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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Bullet Proof vascular graft to prevent dialysis access cannulation injury

    SBC: Innavasc Medical, Inc.            Topic: 400

    Project Summary Abstract Synthetic arteriovenous grafts AVGs can provide life sustaining vascular access for dialysis patients but are subject to multiple modes of failure and complications related to chronic needle cannulation poor graft identification delayed access and bleeding These graft needle cannulation associated complications translate to millions of dollars in health care expense ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Accelerated discovery of methylation targeted therapeutic development

    SBC: Epicypher, Inc.            Topic: 102

    Project Summary Nucleosomes are the fundamental and repeating units of chromatin consisting of DNA wrapped around a histone octamer Alterations in chromatin structure and function dramatically impact downstream gene expression and cellular physiology This epigenetic regulation is controlled by two major modifications histone post translational modifications PTMs such as histone methylation ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Acoustic lysis and extraction system for limited cell number applications

    SBC: COVARIS, INC.            Topic: 200

    DESCRIPTION provided by applicant Analysis of single cells or cells that are not present in large numbers in the body is important to understanding basic biology and diseases A specific example is cancer in which changes in DNA in a single cell can lead to that cell reproducing rapidly Similarly studying the proteins that make up these cells can tell us how the changes in DNA result in ch ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Acute Pancreatitis: Renalase as a novel target and agonists as new therapy

    SBC: BESSOR PHARMA, LLC            Topic: 300

    Project Summary Abstract This proposal brings together a top team with diverse and complementary expertise to develop a novel therapeutic agent based on a newly described serum protein renalase RNLS to treat acute pancreatitis AP This protein appears to have a novel protective effect in models of acute tissue injury including AP AP affects more than people year in the USA and can c ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Advanced Female Trauma Training System

    SBC: VCOM3D INC            Topic: DHP16002

    For this Phase I SBIR proposal, Vcom3D proposes to design an Advanced Female Trauma Training System that features the accurate representation of anatomical and physiological differences of the women in our nations armed forces, and of the types of injuries that they are most likely to sustain in combat. The training system will include a ruggedized medical manikin and a wireless tablet controller ...

    SBIR Phase I 2016 Department of DefenseDefense Health Agency
  6. A FUZZY SET APPROACH FOR SEISMIC SAFETY MARGINS ASSESSMENT.

    SBC: Eda Consultants            Topic: N/A

    THE CONTRACTOR SHALL DEVELOP A FUZZY SET METHODOLOGY FOR UNCERTAINTY ANALYSIS IN PROBABILISTIC SEISMIC SAFETY ASSESSMENT OF NUCLEAR POWER PLANTS. FUZZY SET LOGIC WILL BEUSED FOR COLLECTING, QUANTIFYING AND PROPAGATING SUBJECTIVE,ENGINEERING JUDGEMENT USED IN THE UNCERTAINTY ANALYSIS. IN PHASE I, FEASIBILITY OF THE PROPOSED APPROACH WILL BE DEMONSTRATED BY APPLYING IT TO SELECTED PARTS OF A PROBABI ...

    SBIR Phase I 1987 Nuclear Regulatory Commission
  7. A Library of Immunoaffinity Reagents for RNA modifications

    SBC: VISTERRA, INC.            Topic: NIDA

    Project Abstract While there are commercial monoclonal antibodies against several RNA modifications there is a general paucity of immunological tools for the andgt known RNA modifications This lack of immunological tools is hindering study of the emerging roles for modified ribonucleosides as critical players in the many basic cell and organismal processes in viruses bacteria parasites and ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. An adjunct to prolonged exposure therapy for treating refractory PTSD patients

    SBC: MICROTRANSPONDER, INC.            Topic: 101

    DESCRIPTION provided by applicant The Specific Aim of this proposal is to test the feasibility of using vagus nerve stimulation VNS as an adjunct to prolonged exposure therapy PE for treating PTSD patients who are refractory to PE PE is the treatment of choice for such patients However PE is successful in as few as of cases Refractory PTSD patients have high rates of suicide substa ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. An Automated Device for High Yield Mesenchymal Stem Cell Extraction

    SBC: CG SCIENTIFIC INC            Topic: 100

    DESCRIPTION provided by applicant This project aims to develop an automated device for extracting mesenchymal stem cells MSCs in clinically relevant quantities from adipose tissues for treating many serious diseases including myocardial infarction diabetes liver cirrhosis and graft versus host disease Over clinical trials to date have established the feasibility safet and in some c ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. An eHealth solution for posttraumatic stress and pain screening integrated in pediatric injury care

    SBC: Radiant Creative Group, LLC            Topic: NICHD

    DESCRIPTION provided by applicant Each year million US children are injured affecting the child his her family and society which often bears the cost Among school age children age to injuries lead to million emergency department ED visits and hospital admissions annually resulting in $ billion in medical costs and $ billion more in work loss costs Approxima ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
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