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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. A DIGITAL TELEMETRY MONITOR WITH MODULAR FEATURES

    SBC: United States Control            Topic: N/A

    N/A

    SBIR Phase I 1987 Department of Health and Human Services
  2. ANTIGENICITY OF GONOCOCCAL PILUS OLIGOMERS

    SBC: Immunomed Corpon            Topic: N/A

    THE DEVELOPMENT OF A SAFE AND EFFICACIOUS VACCINE FOR GONORRHEA BASED ON OLIGOMERS FROM PILI IS A MAJOR GOAL OF IMMUNOMED CORPORATION. EARLY ATTEMPTS TO DEVELOP GONORRHEA VACCINES USING INTACT PILI FAILED BECAUSE OF ANTIGENIC DIVERSITY AMONG THE BACTERIAL STRAINS IN THE POPULATION. A PRELIMINARY STUDY OF OLIGOMERS FROM THE TYPE 2 COLONIAL FORM OF NEISSERIA GONORRHOEAE HAS SHOWN THAT THEY WERE BETT ...

    SBIR Phase I 1987 Department of Health and Human Services
  3. AUTOMATED ELECTROPHYSIOLOGIC HEARING SCREENING DEVICE

    SBC: Artificial Hearing Systems Cp            Topic: N/A

    HEARING TESTING OF NEWBORNS AND INFANTS USING AUDITORY BRAINSTEM RESPONSES (ABR) HAS GAINED WIDESPREAD ACCEPTANCE AND HAS COME TO BE PREFERRED OVER OTHER LESS ACCURATE TECHNIQUES. ABR'S STRENGTH IS ITS DIRECT MEASUREMENT OF AUDITORY FUNCTION, WHICH RESULTS IN HIGH TEST SPECIFICITY AND SENSITIVITY. CLINICAL USE OF ABR, HOWEVER, IS STILL LIMITED BECAUSE OF THE PROFESSIONAL LABOR-INTENSIVE OPERATION ...

    SBIR Phase II 1987 Department of Health and Human Services
  4. CARRAGEENAN-STABILIZED COLLOIDAL GOLD BIOSENSOR ELECTRODES

    SBC: ALDERON BIOSCIENCES, INC.            Topic: N/A

    N/A

    SBIR Phase I 1987 Department of Health and Human Services
  5. DEVELOPMENT OF A RAPID IMMUNOASSAY FOR SYPHILIS

    SBC: Diamedix Corpon            Topic: N/A

    SYPHILIS, STILL A MAJOR SERIOUS INFECTIOUS DISEASE, CAN BE TREATED EFFECTIVELY IF DIAGNOSED EARLY. THE NUMBER OF DEATHS FROM SYPHILIS IN THE UNITED STATES HAS SHOWN A STEADY DECREASE, BUT THE NUMBER OF SYPHILIS CASES HAS NOT SHOWN A SIGNIFICANT DROP. SEROLOGICAL TESTS PLAY A MAJOR ROLE IN THE DIAGNOSIS OF SYPHILIS. THESE TESTS MUST BE PERFORMED BY QUALIFIED TECHNICIANS IN A LABORATORY. THE PROPOSE ...

    SBIR Phase I 1987 Department of Health and Human Services
  6. DISTRIBUTED DATA MANAGEMENT FOR CANCER CLINICAL TRIALS

    SBC: American Power Jet Company            Topic: N/A

    THIS PROPOSAL SEEKS TO DEVELOP AND IMPLEMENT A DISTRIBUTED DATA MANAGEMENT NETWORK FOR CANCER CLINICAL TRIALS. THE NETWORK WILL BE MICROCOMPUTER BASED AND WILL HAVE AS ITS OBJECTIVE A CENTRALIZED DATABASE FOR MONITORING THE PROGRESSOF CLINICAL TRIALS. FEATURES WILL INCLUDE DATA ENTRY USING PREFORMATTED SCREENS, AUTOMATED ERROR CHECKING, EDITING FACILITIES, DATA SECURITY, AND DATA TRANSFER CAPABILI ...

