Award Data

Project Summary Abstract Synthetic arteriovenous grafts AVGs can provide life sustaining vascular access for dialysis patients but are subject to multiple modes of failure and complications related to chronic needle cannulation poor graft identification delayed access and bleeding These graft needle cannulation associated complications translate to millions of dollars in health care expense ...

Project Summary Nucleosomes are the fundamental and repeating units of chromatin consisting of DNA wrapped around a histone octamer Alterations in chromatin structure and function dramatically impact downstream gene expression and cellular physiology This epigenetic regulation is controlled by two major modifications histone post translational modifications PTMs such as histone methylation ...

THE TOPIC OF THIS PROPOSAL IS THE DESIGN OF AN ENVIRONMENTALCONTROL SYSTEM FOR THE MORE THAN TWO MILLION INDIVIDUALS IN THE UNITED STATES WHOSE PHYSICAL AND/OR MENTAL IMPAIRMENTS ARE SO SEVERE THAT THEY ARE UNABLE TO FUNCTION IN THEIR ENVIRONMENT IN A NORMAL AND EFFECTIVE MANNER. A TWO-YEAR COLLABORATIVE RESEARCH EFFORT BETWEEN THE BIOENGINEERING PROGRAM AT THE NATIONAL HEADQUARTERS OF THE ASSOCIA ...

DESCRIPTION (Adapted from Applicant's Abstract): This is a Phase I SBIR application to develop an add on system for fluorescence microscopes to provide control over the incident wavelength and to provide accurate spectral analysis and discrimination of spectral bands in image space. This will be accomplished without moving parts at high speed using improved acousto-optic devises. The proposal foc ...

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The broad, long-term objective of this research is to evaluate a specific phosphorothioate antisense oligodeoxynucleotide targeting the adenosine A1 receptor as an effective asthma therapeutic. Asthma accounts for 1% of all health care expenditures in the United States. Ten percent of adult Americans and perhaps 15% of children suffer from asthma, with about 7,000 deaths ocurring annually from as ...

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For this Phase I SBIR proposal, Vcom3D proposes to design an Advanced Female Trauma Training System that features the accurate representation of anatomical and physiological differences of the women in our nations armed forces, and of the types of injuries that they are most likely to sustain in combat. The training system will include a ruggedized medical manikin and a wireless tablet controller ...

THE CONTRACTOR SHALL DEVELOP A FUZZY SET METHODOLOGY FOR UNCERTAINTY ANALYSIS IN PROBABILISTIC SEISMIC SAFETY ASSESSMENT OF NUCLEAR POWER PLANTS. FUZZY SET LOGIC WILL BEUSED FOR COLLECTING, QUANTIFYING AND PROPAGATING SUBJECTIVE,ENGINEERING JUDGEMENT USED IN THE UNCERTAINTY ANALYSIS. IN PHASE I, FEASIBILITY OF THE PROPOSED APPROACH WILL BE DEMONSTRATED BY APPLYING IT TO SELECTED PARTS OF A PROBABI ...

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