Award Data

THE TOPIC OF THIS PROPOSAL IS THE DESIGN OF AN ENVIRONMENTALCONTROL SYSTEM FOR THE MORE THAN TWO MILLION INDIVIDUALS IN THE UNITED STATES WHOSE PHYSICAL AND/OR MENTAL IMPAIRMENTS ARE SO SEVERE THAT THEY ARE UNABLE TO FUNCTION IN THEIR ENVIRONMENT IN A NORMAL AND EFFECTIVE MANNER. A TWO-YEAR COLLABORATIVE RESEARCH EFFORT BETWEEN THE BIOENGINEERING PROGRAM AT THE NATIONAL HEADQUARTERS OF THE ASSOCIA ...

DESCRIPTION (provided by applicant): The objective of this project is to reduce the cost, complete government regulatory compliance tests, obtain FDA classification, and establish FDA quality system standards for producing a new and innovative assistive technology (AT) that permits individuals, who otherwise cannot feed themselves, to do so without assistance from another person after they are pr ...

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DESCRIPTION (provided by applicant): Liver failure secondary to hepatitis, hepatotoxin exposure, and cirrhosis threatens the lives of thousands in the United States alone. Estimates of yearly direct healthcare costs for liver disease in the U.S. range from $60 billion to over $100 billion. Vesta Therapeutics has developed proprietary technologies for the isolation and preservation of primary hepat ...

DESCRIPTION (provided by applicant): The ability to create new cardiac tissue using progenitor cells via engraftment would be a significant advance. However, the existing types of progenitor cells presently in Phase I clinical trials face significant limitations, including lack of evidence that the donor cells (1) produce new cardiac myocytes, versus creating benefits via neoangiogenesis or ventr ...

DESCRIPTION (provided by applicant): The ability to create new cardiac tissue using progenitor cells via engraftment would be a significant advance. However, the existing types of progenitor cells presently in Phase I clinical trials face significant limitations, including lack of evidence that the donor cells (1) produce new cardiac myocytes, versus creating benefits via neoangiogenesis or ventr ...

DESCRIPTION (provided by applicant): The development of a comprehensive hearing simulator is proposed. The simulator will be able to receive acoustic stimuli and output the corresponding auditory evoked potentials (AEP) and otoacoustic emissions (OAE). The simulator will have a broad range of applications including training of technical and audiological staff, determining the adequacy of AEP and O ...

DESCRIPTION (provided by applicant): The objective of this project is to develop a comprehensive and advanced Vestibular Evoked Myogenic Potential (VEMP) testing module as part of an integrated hearing and vestibular assessment ystem that can be used for vestibular screening, testing, ototoxicity monitoring and other related applications. VEMPs are currently acquired using standard Auditory Evoked ...

THE CONTRACTOR SHALL DEVELOP A FUZZY SET METHODOLOGY FOR UNCERTAINTY ANALYSIS IN PROBABILISTIC SEISMIC SAFETY ASSESSMENT OF NUCLEAR POWER PLANTS. FUZZY SET LOGIC WILL BEUSED FOR COLLECTING, QUANTIFYING AND PROPAGATING SUBJECTIVE,ENGINEERING JUDGEMENT USED IN THE UNCERTAINTY ANALYSIS. IN PHASE I, FEASIBILITY OF THE PROPOSED APPROACH WILL BE DEMONSTRATED BY APPLYING IT TO SELECTED PARTS OF A PROBABI ...

DESCRIPTION (provided by applicant): This Phase I STTR proposal seeks funding to transfer technology from the Foundation for Applied Molecular Evolution (nonprofit) to GenoMechanix (for-profit) relating to a strategy for doing "sequencing by synthesis". This strategy involves the incorporation, in a template-directed polymerization step, of a nucleoside triphosphate having its 3'-hydroxyl group ...