    SBIR Phase I 1987 Department of Health and Human Services
  7. ECCENTRIC CONTRACTIONS EFFECTS ON MUSCULOSKELETAL AGING

    SBC: Design/analysis Services Co            Topic: N/A

    OSTEOPOROSIS, DEGENERATIVE JOINT DISEASE, AND PRIMARY MUSCLE ATROPHY ARE THREE AGE-RELATED DISORDERS OF THE MUSCULOSKELETAL SYSTEM. OSTEOPOROSIS AFFECTS 90 PERCENT OF WOMEN OVER 75 YEARS, OSTEOARTHRITIS AFFLICTS 80 PERCENT, AND MUSCLE ATROPHY IS PROGRESSIVE WITH AGE. PHYSICAL CONDITIONING RETARDS BONE LOSS, STABILIZES DETERIORATED JOINTS, AND PREVENTS MUSCLE ATROPHY. THE MOST EFFICIENT STIMULUS TO ...

    SBIR Phase I 1987 Department of Health and Human Services
  8. ELCA ASSAY OF CLINICALLY IMPORTANT CLOTTING FACTORS

    SBC: Elcatech, Inc.            Topic: N/A

    A NEW TECHNIQUE HAS BEEN DEVELOPED TO ASSAY CLOTTING FACTORS: SOLID-PHASE FIBRINOGEN AND LABELLED FIBRINOGEN TOGETHER ARE USED AS A SUBSTRATE TO DETECT THROMBIN GENERA- TED FROM THE CLOTTING CASCADE. WHEN THROMBIN CLEAVES BOTH FORMS OF FIBRINOGEN TO FIBRIN, THE LABELLED FIBRIN IN SOLU- TION ASSOCIATES WITH THE SOLID PHASE. THIS TECHNIQUE, WHICHHAS BEEN NAMED "ENZYME-LINKED COAGULATION ASSAY" OR EL ...

    SBIR Phase II 1987 Department of Health and Human Services
  9. HORIZONTAL LIGHT PATH7VISION ENHANCING SYSTEM

    SBC: Ocutech, Inc.            Topic: N/A

    A NOVEL HORIZONTAL LIGHT PATHVISION ENHANCING SYSTEM (HLP-VES) CAPABLE OF 2X TO 6X MAGNIFICATION AND MOUNTED ACROSS THE FACIAL PLANE WILL BE STUDIED 1. SURVEY OF CURRENT USAGE OF TELESCOPIC VISION AIDS; 2. OPTIMIZATION OF OPTICAL DESIGN IN DESIRABLE MAGNIFICATION POWERS INCORPORATING THE HLP-VES PRINCIPLE; 3. PRELIMINARY DESIGNS OF OPTICAL CHASSIS AND MOUNTING; 4. IDENTIFICATION OF COMPONENT SOURC ...

    SBIR Phase II 1987 Department of Health and Human Services
  10. IMMUNOASSAYS FOR SAXITOXINS

    SBC: Hawaii Biotech, Inc.            Topic: N/A

    THE SAXITOXINS ARE NEUROTOXINS AND ARE AMONG THE MOST POTENT NONPROTEIN TOXINS KNOWN. SEVERAL THOUSAND CASES OF PARALYTIC SHELLFISH POISONING OCCUR WORLDWIDE EACH YEAR, WITH A CASE-FATALITY RATE APPROACHING 10 PERCENT. SINCE THERE IS NO ANTIDOTE FOR SUCH POISONING, AVOIDANCE OF CONTAMINATED MATERIAL IS THE ONLY MEANS OF CONTROL. THE CURRENTLY ACCEPTED METHOD OF DETECTING SAXITOXIN AND ITS NATURAL ...

    SBIR Phase I 1987 Department of Health and Human Services
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