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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. AAV2-ASPA-Based Metabolic Intervention for Alzheimer's Disease

    SBC: ASKLEPIOS BIOPHARMACEUTICAL, INC.            Topic: NIA

    Abstract We propose to initiate preclinical development of a gene therapeutic targeted to Alzheimer's Disease. The World Health Organization's and Alzheimer's Disease International's report on Dementia (2012) recognizes that the global burden of AlzheimerDisease is forecast to worsen significantly with prevalence predicted to double every 20 years. Interventions that could prov ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. A biomarker of aging as a predictor of kidney transplant function

    SBC: HEALTHSPAN DIAGNOSTICS, LLC            Topic: NIA

    ABSTRACT The number of kidney transplant candidates on the waiting list continues to increase each year, while the number of kidney donations remains stagnant. The enduring donor shortage compels clinicians to use kidneys from marginal donors, referred toas expanded criteria donors (ECD). ECD kidneys, obtained primarily from older donors, have a higher risk of delayed graft function and graft loss ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. A COMMUNICATION AND CONTROL SYSTEM FOR THE MENTALLY RETARDED

    SBC: Scott Instruments Corp            Topic: N/A

    THE TOPIC OF THIS PROPOSAL IS THE DESIGN OF AN ENVIRONMENTALCONTROL SYSTEM FOR THE MORE THAN TWO MILLION INDIVIDUALS IN THE UNITED STATES WHOSE PHYSICAL AND/OR MENTAL IMPAIRMENTS ARE SO SEVERE THAT THEY ARE UNABLE TO FUNCTION IN THEIR ENVIRONMENT IN A NORMAL AND EFFECTIVE MANNER. A TWO-YEAR COLLABORATIVE RESEARCH EFFORT BETWEEN THE BIOENGINEERING PROGRAM AT THE NATIONAL HEADQUARTERS OF THE ASSOCIA ...

    SBIR Phase I 1987 Department of Health and Human Services
  4. ADAPT-MP: Auto-Diagnostic Adaptive Precision Trainer for Myoelectric Prosthetic users

    SBC: Design Interactive, Inc.            Topic: DHP14011

    TBD

    SBIR Phase I 2014 Department of DefenseDefense Health Agency
  5. A DIGITAL TELEMETRY MONITOR WITH MODULAR FEATURES

    SBC: United States Control            Topic: N/A

    N/A

    SBIR Phase I 1987 Department of Health and Human Services
  6. ADSC Isolation by MMPs

    SBC: Akron Biotechnology, LLC            Topic: NIGMS

    DESCRIPTION (provided by applicant): Mesenchymal stem cells (MSCs) are known to have the capacity for self-renewal and differentiation into mesenchyme-lineage cell types, including osteoblasts, adipocytes, chondrocytes, tenocytes, and myoblasts, and contribute to the regeneration of a variety of mesenchymal tissues. Adipose tissue represents a rich source of mesenchymal stem cells, and provides an ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Affinity Capture Peptides for Clinical Mass Spectrometric Assays in Plasma

    SBC: AFFINERGY, LLC            Topic: NIGMS

    DESCRIPTION (provided by applicant): We will develop the first assay for multiplexed combinations of all 14 Bone Morphogenetic Proteins. Immunoassays are the gold standard for measuring proteins in clinical samples. However these antibody- based tests neither quantitate protein analyte variants, nor multiplex across large numbers of superfamily members. In addition, the availability of polyclona ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. A FUZZY SET APPROACH FOR SEISMIC SAFETY MARGINS ASSESSMENT.

    SBC: Eda Consultants            Topic: N/A

    THE CONTRACTOR SHALL DEVELOP A FUZZY SET METHODOLOGY FOR UNCERTAINTY ANALYSIS IN PROBABILISTIC SEISMIC SAFETY ASSESSMENT OF NUCLEAR POWER PLANTS. FUZZY SET LOGIC WILL BEUSED FOR COLLECTING, QUANTIFYING AND PROPAGATING SUBJECTIVE,ENGINEERING JUDGEMENT USED IN THE UNCERTAINTY ANALYSIS. IN PHASE I, FEASIBILITY OF THE PROPOSED APPROACH WILL BE DEMONSTRATED BY APPLYING IT TO SELECTED PARTS OF A PROBABI ...

    SBIR Phase I 1987 Nuclear Regulatory Commission
  9. A mobile framework to measure ejection fraction by automated non-invasive analysi

    SBC: AVENTUSOFT L.L.C.            Topic: 102

    DESCRIPTION provided by applicant This SBIR Phase I project will develop a novel mobile framework to measure left ventricular ejection fraction as a marker for systolic dysfunction using automated non invasive analysis of cardiac signals Heart disease is the leading cause of death for men and women accounting for more than one third of all U S deaths In total costs associated w ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. A New MicroRNA-1291 Replacement Therapy for Pancreatic Cancer Disease

    SBC: MIRNA THERAPEUTICS, INC.            Topic: NIAAA

    DESCRIPTION (provided by applicant): Pancreatic cancer is the fourth leading cause of cancer-related death in the United States. There is a clear need for more effective therapies to treat deadly pancreatic cancer disease. MicroRNAs (miRNA or miR) are a large group of short, noncoding RNAs that control posttranscriptional gene expression in human cells, and there is increasing evidence for the exi ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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