

    DESCRIPTION provided by applicant Technology to deliver molecules andquot on demandandquot that bind to targets or catalyze reactions of a technologistandapos s choosing would have enormous commercial value in research manufacturing and medicine Thus this has been a andquot holy grailandquot of molecular science for a half century Even today chemical theory is inadequate to support de ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Protection of Pancreatic Beta Cell Mass through Inhibition of BACE-2 for Treatment of Diabetes

    SBC: Jortan Pharmaceuticals Inc.            Topic: 200

    DESCRIPTION provided by applicant Diabetes is the th leading cause of death in the U S and some million new cases are diagnosed per year Nearly million in the U S have diabetes with annual healthcare costs estimated at $ billion Diabetes patients suffer from complications associated with diminished or dysfunctional insulin levels The prognosis for diabetes patients is grim If ...

    SBIR Phase I 2015 Department of Health and Human Services
  8. Development of DT-109 as an oral therapeutic for type 2 diabetes

    SBC: Diapin Therapeutics LLC            Topic: 200

    DESCRIPTION provided by applicant Type diabetes T D is chronic disease characterized by high blood glucose and rapidly emerged as a global health care problem that threatens to reach pandemic levels by Nearly million people worldwide are currently affected by diabetes Diabetes is a major cause of heart disease and stroke and also leads to other complications such as vision loss ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Kits for high-multiplexed detection of RNA viruses in complex biological samples

    SBC: FIREBIRD BIOMOLECULAR SCIENCES LLC            Topic: 300

    DESCRIPTION provided by applicant The public health challenges from RNA viruses are at a tipping point with dengue moving up Florida human transmission of chickungunya now established in Florida and transmitted by different mechanism Ebola While these have long been a challenge their incidence has been predominantly overseas In addition the health hazards of other RNA viruses better k ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Development of DT-110 as an oral therapeutic for type 2 diabetes

    SBC: Diapin Therapeutics LLC            Topic: 200

    DESCRIPTION provided by applicant Type diabetes is a chronic debilitating disease that threatens to reach pandemic level by Nearly million people worldwide are currently affected by diabetes and more than of patients with type diabetes die of cardiovascular causes However no particular diabetes medication to date is considered superior in the minimization of the risk of card ...

    SBIR Phase II 2015 Department of Health and Human Services
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